Last updated: Jul 01, 2020 - 02:00 BST

Title Indication Intervention Actions PatientSelection Sponsor Collaborator Country StartDate EndDate Identifiers Phase Recruitment Status Sites Trial Duration Enrollment Count Contacts LastChanged
The Role of Anticoagulant and Thrombolitic in Treatment of COVID Patients Coronavirus disease 19 infection tissue plasminogen activator alone, unfractional heparin alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tabriz University of Medical Sciences Iran 2020-06-17 IR.TBZMED.REC.1399.127, IRCT20200515047456N1 Phase 3 Clinical Recruiting 0 15 Farid Rashidi, Farid Rashidi, MD 2020-06-30
Insolcov-19: Analytical study of the profile of pro-inflammatory and pro-resolution factors in non-obese males with pulmonary symptomatology resulting from SARS COVID-19 verified with PCR blood analysis Coronavirus disease 19 infection, Inflammatory disease, Viral pneumonia blood testing alone Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Insud Pharma Chile 2020-06-29 19 Junio 2020, DRKS00022337, Insolcov-19 Phase 1 Clinical Not yet recruiting 1 20 Pedro-Antonio Regidor, Rafael Silva Orellana 2020-06-30
A Phase III Trial of Leronlimab for the Treatment of Covid-19 in Severe and Critically Ill Patients Coronavirus disease 19 infection leronlimab alone CCR5 chemokine antagonist CytoDyn Inc National Institutes of Health and High Specialty Hospitals Mexico Phase 3 Clinical Planned 1 25 2020-06-30
Trauma Healing Project Based on Chinese Mind-Body Wisdom in the novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection Mindfulness practice alone, One to one consultation alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The institute of psychology, Chinese Academy of Sciences China 2020-03-11 2021-03-31 COVID19_IMPACT, ChiCTR2000034164, EOCX331008 Phase Not Applicable Not yet recruiting 1 12 Months Di Long, Yanan Niu 2020-06-30
AK-TIR-COVID-19: Antibody Assesement for COVID-19 Prevalence 2 months After Outbreak in the Hotspot Region of Tirschenreuth/Bavaria Coronavirus disease 19 infection blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kliniken Nordoberpfalz AG Germany 2020-06-29 2020-1112, AK-TIR-COVID-19, DRKS00021813 Phase 4 Clinical Not yet recruiting 1 2500 Thomas Finkenzeller 2020-06-30
Effect of mandala staining on anxiety in patients with COVID-19 Anxiety disorder, Coronavirus disease 19 infection mandala staining alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Arak University of Medical Sciences and Health Services Iran 2020-07-19 IR.ARAKMU.REC.1399.089, IRCT20180519039711N6 Phase Not Applicable Not yet recruiting 1 60 Dr. alireza kamali, Fatemeh Khademi, Mohamad Golitaleb 2020-06-30
Validation of Rapid Test kit for Antibody (IgG, IgM) detection against COVID19 Coronavirus disease 19 infection Rapid Test Kit alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Maulana Azad Medical College India 2020-07-03 CTRI/2020/06/026120 Phase Not Applicable Not yet recruiting 1 50 Dr Pallavi, Dr Sonal Saxena, Dr Urmila Jhamb, Dr Vikas Manchanda 2020-06-30
A clinical trial of SFA-005 for the potential treatment and prevention of acute respiratory distress syndrome (ARDS) in patients with SARS-CoV-2 virus infection (COVID-19) Coronavirus disease 19 infection, Respiratory distress syndrome SFA-005 alone Free fatty acid receptor 2 agonist, Free fatty acid receptor 3 agonist SFA Therapeutics Phase Not Applicable Planned 0 2020-06-30
A clinical trial of SARS-CoV-2 DNA vaccine (intrademal, COVID-19), Immunomic Therapeutics/EpiVax for the potential intradermal prevention of SARS-CoV-2 infection (COVID-19) Coronavirus disease 19 infection SARS-CoV-2 DNA vaccine (intrademal, COVID-19), Immunomic Therapeutics/EpiVax alone Immunomic Therapeutics Inc, Replicate Bioscience Inc Phase Not Applicable Planned 0 2020-06-30
Vitamin D Supplementation in Patients With COVID-19 Coronavirus disease 19 infection conventional care alone, vitamin D3 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Sao Paulo Brazil 2020-06-01 2020-11-30 30959620.4.0000.0068, NCT04449718 Phase Not Applicable Recruiting 1 6 Months 200 Bruno Gualano, PhD, Rosa Pereira, PhD, MD 2020-06-30
CHICANE: Preoperative Shielding and N/T RT-PCR Swabbing for Elective Cancer Surgery Coronavirus disease 19 infection RT-PCR alone, nose and throat swabbing alone, telephone consult alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Liverpool University Hospitals NHS Foundation Trust UK 2020-06-25 2020-09-25 CHICANE, NCT04449783, SP0355 Phase Not Applicable Not yet recruiting 1 3 Months 150 Peter Gaskell, MBChB, Robert Jones, MBChB 2020-06-30
TARGet Kids! COVID-19 Study of Children and Families Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs) Hospital for Sick Children St Michaels Hospital Canada 2020-04-09 2022-12-31 1000069701, NCT04449978 Phase Not Applicable Recruiting 2 32 Months 1082 Catherine S Birken, MD, Christine Kowal, MSc, Dalah C Mason, MPH, Dalah Mason, MPH, Jonathon Maguire, MD 2020-06-30
A phase II clinical trial of tridecasodium pixatimod for the treatment of COVID-19 Coronavirus disease 19 infection tridecasodium pixatimod alone Coronavirus spike glycoprotein inhibitor, FGF-1 ligand inhibitor, FGF-2 ligand inhibitor, Heparanase inhibitor, VEGF ligand inhibitor Zucero Therapeutics Ltd US Phase 2 Clinical Planned 1 2020-06-30
Safety, Tolerability and Immunogenicinity of a Coronavirus-Like Particle COVID-19 Vaccine in Adults Aged 18 to 55 Years Coronavirus disease 19 infection adjuvant A adjuvanted coronavirus-like particle COVID-19 vaccine alone, adjuvant B adjuvanted coronavirus-like particle COVID-19 vaccine alone, coronavirus-like particle COVID-19 vaccine alone, coronavirus-like particle COVID-19 vaccine unadjuvanted alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Medicago Inc 2020-07-10 2021-04-30 CP-PRO-COVLP-019, NCT04450004 Phase 1 Clinical Not yet recruiting 0 9 Months 180 Brian J Ward, MD 2020-06-30
COVIDiet-Int: Changes in Dietary Behaviors During the COVID-19 Outbreak Confinement in the Adult Population Coronavirus disease 19 infection MEditerranean Diet Adherence Screener (MEDAS) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Granada Bezmialem Vakif University, Centro Hospitalar e Universitário de Coimbra, E.P.E., Institute for Public Health (EU), Institute of Technology Sligo, Jozef Stefan Institute, Lithuanian University of Health Sciences, Ss. Cyril and Methodius University of Skopje, University of Athens, University of Belgrade, University of Kuwait, University of Sarajevo, University of Southern Denmark, University of Zagreb, Uniwersytet Przyrodniczy w Poznaniu Spain 2020-03-20 2021-06-30 1526/CEIH/2020, COVIDiet-Int, NCT04449731 Phase Not Applicable Recruiting 1 15 Months 30000 Belén García-Villanova Ruíz, PhD, Celia Rodríguez Pérez, Celia Rodríguez Pérez, PhD, Celia Rodríguez-Pérez, PhD, Eduardo Jesús Guerra-Hernández, PhD, Esther Molina-Montes, PhD, María Dolores Ruíz López, PhD, María Dolores Ruíz-López, PhD, Reyes Artacho Martín-Lagos, PhD, Vito Verardo, PhD 2020-06-30
Clinical Features of Severe Patients With COVID-19 Coronavirus disease 19 infection, Viral pneumonia CT scan alone, arterial ultrasound alone, echocardiography alone, electrocardiography alone, venous ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Federal Research Center for Specialized Types of Medical Care and Medical Technologies" of FMBA Russian Federation 2020-04-06 2020-08-31 COVID-ICU, NCT04450017 Phase Not Applicable Recruiting 1 4 Months 150 Irina A Mandel, PhD, Tatiana V Klypa, Dr.Med.Sc. 2020-06-30
A randomized, double-blind, placebo-controlled, Phase II trial investigating the safety and efficacy of C-21 in hospitalized subjects with COVID-19 infection not requiring mechanical ventilation Coronavirus disease 19 infection VP-01 alone Angiotensin II AT-2 receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) QED Clinical Services India Pvt Ltd, Vicore Pharma AB Russian Federation, India, UK, Ukraine 2020-05-06 2020-001502-38, CTRI/2020/06/026192, VP-C21-006 Phase 2 Clinical Recruiting 12 100 Dr Kartikeya Parmar, Mimi Flensburg, Mr Gajendrasinh Chanchu, Mr Ranjan Ranjesh 2020-06-30
To study the safety and efficacy of Vitamin D3, Vitamin K2-7 and magnesium , in prevention of COVID 19 infection in health care professional (HCP) Coronavirus disease 19 infection Variable regimens including Magnesium Glycinate , Vitamin K2 , vitamin D3 Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Suraksha Pharma Private Limited India 2020-08-01 CTRI/2020/06/026191, MUR/01/2020 Phase 2 Clinical Not yet recruiting 1 500 AVN Sridhar, Dr Sudarsi B 2020-06-30
Clinical trial of herbal supplement as an immunomodulator in adult Covid 19 positive patients Coronavirus disease 19 infection standard treatment alone, ACT 13 plus ACT12 Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) GPLIFE HEALTHCARE PRIVATE LIMITED India 2020-07-05 CTRI/2020/06/026187, PROTOCOL NO- MHC/CT/20-21/002 Phase not specified Status not specified 1 60 Pawan Kumar Singh, Shridhar Pandya, Tushar V Patil 2020-06-30
Homoeopathy as an add-on in treatment of COVID-19 Coronavirus disease 19 infection homoeopathic medicine therapy alone, standard treatmet alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Council for Research in Homoeopathy India 2020-07-08 CTRI/2020/06/026195 Phase 2/Phase 3 Clinical Not yet recruiting 2 300 Dr Anil Khurana, Dr Anupriya, Dr Debadatta Nayak, Dr Juhi Gupta 2020-06-30
A study of drug Lithium on patients of Covid 19 disease Coronavirus disease 19 infection Variable regimens including azithromycin , hydyoxychloroquine , lithium carbonate Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) LNJP Hospital, Maulana Azad Medical College India 2020-07-30 CTRI/2020/06/026193 Phase 2 Clinical Recruiting 0 100 Dr Sumit Sural 2020-06-30
AMMURAVID: A study with immunotherapy for Moderate COVID-19 Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia Urbason alone, baricitinib alone, canakinumab alone, sarilumab alone, siltuximab alone, tocilizumab (subcutaneous), Roche/Chugai alone Heat shock protein inhibitor, IL-6 receptor antagonist, Immunoglobulin G1 agonist, Interleukin-1 beta ligand inhibitor, Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) SOCIETA' ITALIANA MALATTIE INFETTIVE E TROPICALI The Italian Medicines Agency Italy 2020-04-27 2020-001854-23, AMMURAVID, AMMURAVID Phase 2/Phase 3 Clinical Recruiting 1 1400 Malattie Infettive 2020-06-30
The effect of bromelain and montelukast in COVID-19 patients Coronavirus disease 19 infection, Cough, Dyspnea, Fever Anaheal capsule (Parmon Amin Health Company) alone, Anaheal capsule (Parmon Amin Health Company) plus montelukast sodium Leukotriene D4 antagonist Shaheed Beheshti Medical University Iran 2020-04-20 IR.SBMU.NRITLD.REC.1399.060, IRCT20150725023332N3 Phase 3 Clinical Recruiting 1 60 Afshin Zarghi, Alireza Jahangirifard, Behrooz Farzanegan, Seyed Bashir Mirtajani 2020-06-29
Drug Trial to Evaluate Efficacy and Safety of an Ayurvedic Formulation as Adjunct Treatment to Standard of Care for the management of Mild to Moderate COVID-19 Patients Coronavirus disease 19 infection, Viral pneumonia AYUSH 64 alone, Samshamani Vati Plus alone, Standard of Care alone, Yashtimadhu alone, Guduch plus Pippali Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Council of Scientific and Industrial Research (India), Ministry of Ayush India 2020-07-20 COVID 19/AYUSH-ICMR 2020/Adjunct Protocol-AF-II, CTRI/2020/06/026161 Phase Not Applicable Not yet recruiting 0 140 Dr Dilip Mondhe, Dr Sushila Kataria, Mr Chandu Devanpally, Pranjal Ausekar 2020-06-30
COVID-19 in dialysis patients Coronavirus disease 19 infection, End stage renal disease Hemodialysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Seth GS Medical College India 2020-06-26 CTRI/2020/06/026152 Phase Not Applicable Not yet recruiting 0 120 Dr Sayali Thakare, Dr Tukaram Jamale 2020-06-30
Psychological Assessment of adult COVID-19 patients Coronavirus disease 19 infection Psychological Assessment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) KIMS Hospital India 2020-07-06 CTRI/2020/06/026188 Phase Not Applicable Not yet recruiting 1 240 Jayaprakash Russell Ravan 2020-06-29
Steroids and unfractionated heparin in critically-ill patients with pneumonia from COVID-19 infection. A multicenter, interventional, randomized, three-arms study design Coronavirus disease 19 infection, Viral pneumonia Veracer plus methylprednisolone (Pfizer) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Modena Italy 2020-05-14 2020-001921-30, STAUNCH-19 Phase 3 Clinical Recruiting 1 200 Clinical Trials Quality Team 2020-06-29
MICO: Role of Microparticles in Covid-19 Infection Coronary artery disease, Coronavirus disease 19 infection prothrombinase assay alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg 2020-06-30 2021-11-30 7829, MICO, NCT04448743 Phase Not Applicable Not yet recruiting 0 17 Months 175 2020-06-29
Covid: To Compare the safety and efficacy of Vitamin D, with Magnesium in mild to moderate Covid 19 patients Coronavirus disease 19 infection Magnesium plus Vitamin D3 Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Suraksha Pharma Private Limited India 2020-08-01 CTRI/2020/06/026189, Covid Phase 2 Clinical Not yet recruiting 1 210 AVN Sridhar, Neethi Chandra 2020-06-30
Emergence of the COVID-19 Epidemic in the City of Nice Coronavirus disease 19 infection Healthy volunteers accepted Centre Hospitalier Universitaire De Nice France 2020-02-28 2020-04-04 20DSPCOVID01, NCT04449094 Phase Not Applicable Completed 1 1 Month 200 2020-06-30
Characterization of Reverse Triggering and Other Asynchronies in COVID-19 Patients Under Invasive Mechanical Ventilation Coronavirus disease 19 infection, Respiratory distress syndrome asynchronies detection alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Corporacion Parc Tauli Spain 2020-03-09 2020-06-30 NCT04448782, RT COVID-19 Phase Not Applicable Recruiting 1 3 Months 30 Candelaria De Haro, MD, Candelaria de Haro 2020-06-30
Knowledge, Attitude and Practice of Dental Students About COVID-19 Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs) Melaka Manipal Medical College Malaysia 2020-04-25 2020-06-20 MELAKAMMC, NCT04449081 Phase Not Applicable Completed 1 1 Month 215 Rajesh Hosadurga, Ph.D 2020-06-30
Hydro-STOP-COVID19: Hydroxychloroquine sulfate early administration in symptomatic out of hospital COVID-19 positive patients Coronavirus disease 19 infection Plaquenil alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ASUR (Azienda Sanitaria Unica Regionale) Marche Italy 2020-04-09 2020-001558-23, COFID19-AIFA17/2020, Hydro-STOP-COVID19 Phase 3 Clinical Recruiting 1 216 UOC Cardiologia ASUR AV5 2020-06-30
A clinical trial of SK1-I for the potential treatment of COVID-19 Coronavirus disease 19 infection SK1-I alone Sphingosine kinase 1 inhibitor Enzo Biochem Inc Phase Not Applicable Planned 0 2020-06-29
PAWS-COVID-19: Pediatric Airway Complications COVID-19 Registry Coronavirus disease 19 infection, Hypoxia, Respiratory disease airway management alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Boston Children’s Hospital Ann & Robert H Lurie Children's Hospital of Chicago, Children's Hospital Colorado, Childrens Hospital of Philadelphia, Perth Children's Hospital, Royal Hospital for Sick Children, The Gaslini Institute US 2020-04-01 2025-12-31 IRB-P00035427, NCT04449042, PAWS-COVID-19 Phase Not Applicable Recruiting 1 69 Months 15000 John E Fiadjoe, MD, Mary Lyn Stein, Mary Lyn Stein, MD, Pete Kovatsis, MD 2020-06-30
Mental Health of Health Care Workers during COVID-19 pandemics Coronavirus disease 19 infection, Psychotic disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kalinga Institute of Medical Sciences India 2020-07-06 CTRI/2020/06/026184, r2cd58 Phase Not Applicable Not yet recruiting 1 100 RAMA CHANDRA DAS 2020-06-30
COVAL-NANCY: Epidemiological Study of Seroprevalence Against the SARS-CoV-2 Virus (COVID-19) Coronavirus disease 19 infection ELISA alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Nancy, France Métropole du Grand Nancy, Université De Lorraine France 2020-06-30 2020-08-31 2020PI128, COVAL-NANCY, NCT04448769 Phase Not Applicable Not yet recruiting 1 2 Months 2000 Evelyne Schvoerer, Karine LEGRAND, Marjorie STARCK 2020-06-30
CiaoCorona: Longitudinal Study of Seroprevalence of SARS-CoV-2 Antibodies and Development of Immunity in School Children Coronavirus disease 19 infection COVID-19 antibody testing alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) University of Zurich Foundation Swiss School of Public Health Switzerland 2020-06-16 2021-03-31 2020-01336, CiaoCorona, NCT04448717 Phase Not Applicable Recruiting 1 9 Months 2500 Susi Kriemler, Dr.med., Susi Kriemler, Prof. 2020-06-30
Herbal Steaminhaler clinical trial on COVID patients Coronavirus disease 19 infection AZADVIR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HAOMA WELLNESS CENTER India 2020-07-04 CT/AZADVIR /2020, CTRI/2020/06/026181 Phase 3 Clinical Not yet recruiting 1 40 Kavya Kannoth Shaji, SHAJI KANNOTH 2020-06-30
INTERCOP: Clinical Study for the Treatment With Interferon-beta-1a (IFNbeta-1a) of COVID-19 Patients Coronavirus disease 19 infection, Viral pneumonia interferon beta-1a alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) IRCCS San Raffaele Italy 2020-07-31 2021-04-30 INTERCOP, INTERCOP, NCT04449380 Phase 2 Clinical Not yet recruiting 1 9 Months 126 Emanuele Bosi, Professor, Patrizia Rovere Querini, Professor 2020-06-30
ANEMONE: M-5049 Study in Participants With Coronavirus Disease 2019 (COVID-19) Pneumonia Coronavirus disease 19 infection, Viral pneumonia M-5049 alone, standard of care (antiviral treatment) alone TLR-7 antagonist, TLR-8 antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Serono Research Institute Inc Merck KGaA US, Brazil 2020-06-27 2020-11-13 2020-002248-22, ANEMONE, MS200569_0026, NCT04448756 Phase 2 Clinical Not yet recruiting 4 4 Months 150 Communication Center, Medical Responsible, US Medical Information 2020-06-30
Understanding the Mental Health of Migrant Workers During the COVID-19 Outbreak Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yale-NUS College Singapore 2020-06-22 2020-12-31 CCF@EXPO/R001/2020, NCT04448704 Phase Not Applicable Recruiting 1 6 Months 1000 Edina Tan, Jean Liu, PhD 2020-06-29
The association between the neutralizing activity and the amount of antibody in early stages of SARS-CoV-2 infection: A multicenter, observational study Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yokohama City University Japan Agency for Medical Research and Development Japan 2020-07-10 UMIN000040931 Phase Not Applicable Not yet recruiting 1 150 Takahiro Mihara, Takeharu Yamanaka 2020-06-30
The prophylactic effect of oral hydroxychloroquine in close contacts of COVID-19 patients Coronavirus disease 19 infection hydroxychloroquine alone Boushehr University of Medical Sciences Iran 2020-06-21 IR.BPUMS.REC.1399.017, IRCT20200513047426N1 Phase 3 Clinical Recruiting 1 500 Dr.Ramin Rezaee, Ramin Rezaee, Vice chancellery for research and technology 2020-06-29
Effect of medical beer on COVID-19 Coronavirus disease 19 infection, Fever Ministry of Health based COVID-19 treatment alone, medical bear intake alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Isfahan University of medical Sciences Iran 2020-03-29 IR.MUI.MED.REC.1399.078, IRCT20200428047229N1 Phase 3 Clinical Recruiting 1 60 Akram Izadikhah, Hanieh Tahermohammadi, Mojgan Tansaz 2020-06-29
Evaluation of the effect of ivermectin in the treatment of coronavirus infection Coronavirus disease 19 infection ivermectin (Tadbir Kalaye Jam Company) alone, national protocol based standard drug treatment alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mazandaran University of Medical Sciences Iran 2020-05-21 IR.MAZUMS.REC.1399.057, IRCT20111224008507N3 Phase 3 Clinical Recruiting 1 60 Dr Majid Saeidi, Dr. Mohammad Sadegh Rezai, Fatemeh Hosseinzadeh, Modammad Sadegh Rezai, MD, Mohammadsadegh Rezai 2020-06-29
Serological screening and metabolic analysis for evaluation of the immune response to SARS-CoV2 (COVID-19) Coronavirus disease 19 infection Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum der Albert-Ludwigs Universitaet Freiburg Germany 2020-06-01 305/20, DRKS00022292 Phase 0 Clinical Recruiting 0 250 Cornelius Waller 2020-06-30
A phase I/II clinical trial to evaluate the safety, tolerability, immunogenicity and efficacy of Covigenix for treatment of COVID-19 Coronavirus disease 19 infection SARS-CoV-2 DNA vaccine (COVID-19), Entos/ Epivax alone COVID19 Spike glycoprotein modulator Canadian Center for Vaccinology, Entos Pharmaceuticals Inc Canada Phase 1/Phase 2 Clinical Planned 1 2020-06-29
Zinc With Chloroquine/Hydroxychloroquine in Treatment of COVID-19 Coronavirus disease 19 infection Alexoquine (chloroquine) alone, Variable regimens including Alexoquine (chloroquine) , hydroxychloroquine , zinc Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tanta University Egypt 2020-06-23 2020-08-01 NCT04447534, TANTA ZINC CHLOROQUINE Phase 3 Clinical Recruiting 1 1 Month 200 Sherief Abd-Elsalam, Sherief Abd-Elsalam, Ass. Prof., Sherief Abd-Elsalam, ass. prof., Sherief abd-elsalan, ass. prof. 2020-06-29
Expanded clinical use of CIGB-258 in the treatment of serious or critically ill patients by COVID-19 (COVID-19) Coronavirus disease 19 infection CIGB-258 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Center for Genetic Engineering and Biotechnology Ministerio de Salud Publica Cuba 2020-04-27 2020-08-30 IG/CIGB-258/UCE, RPCEC00000321 Phase 2 Clinical Recruiting 2 4 Months 35 Maria Dominguez Orta, Rafael Venegas Rodriguez, Verena Muzio Gonzalez 2020-06-29
A Phase I clinical trial to evaluate the safety, tolerance and preliminary immunogenicity of different doses of a SARS-CoV-2 mRNA vaccine in population aged 18 to 59 years and 60 years and above Coronavirus disease 19 infection, Viral pneumonia mRNA vaccine (Lipid Nano Particle, COVID-19), Walvax Biotechnology/Suzhou Abogen Biosciences alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Guangxi Center For Disease Control & Prevention, Suzhou Abogen Biosciences, Walvax Biotechnology Co Ltd China 2020-06-25 2021-12-31 ChiCTR2000034112 Phase 1 Clinical Not yet recruiting 2 18 Months 168 Lin Yuan, Shuyuan Yang 2020-06-30
Novel coronavirus pneumonia (COVID-19) loaded autologous dendritic cell trial Coronavirus disease 19 infection, Viral pneumonia autologous dendritic cell vaccine (injection, COVID-19), Beijing TIL Therapeutics alone COVID19 Spike glycoprotein modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Beijing TIL Therapeutics Co Ltd, Liaocheng People's Hospital China 2020-04-16 2022-04-15 ChiCTR2000034076 Phase 0 Clinical Recruiting 1 24 Months 25 Shengjun Ma, Xiang Xiaoyu 2020-06-29
Evaluating the effect of Phyllanthus Emblica, Rosa Damascene, Marshmallow and Honey on COVID 19 Coronavirus disease 19 infection Variable regimens including Althaea officinalis , Honey , Phyllanthus emblica , Rosa damascene Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ahvaz University of Medical Sciences Iran 2020-06-27 IR.AJUMS.REC.1399.208, IRCT20200404046937N3 Phase 3 Clinical Recruiting 4 60 Mehran Varnaseri Ghandali, Mohammad Badavi 2020-06-29
CONTROL-COVID: Control of COVID-19 Outbreaks in Long Term Care Coronavirus disease 19 infection, Viral respiratory tract infection favipiravir alone RNA polymerase inhibitor Aged Adults (65-79 yrs), Elderly Adults (80 and over) Appili Therapeutics Inc Applied Health Research Centre (AHRC), Toronto, Mount Sinai Hospital, Sunnybrook Health Sciences Centre, The University Health Network, Unity Health Toronto Canada 2020-06-30 2021-03-31 CONTROL-COVID, CONTROL-COVID-FAVIPIRAVIR-1, NCT04448119 Phase 2 Clinical Not yet recruiting 1 9 Months 760 Allison J McGeer, MD, Yoav Golan, MD 2020-06-26
Covid-19 Lockdown and Deviant Sexual Fantasies Anxiety disorder, Coronavirus disease 19 infection, Sexual deviation Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2020-06-18 2020-10-30 NCT04448405, RECHMPL20_0341 Phase Not Applicable Recruiting 1 4 Months 100 Celine BAIS, Celine BAIS, PhD 2020-06-29
LACCPT: Lagos Covid-19 Convalescent Plasma Trial Coronavirus disease 19 infection Convalescent Plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lagos State Ministry of Health Nigeria 2020-08-01 2020-09-30 LACCPT, PACTR202006760881890 Phase 2 Clinical Not yet recruiting 3 2 Months 100 Akin Abayomi, Bodunrin Osikomaiya, Hussein AbdurRazzaq 2020-06-29
Resveratrol in COVID19 Coronavirus disease 19 infection resveratrol alone, routine drug therapy alone Ahvaz University of Medical Sciences Iran 2020-06-14 IR.AJUMS.REC.1399.175, IRCT20200112046089N1 Phase 3 Clinical Recruiting 1 50 Arash Alghasi, Mohamad Badavi, Mohammad Reza Mahmoudian-Sani 2020-06-29
Safety, Tolerability and Immunogenicity of INO-4800 Followed by Electroporation in Healthy Volunteers for COVID19 Coronavirus disease 19 infection CELLECTRA 2000 alone, INO-4800 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Inovio Pharmaceuticals Inc, International Vaccine Institute, Seoul National University Coalition for Epidemic Preparedness Innovations, The Korea National Institute of Health South Korea 2020-06-22 2022-02-22 IVI COVID19-001, NCT04447781 Phase 1/Phase 2 Clinical Not yet recruiting 1 20 Months 160 Anh Wartel, MD, Chulwoo Rhee, MD,MSc, Eu Suk Kim, MD, Myoung-don Oh, MD 2020-06-29
ANTICOV: An open-label, multicentre, randomised, adaptive platform trial of the safety and efficacy of several therapies, including antiviral therapies, versus control in mild/moderate cases of COVID-19 Coronavirus disease 19 infection, Viral pneumonia Hydroxychloroquine alone, lopinavir + ritonavir alone HIV protease inhibitor Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Barcelona Institute for Global Health, Bernhard-Nocht-Institute for Tropical Medicine, Centre Pasteur du Cameroun, Drugs for Neglected Diseases Initiative, Epicentre (MSF), INSERM, Ifakara Health Institute, Institute of Tropical Medicine, Belgium, Swiss Centre for Scientific Research Sudan, Tanzania, Congo, The Democratic Republic of the, Ghana, Burkina Faso, Guinea, Ethiopia, Uganda, Kenya, Mozambique, Equatorial Guinea, Cameroon, Ivory Coast 2020-07-20 2021-12-31 ANTICOV, PACTR202006537901307 Phase 2 Clinical Not yet recruiting 18 17 Months 3000 James Arkinstall, Nathalie Strub Wourgaft 2020-06-30
Nutritional Habits, and COVID-19 Outcome Coronavirus disease 19 infection Variable regimens including acetylcysteine , hydroxychloroquine , lacorferrin , vitamin C , zinc Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cairo University Egypt 2020-06-01 2020-09-01 1003, NCT04447144 Phase Not Applicable Recruiting 1 3 Months 200 Ahmed M Abdul Ghani, MD, Mona A Hegazy, MD, Mona Hegazy, Mona M Abd-Elmonem Hegazy, MD 2020-06-29
COVID-19 in inpatient care facilities (nursing homes) in Thuringia - it hit us hard! A structured retrospective review of primary care, the work of nurses and the course of infections Coronavirus disease 19 infection Young Adults (18-44 yrs) Thüringer Hausärzteverband e.V. (THV) Germany 2020-05-18 91963/2020/50, DRKS00022035 Phase Not Applicable Recruiting 1 100 Mr. Dr. Ulf Zitterbart 2020-06-29
A phase II/III trial of BC-007 in patients with COVID-19 Coronavirus disease 19 infection BC-007 alone Beta 1 adrenoceptor modulator, COVID19 Spike glycoprotein modulator Berlin Cures GmbH 2020-12-31 Phase 2/Phase 3 Clinical Planned 0 2020-06-26
Self-sampling for the Study of COVID-19 Coronavirus disease 19 infection Atila BioSystems iAMP COVID-19 Detection Kit assay alone, anterior nare self-sampling alone, mid-turbinate self-sampling alone, saliva self-sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medical College of Wisconsin US 2020-07-01 2020-12-31 20-001, NCT04447495 Phase Not Applicable Not yet recruiting 1 6 Months 500 Juan Felix, M.D. 2020-06-29
ICI LOLA: Imaging SARS-CoV-2 Involvement of Leptomeninges, Olfactory and Limbic Areas Coronavirus disease 19 infection, Neoplastic meningitis, Neurological disease, Olfaction disorder MRI alone, gadolinium alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fondation Ophtalmologique Adolf De Rothschild France 2020-05-20 2021-11-20 2020-A01216-33, ICI LOLA, NCT04448054 Phase Not Applicable Recruiting 1 18 Months 100 Amélie YAVCHITZ, Guillaume POILLON 2020-06-30
Ayurveda and Yoga trial for preventing COVID 19 among quarantined individuals exposed to COVID 19 patients Coronavirus disease 19 infection, Psychotic disorder standard prophylactic measure alone, yoga alone, Nishamalaki Churna plus Samshamani Vati Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-06-10 CTRI/2020/06/026147 Phase 2/Phase 3 Clinical Not yet recruiting 1 604 Dr Gautam Sharma 2020-06-29
Ayurveda and Yoga trial for preventing COVID-19 among healthcare workers Coronavirus disease 19 infection, Psychiatric disorder Mindfulness based Yoga module alone, Standard prophylactic mneasures alone, Kalamegha tablet plus Samshamani Vati Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) All India Institute of Medical Sciences India 2020-06-10 CTRI/2020/06/026151 Phase 2 Clinical Not yet recruiting 1 452 Dr Gautam Sharma 2020-06-29
A study to assess the efficacy and safety of MemVax Vaccine in the treatment of covid-19 Coronavirus disease 19 infection MemVax alone CD40 ligand receptor agonist Healthy volunteers accepted Memgen LLC Phase Not Applicable Planned 0 2020-06-26
Mesenchymal Stromal Cell Therapy For The Treatment Of Acute Respiratory Distress Syndrome Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory insufficiency KI-MSC-PL-205 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Uppsala University Sweden 2020-06-17 2025-06-30 2020-02238, ARDS-MSC-205, NCT04447833 Phase 1 Clinical Recruiting 1 60 Months 9 Karl-Henrik Grinnemo, MD, PhD, Oscar Simonsson, MD, PhD 2020-06-29
Covid-19 pneumonia Coronavirus disease 19 infection, Viral pneumonia HOSPITAL RAJA PEREMPUAN ZAINAB II Malaysia 2020-06-25 2020-07-30 55488, NMRR-20-1236-55488 Phase Not Applicable Status not specified 1 1 Month Dr Abdul Karim Bin Othman, Dr Mohd Nazri Ali 2020-06-29
Determinants of SARS-COV2 (COVID-19) Persistence After Convalescence Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Columbia University US 2020-03-26 2021-03-01 AAAS9722, NCT04448145 Phase Not Applicable Recruiting 1 11 Months 250 Lawrence Purpura, MD, MPH, Michael Yin, MD, MS 2020-06-29
Percutaneous Tracheostomy With COVID-19 Coronavirus disease 19 infection aerosol box alone, percutaneous tracheostomy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Canakkale Onsekiz Mart University Turkey 2020-03-20 2020-06-01 NCT04447638, TT17 Phase Not Applicable Completed 1 2 Months 12 Mesut ERBAS 2020-06-29
A clinical trial of anti-SARS-CoV-2 program (COVID-19), NanoViricides for the potential treatment of COVID-19 infection Coronavirus disease 19 infection anti-SARS-CoV-2 program (COVID-19), NanoViricides alone NanoViricides Inc Phase Not Applicable Planned 0 2020-06-26
Study of Mavrilimumab (KPL-301) in Participants Hospitalized With Severe Corona Virus Disease 2019 (COVID-19) Pneumonia and Hyper-inflammation Coronavirus disease 19 infection, Lung inflammation, Viral pneumonia mavrilimumab alone, standard of care therapy alone C-reactive protein inhibitor, Chemokine CC22 ligand inhibitor, GM-CSF receptor antagonist, Hemoglobin scavenger receptor antagonist, Metalloprotease-1 inhibitor, Metalloprotease-3 inhibitor, Small inducible cytokine A17 ligand inhibitor, VEGF gene inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kiniksa Pharmaceuticals Ltd US 2020-06-30 2021-04-30 KPL-301-C203, NCT04447469 Phase 2/Phase 3 Clinical Not yet recruiting 1 10 Months 573 Joshua Denson, MD, Kiniksa Clinical Research Team 2020-06-29
CoDDYC: Dietary Diversity of Young Children During COVID-19 Outbreak: A Longitudinal Study Coronavirus disease 19 infection, Nutritional deficiency IYC feeding practice-dietary counseling alone Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs) University of Malaya Malaysia 2020-06-06 2021-05-31 2020410-8500, CoDDYC, NCT04447209 Phase Not Applicable Recruiting 1 11 Months 300 Hazreen A Majid, BSc MND PhD, Lucy CS Lum, MBBS, MRCP, Lucy Lum Chai See, Lucy Lum, MBBS, MRCP, Mohamad Y Jalaludin, MBBS, MPaeds, Mohammad Y Jalaludin, MBBS MPaeds, Yin M Choo, MBBS 2020-06-29
A phase I trial of SARS-CoV-2 mRNA vaccine for potential treatment of COVID-19 Coronavirus disease 19 infection SARS-CoV-2 mRNA vaccine (COVID-19), Sanofi Pasteur/ Translate Bio alone Sanofi SA Translate Bio MA Inc 2020-12-31 Phase 1 Clinical Planned 0 2020-06-29
A phase I/II clinical trial of recombinant protein-based​ vaccine for potential treatment of COVID-19 Coronavirus disease 19 infection recombinant protein vaccine (COVID-19), UMN Pharma Inc alone Sanofi SA GlaxoSmithKline plc Phase 1/Phase 2 Clinical Planned 0 2020-06-26
Impact of the COVID-19 Pandemic and HRQOL in Cancer Patients and Survivors Anxiety disorder, Cancer, Coronavirus disease 19 infection, Depression online survey alone Healthy volunteers accepted MD Anderson Cancer Center National Cancer Institute US 2020-05-12 2021-07-21 2020-0425, NCI-2020-03900, NCT04447222, P30CA016672 Phase Not Applicable Recruiting 1 14 Months 1242 Lorenzo Cohen 2020-06-29
The Impact of COVID-19 Outbreak on Trans-population's Health in Italy Coronavirus disease 19 infection, Transsexualism web based survey alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Unita Complessa di Ostetricia e Ginecologia Italy 2020-05-20 2020-11-20 NCT04448418, TRANSCOVID-19 Phase Not Applicable Recruiting 1 6 Months 300 Giulia Gava, M.D., maria cristina meriggiola 2020-06-29
Effect of COVID-19 on Platelet Aggregation Coronavirus disease 19 infection, Influenza virus infection, Respiratory disease peripheral vein venipuncture alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Sao Paulo Fundacao de Amparo a Pesquisa do Estado Sao Paulo Brazil 2020-04-29 2020-12-30 NCT04447131, SDC 5089/20/118 Phase Not Applicable Recruiting 1 8 Months 200 Jose Carlos Nicolau, José Carlos Nicolau 2020-06-29
DUR-928 in Subjects With SARS-CoV-2 With Acute Liver or Kidney Injury Coronavirus disease 19 infection, Liver injury, Renal injury DUR-928 (injectable, renal injury/psoriasis/alcoholic hepatitis), DURECT Corp alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) DURECT Corp US 2020-06-30 2021-01-31 C928-020, NCT04447404 Phase 2 Clinical Recruiting 3 7 Months 80 Deborah Scott, Julie Fergus, Robert Gordon, MD 2020-06-29
TITAN: Early Treatment With Ivermectin and Losartan for Cancer Patients With COVID-19 Infection Advanced solid tumor, Coronavirus disease 19 infection, Hematological neoplasm ivermectin plus losartan Angiotensin II AT-1 receptor antagonist, Angiotensin II receptor antagonist, Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto do Cancer do Estado de São Paulo Brazil 2020-07-31 2021-02-28 NCT04447235, NP 1677/20, TITAN Phase 2 Clinical Not yet recruiting 1 7 Months 176 Maria del Pilar Diz, MD, PhD, Pedro Exman, MD 2020-06-29
PRECOV: A randomized, controlled clinical trial on the effects of hydroxychloroquine in the prevention of COVID-19 in healthcare workers at risk Coronavirus disease 19 infection hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Istituto Scientifico H San Raffaele Italy 2020-05-06 2020-001987-28, PRECOV, PRECOV Phase 3 Clinical Recruiting 1 1000 IRCCS Ospedale San Raffaele 2020-06-29
ARCO-Homestudy: Adaptive, Randomized trial for therapy of Coronavirus disease 2019 at home with oral antivirals Coronavirus disease 19 infection Plaquenil alone, darunavir + cobicistat (fixed dose, HIV infection), Janssen R&D/ Gilead alone, favipiravir alone, lopinavir + ritonavir alone Cytochrome P450 3 inhibitor, HIV protease inhibitor, HIV-1 protease inhibitor, RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istituto Nazionale Per Le Malattie Infettive "Lazzaro Spallanzani" Italy 2020-05-14 2020-001528-32, ARCO-Homestudy, ARCO-Homestudy Phase 3 Clinical Recruiting 1 435 Dipartimento di Epidemiologia Digno 2020-06-29
ESCAPE: A phase III, randomized, open-labeled, multicenter study comparing clinical efficacy and safety of intravenous sarilumab plus standard of care compared to standard of care, in the treatment of patients with severe COVID-19 pneumonia Coronavirus disease 19 infection, Inflammatory disease, Viral pneumonia sarilumab alone, standard of care alone IL-6 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istituto Nazionale Per Le Malattie Infettive "Lazzaro Spallanzani" Italy 2020-04-27 2020-001390-76, ESCAPE, ESCAPE Phase 3 Clinical Recruiting 1 171 Immunodeficienze virali 2020-06-29
An adaptive, phase II, randomized, placebo-controlled study to evaluate the safety and efficacy of PL8177 in the treatment of hospitalized adult COVID-19 patients with hypoxemic respiratory failure, with or without mild acute respiratory distress syndrome (ARDS) Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure PL-8177 alone, standard of care alone Melanocortin MC1 receptor agonist Palatin Technologies Inc 2020-12-31 Phase 2 Clinical Planned 0 176 2020-06-26
Maintaining the health of people with and without COVID-19 during isolation Anxiety disorder, Coronavirus disease 19 infection, Lung disease, Upper respiratory tract infection PhysiApp alone, PhysiTrack software alone, Sydney local health district service alone, UberEats alone, anxiety management technique alone, exercise program alone, nutritional advice alone, paper-based exercise program alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Royal Prince Alfred Hospital Australia 2020-06-10 2020-12-16 ACTRN12620000698976 Phase Not Applicable Recruiting 1 6 Months 40 Prof Jennifer Alison 2020-06-29
An exploratory, non-randomized, open-label, single-arm study to evaluate the safety of ADR-001 in patients with severe pulmonary inflammation caused by SARS-CoV-2 infection Coronavirus disease 19 infection, Lung inflammation, Viral pneumonia ADR-001 alone Rohto Pharmaceutical Co Ltd Japan 2020-08-31 2021-12-31 Phase Not Applicable Planned 1 16 Months 6 2020-06-25
A study to assess the effect of gelsolin, BioAegis Therapeutics in patients with COVID-19 pneumonia Coronavirus disease 19 infection, Viral pneumonia gelsolin, BioAegis Therapeutics alone Actin antagonist BioAegis Therapeutics Inc US Phase Not Applicable Planned 1 2020-06-25
Atrial Fibrillation in Patients with an Implantable Cardiac Device during the COVID-19 Pandemic Atrial fibrillation, Coronavirus disease 19 infection PaceMate remote monitoring system alone, implantable cardioverter defibrillator alone, permanent pacemaker alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Adelaide US 2020-06-24 2020-06-25 ACTRN12620000692932p Phase Not Applicable Not yet recruiting 1 1000 Prof Prashanthan Sanders 2020-06-29
A clinical study of virus-neutralizing antibody therapeutic (COVID19), Kaneka in Coronavirus disease 19 infection Coronavirus disease 19 infection virus-neutralizing antibody therapeutic (COVID19), Kaneka alone Kaneka Corp Tokyo University of Science Phase Not Applicable Planned 0 2020-06-25
Comparing the user seal check and fit test between two types of N95 respirators: the Halyard N95 Particulate Filter Respirators and the ProShield N-95 masks Coronavirus disease 19 infection PortaCount machine alone, ProShield N-95 mask alone, quantitative fit test alone, user seal check alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry, Japanese Ancestry Royal Melbourne Hospital Australia 2020-06-02 2020-06-05 ACTRN12620000688987, U1111-1252-2924 Phase Not Applicable Completed 1 96 Prof Daryl Williams 2020-06-29
Effectiveness of Elman tablet on COVID-19 infection severity Coronavirus disease 19 infection Variable regimens including Elman (Simorgh Attar Neishabour Pharmaceutical) , hydroxychloroquine , lopinavir + ritonavir HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Esfarayen Faculty of Medical Sciences Iran 2020-07-09 IR.ESFARAYENUMS.REC.1399.003, IRCT20200609047707N1 Phase 3 Clinical Not yet recruiting 1 90 Eshagh Ildarabadi, Essa Tohidi, Seyed Javad Hosseini 2020-06-26
CHLORAZ: An Observational Study to Assess the Protocol for the COVID-19 Treatment in Burkina Faso Coronavirus disease 19 infection Variable regimens including azithromycin , chloroquine phosphate , hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Muraz Burkina Faso 2020-05-01 2020-12-31 CHLORAZ, IRSS-URCN-CM 001, NCT04445441 Phase Not Applicable Recruiting 2 8 Months 150 Espérance Ouédraogo, MD, Msc, Halidou Tinto, PhD, Houreratou Barry, MD, Msc, Innocent Valea, PhD, Marc Tahita, PhD 2020-06-25
KAP of New Normal Among HCW in Hospital Kuala Lumpur and Hospital Sungai Buloh Regarding COVID-19 Coronavirus disease 19 infection University of Malaya 2020-07-01 2021-06-30 55330, NMRR-20-1212-55330 Phase Not Applicable Status not specified 0 12 Months Dr Sri Viknarajan A/L Puvendran 2020-06-26
Modelling of COVID-19 in Malaysia Coronavirus disease 19 infection University of Malaya Malaysia 2020-06-22 2020-12-31 55087, NMRR-20-1208-55087 Phase Not Applicable Status not specified 1 6 Months Dr Vivek Jason a/l Jayaraj 2020-06-26
COVID-19 infected HCW Coronavirus disease 19 infection Hospital Queen Elizabeth Malaysia 2020-08-01 2021-07-31 55463, NMRR-20-1207-55463 Phase Not Applicable Status not specified 1 12 Months Dr Hor Chee Peng, Ms. Teong Win Zee 2020-06-26
Phase I Clinical Study of Recombinant Novel Coronavirus Vaccine Coronavirus disease 19 infection recombinant new coronavirus vaccine (CHO cell) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Anhui Zhifei Longcom Biopharmaceutical Co Ltd Beijing Chao-Yang Hospital, The Second Affiliated Hospital, Chongqing Medical University China 2020-06-22 2021-09-20 NCT04445194, NCV-I-HEALTHY Phase 1 Clinical Not yet recruiting 1 14 Months 50 Hong Ren, master 2020-06-30
An open-label, adaptive randomized, controlled, multicenter study to evaluate the efficacy and safety of RESP-301 plus standard of care (SOC) compared to SOC alone in hospitalized participants with COVID-19 requiring supplemental oxygen (NOCoV2) Coronavirus disease 19 infection RESP-301 alone, Standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Thirty Holdings Limited US, Spain, UK, Italy, Netherlands, France, Germany 2020-06-16 2020-002120-37, RESP301-002 Phase 2/Phase 3 Clinical Recruiting 7 300 Clinical department 2020-06-29
Measles Vaccine: Is There a Protective Role in COVID-19 Pandemic? Coronavirus disease 19 infection measles vaccine alone Ain Shams University Egypt 2020-07-01 2020-11-01 FMASU P31A/ 2020, NCT04445610 Phase Not Applicable Not yet recruiting 1 4 Months 60 Amira Al Balakosy, M.D, Amira Al Balakosy, MD 2020-06-29
A clinical study to assess the benefits of measles, mumps, rubella (MMR) vaccine as a protection against COVID-19 Coronavirus disease 19 infection MMR vaccine alone American Society for Microbiology US Phase Not Applicable Planned 1 Fidel, Noverr 2020-06-25
CO-FLOW: COVID-19 Follow-up care paths and Long-term Outcomes Within the Dutch health care system: a combined rehabilitation, pulmonary, and intensive care perspective Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Erasmus University Medical Center Rotterdam Netherlands 2020-07-01 2023-07-01 CO-FLOW, MEC 2020-0487, NL8710 Phase Not Applicable Not yet recruiting 1 36 Months 335 Majanka Heijenbrok-Kal 2020-06-29
ANTI-CO: Anticoagulation in Patients Suffering From COVID-19 Disease - The ANTI-CO Trial Coronavirus disease 19 infection, Respiratory failure bivalirudin alone Factor IIa antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hamad Medical Corp Qatar 2020-06-28 2021-03-28 ANTI-CO, MRC-05-082, NCT04445935 Phase 4 Clinical Recruiting 1 9 Months 100 Dr. Marcus Daniel Lance, Marcus Lance, MD, PhD, Nadir Kharma, MD, Stefan Roehrig, MD, MBA 2020-06-30
EPISODE-PS-COV: Head Pulse for Ischemic Stroke Detection Prehospital Study During the COVID-19 Pandemic Coronavirus disease 19 infection, Ischemic stroke Cranial accelerometry alone, Head pulse recording alone, MindRhythm Harmony alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) MindRhythm, Inc. Wayne State University 2020-07-31 2021-06-30 EPISODE-PH-COVID, EPISODE-PS-COV, NCT04445493 Phase Not Applicable Not yet recruiting 0 11 Months 250 Lisa Distenfield, Paul Lovoi, Ph.D 2020-06-25
A study to understand differences in individual risk factors for COVID-19 Coronavirus disease 19 infection Microdrop LLC Phase Not Applicable Status not specified 0 2020-06-26
Study of the Treatment and Outcomes in Critically Ill Patients With COVID-19 and High Risk of Acute Kidney Injury Coronavirus disease 19 infection, Renal injury Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Guy's & St Thomas' Hospital NHS Trust Harvard Medical School UK 2020-06-20 2021-05-31 283672, NCT04445259 Phase Not Applicable Recruiting 1 11 Months 300 Marlies Ostermann, MD, PhD, Nuttha Lumlertgul, MD, PhD 2020-06-26
Unraveling the Mechanisms of Olfactory Dysfunction in COVID-19 Coronavirus disease 19 infection, Dysomia, Olfaction disorder tissue sampling alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universitaire Ziekenhuizen Leuven Max Planck Institute for Neurological Research Belgium 2020-05-07 2020-06-30 NCT04445597, S64042 Phase Not Applicable Recruiting 1 1 Month 8 Laura Van Gerven, Laura Van Gerven, Doctor, Wout Backaert 2020-06-26
Mesenchymal Stromal Cell Therapy for Severe Covid-19 Infection Coronavirus disease 19 infection, Inflammatory disease, Viral pneumonia mesenchymal stromal cells alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Liege Belgium 2020-06-12 2022-09-30 NCT04445454, TJT2012 Phase 1/Phase 2 Clinical Recruiting 1 27 Months 20 Audrey Janssen, Benoit Misset, MD,PhD, Bernard Lambermont, MD,PhD, Gilles Darcis, MD,PhD, Michel Moutschen, MD,PhD, Nathalie Layios, MD, Yves Beguin, Yves Beguin, MD,PhD 2020-06-26
ONCOCARE-COV: Oncology Care Pathway's Modifications Impact During COVID-19 Pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Reims France 2020-05-01 2020-12-31 2020AO001*, NCT04445870, ONCOCARE-COV Phase Not Applicable Recruiting 1 8 Months 100 Damien JOLLY, Mathias BRUGEL 2020-06-30
SCIL-COV19 PK/PD: Does subcutaneously administered anakinra achieve good penetration in blood and result in reduced inflammation in patients with SARS-CoV-19? Coronavirus disease 19 infection, Inflammatory disease anakinra alone Type I IL-1 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Manchester UK 2020-05-20 2020-001636-95, 282110, SCIL-COV19 PK/PD Phase 2 Clinical Recruiting 1 40 Tim Felton 2020-06-26
Antiphospholipid Antibody (APLA) level in COVID-19 Cases Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) KIMS Hospital India 2020-08-01 CTRI/2020/06/026118 Phase Not Applicable Not yet recruiting 1 80 Dr Rajlaxmi Sarangi 2020-06-26
CO-HOST: COVID-19 Household Transmission Study Coronavirus disease 19 infection biological sampling alone Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of North Carolina North Carolina Translational and Clinical Sciences Institute US 2020-04-29 2020-12-31 20-0982, 550KR242023, CO-HOST, NCT04445233 Phase Not Applicable Recruiting 1 8 Months 400 Carla Cerami, MD, PhD, Christopher Basham, BS, MSc, David Wohl, MD, Jessica Lin, MD, MSCR, Jonathan Juliano, MD, MSPH 2020-06-26
Pediatrics HOT COVID-19 Database in NY Tristate Coronavirus disease 19 infection, Neoplasm, Neurological disease, Sickle cell anemia, Stem cell transplantation Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Columbia University US 2020-04-30 2022-05-01 AAAT0268, NCT04445402 Phase Not Applicable Recruiting 17 24 Months 1500 Alex Chou, MD, Alissa Kahn, MD, Andrea Orsey, MD, Archana Sharma, Jean Sosna, MS RN, Jeffrey Lipton, MD, Jennifer Krajewski, Jennifer Levine, MD, Jessica Hochberg, MD, Joanna Pierro, MD, Katie Devine, Laura Hogan, MD, Marianna DeBenedictis, MD, Nina Kadan-Lottick, MD, Pallavi Madhusoodhan, MD, Prakash Satwani, MD, Stephen Roberts, Steven Halpern 2020-06-26
COVID-VENT: Respiratory Mechanics and Gas Exchange in Patients With COVID-19 and Hypoxemic Acute Respiratory Failure Coronavirus disease 19 infection, Hypoxia, Respiratory failure gas exchange measurement alone, respiratory mechanics measurement alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) IM Sechenov Moscow Medical Academy Russian Federation 2020-05-01 2020-08-31 COVID-VENT, COVID-VENT, NCT04445961 Phase Not Applicable Recruiting 1 4 Months 70 Andrey I Yaroshetskiy, Dr.Med.Sc., Mikhail E Politov, PhD, Pavel V Nogtev, PhD, Sergey N Avdeev, Prof, Yury D Sorokin, PhD 2020-06-26
Treatment with Omega-3 polyunsaturated fatty acids in COVID-19 patients: A single-blind, randomized, placebo-controlled, feasibility study Coronavirus disease 19 infection, Inflammatory disease Omegaven alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Karolinska University Hospital Swedish Heart Lung Foundation, Swedish Research Council Sweden 2020-05-29 2020-002293-28 Phase 2 Clinical Recruiting 1 20 Co-ordinating investigator 2020-06-26
Phase II, randomized, controlled, open-label study of Pegylated IFN alfa-2b with SARS-CoV-2 Coronavirus disease 19 infection Pegylated IFN alfa-2b alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Zydus-Cadila Group India 2020-07-10 CTRI/2020/06/026087, PEGI.20.002 Phase 2 Clinical Not yet recruiting 1 40 Dr Anuja Pandit, Dr Kevinkumar Kansagra 2020-06-26
An interventional study to access the effect of Homoeopathic medicine Arsenicum album 30 C as a prohylaxis in high risk population exposed to COVID-19 Coronavirus disease 19 infection Arsenicum album 30 C alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush India 2020-06-26 CTRI/2020/06/026056 Phase 3 Clinical Not yet recruiting 1 5000 Dr Tapan Nath, Prof PK Goswami 2020-06-26
CovidImmunEye: Immune Status SARS-CoV-2 in a Sample of a Tertiary Eye Health Centre Coronavirus disease 19 infection ELISA test alone, Rapid test alone Healthy volunteers accepted University Hospital Tubingen Klinikum rechts der Isar der Technischen Universitaet Muenchen Germany 2020-05-13 2020-08-31 292/2020BO2, CovidImmunEye, NCT04446338 Phase Not Applicable Recruiting 2 3 Months 300 Focke Ziemssen, Focke Ziemssen, MD, Tarek Bayyoud, MD 2020-06-26
An interventional study to access the effect of Ayurvedic medicine ASA-20 as a prohylaxis in high risk population exposed to COVID-19 Coronavirus disease 19 infection ASA-20 alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush India 2020-06-26 CTRI/2020/06/026055 Phase 3 Clinical Not yet recruiting 1 5000 Dr Sikha Lekharu, Prof Dr P K Goswami 2020-06-26
A phase II, randomized, controlled, multicenter to evaluate the safety, tolerability, and effectiveness of OT-101 in combination with standard of care (SoC) in hospitalized COVID-19 patients Coronavirus disease 19 infection standard of care (SoC) alone, trabedersen alone TGFB2 gene inhibitor Mateon Therapeutics Inc IQVIA Holdings Inc Phase 2 Clinical Planned 0 2020-06-25
PARTISAN: Prasugrel in Severe COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia prasugrel alone P2Y12 purinoceptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Ospedaliera Universitaria Integrata Di Verona Universita degli Studi di Milano Italy 2020-07-31 2021-01-31 MGI-COVID-19-PRASUGREL, NCT04445623, PARTISAN Phase 3 Clinical Not yet recruiting 1 6 Months 128 Marco Cattaneo, Professor, Pietro Minuz, Professor 2020-06-29
ILOCOVID: Inhaled Iloprost for Suspected COVID-19 Respiratory Failure Coronavirus disease 19 infection, Hypoxia, Respiratory failure iloprost (inhaled nebulizer formulation, pulmonary hypertension), Bayer Schering/Actelion alone PGI2 agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hamad Medical Corp Qatar 2020-05-23 2021-05-31 ILOCOVID, MRC-05-026, NCT04445246 Phase 2 Clinical Recruiting 1 12 Months 40 Ali AitHssain, MD, Nadir Kharma, MD 2020-06-26
A Study of LAM-002A for the Prevention of Progression of COVID-19 Coronavirus disease 19 infection apilimod dimesylate (capsule, B-cell non-Hodgkins lymphoma/Chronic lymphocytic leukemia/amyotrophic lateral sclerosis), AI Therapeutics alone FYVE finger phosphoinositide kinase inhibitor, IL-12 receptor antagonist, IL-23 antagonist, Transcription factor EB stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AI Therapeutics Yale University US 2020-06-29 2021-01-31 LAM-002A-CVD-CLN01, NCT04446377 Phase 2 Clinical Not yet recruiting 1 7 Months 142 Charles Dela Cruz, MD, Ph.D, Peter Young, PhD 2020-06-26
Ivermectin in Treatment of COVID-19 Coronavirus disease 19 infection ivermectin alone, standard of care alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Zagazig University Egypt 2020-05-31 2020-08-15 NCT04445311, ZU-IRB-6151/31-5-2020 Phase 2/Phase 3 Clinical Recruiting 1 2 Months 100 Waheed Shouman, Waheed Shouman, MD 2020-06-26
VIRCO: An Adaptive, Randomized, Placebo-Controlled, Phase II Trial of Antivirals for COVID-19 Infection Coronavirus disease 19 infection favipiravir alone, usual standard of care alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bayside Health 2020-07-31 2020-11-30 66223, NCT04445467, VIRCO Phase 2 Clinical Not yet recruiting 0 4 Months 190 James McMahon, Janine Roney 2020-06-26
Short Term Corticosteroids in SARS-CoV2 Patients Coronavirus disease 19 infection, Hypoxia, Viral pneumonia dexamethasone alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Miriam Hospital US 2020-04-01 2020-05-31 20-027, NCT04445506 Phase Not Applicable Completed 1 2 Months 50 Kwame Dapaah-Afriyie, MD 2020-06-26
Experimental Expanded Access Treatment With Convalescent Plasma for the Treatment of Patients With COVID-19 Coronavirus disease 19 infection, Respiratory failure convalescent COVID-19 plasma alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Massachusetts, Worcester US H000020420, NCT04445207 Phase Not Applicable Recruiting 1 Cara Gregoire, Jonathan Gerber, Jonathan Gerber, MD, Principal Investigator 2020-06-26
A study to improve the resistance against Covid-19 illness with the help of Homoeopathic remedies Coronavirus disease 19 infection homoeopathic medicine therapy alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Father Muller Homoeopathic Medical College India 2020-07-01 CTRI/2020/06/026045 Phase 3 Clinical Not yet recruiting 1 800 Dr Dilip B Dikshit, Dr M K Kamath 2020-06-26
Oral Fluid Sars-CoV-2 Ab Rapid test Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Asian Healthcare Foundation India 2020-07-04 CTRI/2020/06/026044, OFST19 Phase Not Applicable Not yet recruiting 1 100 Naveen Chander Reddy P, Sasikala Mitnala, Vishnupriya Rao Paturi 2020-06-26
DAMPEN COVID: Phase II Trial Using rhDNase to Reduce Mortality in COVID-19 Patients With Respiratory Failure Coronavirus disease 19 infection, Respiratory failure dornase alfa alone Deoxyribonuclease I stimulator, Deoxyribonuclease stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of South Alabama US 2020-04-28 2020-07-31 DAMPEN COVID, NCT04445285, USAH 1002 000 Phase 2 Clinical Recruiting 1 3 Months 44 Jon D Simmons, M.D., Jon Simmons, Jon Simmons, M.D., Wendy Blount, RN, MSN 2020-06-26
The Effect of Inspiratory muscle training in patients with COVID-19 Coronavirus disease 19 infection Inspiratory muscle training device alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Shahid Beheshti University of Medical Sciences, Laser Application in Medical Sciences Research Center Iran 2020-07-22 IR.SBMU.NRITLD.REC.1399.088, IRCT20200611047727N1 Phase Not Applicable Not yet recruiting 1 40 Atefeh Fakharian, Maryam Mirenayat, Saba Karimzade 2020-06-26
HERD: Protection of Health Workers Against COVID-19 Coronavirus disease 19 infection, Respiratory disease Previfenon alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) MELISA Institute Genomics & Proteomics Research SpA Universidad Austral De Chile Chile 2020-07-30 2020-11-30 HERD, MEL109042020, NCT04446065 Phase 2/Phase 3 Clinical Not yet recruiting 1 4 Months 524 Cristian Vargas, MD, Elard Koch, PhD, Head of Reserach, Elard S Koch, PhD, Miguel A Bravo, MPH 2020-06-26
A diagnostic study comparing different tests for the diagnosis of COVID-19 Coronavirus disease 19 infection RT-PCR alone, nasopharyngeal swab test alone, serological test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) IRCCS Sacro Cuore Don Calabria hospital Ministero della Salute Italy 2020-02-26 2020-05-25 ISRCTN13990999 Phase Not Applicable Completed 1 3 Months 400 Prof Bisoffi 2020-06-26
Diagnostic Value of New COVID-19 Antibodies Testing Among Laboratory Healthcare Workers Coronavirus disease 19 infection Covid-19 antibody testing alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Assiut University Egypt 2020-07-01 2021-09-01 COVID-19 ANTIBODIES TESTING, NCT04445415 Phase Not Applicable Not yet recruiting 1 14 Months 250 Azza Ezzeldin, Professor, Samar Salah Eldin, Samar Salah Eldin Abdelrahman Sultan 2020-06-29
Anti-Androgen Treatment for COVID-19 Alopecia, Coronavirus disease 19 infection Variable regimens including azithromycin , dutasteride , ivermectin 5-Alpha-reductase inhibitor, 5-Alpha-reductase-1 inhibitor, 5-Alpha-reductase-2 inhibitor, Chloride channel modulator Male, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Applied Biology Inc Corpometria Institute, Warren Alpert Medical School of Brown University Brazil 2020-06-26 2021-01-31 AB-DRUG-SARS-004, NCT04446429 Phase 2 Clinical Not yet recruiting 1 7 Months 254 Andy Goren, MD, Carlos G. Wambier, Carlos Wambier, MD, Flavio A Cadegiani, MD, John McCoy 2020-06-29
COVID-19 (SARS-CoV-2) in Urine and Semen Coronavirus disease 19 infection, Genital tract infection PCR test alone Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universita degli Studi di Firenze Azienda Ospedaliera Careggi Italy 2020-07-12 2020-08-12 17104_OSS/2020, NCT04446169 Phase Not Applicable Recruiting 1 1 Month 50 Alberto Antonelli, MD, Alessandro Bartoloni, Prof, Arcangelo Sebastianelli, MD, Claudia Zaccaro, MD, Filippo Lagi, MD, Gian Maria Rossolini, Prof, Mauro Gacci, MD, Saverio Giancane, MD, Sergio Serni, Prof, Silvia Benemei, PhD, Simona Pollini, MD, Simone Morselli, Simone Morselli, MD 2020-06-26
ECMO-SL-CoV-2: Bicentric Study on the Use of ECMO-VV or VA for Severe ARDS Associated With SARS-CoV-2 Coronavirus disease 19 infection, Respiratory distress syndrome veno-arterial extracorporeal membrane oxygenation therapy alone, veno-venous extracorporeal membrane oxygenation therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg France 2020-06-18 2020-07-18 7904, ECMO-SL-CoV-2, NCT04446286 Phase Not Applicable Recruiting 1 1 Month 50 Anne OLLAND, MD, PhD, Bart MEYNS, MD, PhD, Jean-Philipe MAZZUCOTELLI, MD, PhD, Leen VERCAEMST, MD, Marc PUYRAVEAU, MD, Marion VILLARD, MD, Pierre-Emmanuel FALCOZ, MD, PhD, Saïd CHAYER, PhD, HDR 2020-06-26
OPV as Potential Protection Against COVID Coronavirus disease 19 infection COVID-19 protection advice alone, bivalent oral polio vaccine (GSK) alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bandim Health Project Guinea-Bissau 2020-07-31 2021-06-30 77/CNES/INASA/2020, NCT04445428 Phase 4 Clinical Not yet recruiting 1 11 Months 3400 Ane Fisker, MD, PhD 2020-06-29
A Study of Cell Therapy in COVID-19 Subjects With Acute Kidney Injury Who Are Receiving Renal Replacement Therapy Coronavirus disease 19 infection, Renal injury SBI-101 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sentien Biotechnologies 2020-08-31 2021-07-31 NCT04445220, SBI-101-02 Phase 1/Phase 2 Clinical Not yet recruiting 0 11 Months 24 Brian Miller 2020-06-26
PLATINA trial: Plasma therapy in corona patients (Severe COVID-19) Coronavirus disease 19 infection Convalscent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Government Medical College, Nagpur India 2020-06-25 CTRI/2020/06/026123, PLATINA trial Phase 2 Clinical Not yet recruiting 16 472 Dr Anita Bandichhode, Dr Anita Basavaraj, Dr Baba Yelke, Dr D P Bhurke, Dr Deepak Shejwal, Dr Mahendrakumar V Bansode, Dr Maroti Karale, Dr Minakshi Bhattacharya, Dr Prasad Potdukhe, Dr Radha Munje, Dr Rohidas Borse, Dr Sanjay Chawhan, Dr Sheshrao S Chavan, Dr Sunita Ade, Dr Sushant Meshram, Dr Vidya Nagar, Dr Vijay Gaikwad 2020-06-26
Safety and Immunogenicity Study of GX-19, a COVID-19 Preventive DNA Vaccine in Healthy Adults Coronavirus disease 19 infection GX-19 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Genexine Co Ltd South Korea 2020-06-17 2022-06-17 GX-19-HV-001, NCT04445389 Phase 1/Phase 2 Clinical Recruiting 1 24 Months 190 Jun Yong Choi, MD, JungWon Woo, Ph.D., Wonjin Lee, B.S., Yoon-Jeong Choi, M.S., Young Goo Song, MD 2020-06-27
To Understand Knowledge and Compliance of Hydroxychloroquine Prophylaxis among Health Care Workers during COVID-19 pandemic Coronavirus disease 19 infection hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Sanjay Gandhi Postgraduate Institute of Medical Sciences India 2020-07-04 CTRI/2020/06/026121 Phase Not Applicable Not yet recruiting 1 175 Dr Mohan Gurjar 2020-06-26
Changes in smell and taste as clinical presentation in patients with mild to moderate Coronavirus disease Coronavirus disease 19 infection, Dysomia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kalinga Institute of Medical Sciences India 2020-06-24 CTRI/2020/06/026122 Phase Not Applicable Not yet recruiting 1 250 Dr Pradipt Ranjan Sahoo 2020-06-26
Multicenter, open, prospective, randomized, comparative study to study the safety and efficacy of the drug Remdeform (INN: remdesivir), lyophilisate for the preparation of a solution for intravenous administration, 100 mg (Farmasintez JSC, Russia) as part of complex therapy with patients hospitalized with COVID-19 Coronavirus disease 19 infection remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Pharmasyntez Russian Federation 2020-06-22 2021-01-01 REMVR-2020/I Phase 3 Clinical Status not specified 16 6 Months 300 2020-06-25
Clinical Improvement and COVID-19 Pneumonia Coronavirus disease 19 infection, Tachypnea, Viral pneumonia ozone autohemotherapy alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) L'Institut d Investigacio Biomedica de Girona Spain 2020-03-20 2020-05-26 COVID NETWORKING GROUP, NCT04444531 Phase Not Applicable Completed 1 2 Months 18 Marc Vives 2020-06-25
AGMFMSS: Alterations of Gut Microbiome in the Frontline Medical Staff Under the Stress Acute stress disorder, Coronavirus disease 19 infection 16S rRNA sequencing alone, PCR alone, fecal sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) The First Affiliated Hospital of Xi'an Jiaotong University China 2020-06-22 2020-08-30 AGMFMSS, NCT04443075, XJTU1AF2020LSK-022 Phase Not Applicable Recruiting 1 2 Months 180 Fengjie Gao, M.M., Xiancang Ma, M.D. 2020-06-26
REHCOVER: Reassessement After Hospitalization for Sars-COV-2 Disorder Cardiovascular disease, Coronavirus disease 19 infection, Fibrosis, Liver disease, Metabolic disorder, Neurological disease, Psychiatric disorder, Renal disease, Respiratory failure Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2020-06-23 2021-06-25 NCT04443257, RECHMPL20-340, REHCOVER Phase Not Applicable Not yet recruiting 1 12 Months 200 Camille ROUBILLE, MD, Camille Roubille, MD 2020-06-26
COVID-19 Vaccine (ChAdOx1 nCoV-19) Trial in South African Adults With and Without HIV-infection Coronavirus disease 19 infection, Respiratory tract infection AZD-1222 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Witwatersrand Bill & Melinda Gates Foundation, Medical Research Council Of South Africa MRC, University of Oxford South Africa 2020-06-30 2021-12-31 CHADOX1 NCOV-19-ZA-PHI/II, NCT04444674, PACTR202006922165132 Phase 1/Phase 2 Clinical Not yet recruiting 6 18 Months 2000 Clare L Cutland, MBBCH, PhD, Erica Lazarus, MBCHB, Karishma Naidoo, Keertan Dheda, MD, PhD, Lee Fairlie, MD, Shabir A Madhi, MD, PhD, Shaun Barnabas, MD, PhD, Sherman Padayachee, MD, Thabile Msomi 2020-06-26
Efficacy and Safety of Anti-HCV Drugs in the Treatment of COVID-19 Coronavirus disease 19 infection Variable regimens including daclatasvir , hydroxychloroquine , sofosbuvir Hepatitis C virus NS5B polymerase inhibitor, Hepatitis C virus protein NS5A inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Cairo University Egypt 2020-07-31 2020-12-31 CUKA-003, NCT04443725 Phase 2/Phase 3 Clinical Not yet recruiting 1 5 Months 100 Gamal Esmat 2020-06-26
Characterizing the Perioperative Epidemiology of SARS-CoV-2 (COVID-19) Spread for Quality Improvement of Perioperative Infection Control Program Coronavirus disease 19 infection PathTrac (RDB Bioinformatics) collection kit alone, UV-C (Helios, Surfacide) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Iowa US 2020-07-01 2020-08-31 202005391, NCT04443803 Phase Not Applicable Not yet recruiting 1 2 Months 9 Randy Loftus, Randy W Loftus, MD 2020-06-24
Effects of COVID-19-Induced Deconditioning After Long-term High-Intensity Resistance Exercise Coronavirus disease 19 infection, Osteopenia, Osteoporosis, Sarcopenia high-intensity resistance exercise alone Male, Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Erlangen-Nurnberg Medical School Friedrich-Alexander-Universitaet Erlangen-Nuernberg Germany 2020-06-10 2020-12-31 FROST-FU, NCT04444661 Phase Not Applicable No longer recruiting 1 6 Months 21 Wolfgang Kemmler, PhD 2020-06-24
Preeclampsia-like Syndrome Induced by COVID-19: Is it a Real Public Health Issue in Pregnancy During the Pandemic? Coronavirus disease 19 infection, Pre-eclampsia PCR test alone, lung ultrasound alone Female, Young Adults (18-44 yrs) Zeynep Kamil Maternity and Pediatric Research and Training Hospital Turkey 2020-03-15 2020-07-10 70/2020, NCT04443140 Phase Not Applicable Recruiting 1 3 Months 100 Resul Karakus, MD, Resul Karakuş 2020-06-30
Predictors of Mental Well-being During the COVID-19 Pandemic Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oslo Modum Bad Norway 2020-06-22 2020-07-13 NCT04443699, REK125510-12 Phase Not Applicable Not yet recruiting 3 4000 Hoffart Hoffart, PhD, Omid Ebrahimi, Double PhD Candidate, Sara Ebling, Cand.psychol. stud., Sverre Urnes Sverre Urnes, PhD 2020-06-25
Glycine Supplement for Severe COVID-19 Coronavirus disease 19 infection, Viral pneumonia glycine alone, habitual treatment alone Instituto Nacional de Enfermedades Respiratorias Mexico 2020-06-22 2021-06-30 C40-20, NCT04443673 Phase Not Applicable Recruiting 1 12 Months 82 Alejandra R Báez-Saldaña, MD, Cristóbal Guadarrama-Pérez, MD, David Ibarra-Villarreal, MD, Jaime Chávez-Alderete, PhD, Justino Regalado-Pineda, MD, Mario H Vargas, MSc, Mario H. Vargas, MD, MSc 2020-06-25
Information Sources and Their Relationship to Depressive and Anxiety Symptoms During the COVID-19 Pandemic: A Network Study Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oslo Modum Bad Norway 2020-06-22 2020-07-13 NCT04444336, REK125510-16 Phase Not Applicable Not yet recruiting 2 4000 Asle Hoffart, PhD, Omid Ebrahimi, Double PhD Candidate, Omid V. Ebrahimi, Double PhD Candidate, Sverre Urnes Johnson, PhD 2020-06-25
A phase I clinical trial of SARS-CoV-2 protein subunit vaccine for COVID-19 Coronavirus disease 19 infection SARS-CoV-2 protein subunit vaccine (COVID-19), Chongqing Zhifei Biological Products/ Institute of Microbiology, Chinese Academy of Sciences alone COVID19 Spike glycoprotein modulator Institute of Microbiology, CAS Anhui Zhifei Longcom Biopharmaceutical Co Ltd China Phase 1 Clinical Not yet recruiting 1 2020-06-24
Mesenchymal Stem Cell Infusion for COVID-19 Infection Coronavirus disease 19 infection, Multiple organ failure, Respiratory failure, Septic shock, Viral pneumonia Standard care alone, mesenchymal stem cells alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Armed Forces Bone Marrow Transplant Center Pakistan 2020-05-01 2020-09-30 NCT04444271, NIBMT-MSC-COVID-2020 Phase 2 Clinical Recruiting 2 5 Months 20 Xanab Akram, Zaineb Akram, xanab akram 2020-06-30
Antibody Responses in Contacts of COVID-19 Patients Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assiut University Egypt 2020-06-15 2020-09-30 ASSIUT13, NCT04444310 Phase Not Applicable No longer recruiting 1 3 Months 100 2020-06-25
BIBS: Brain Imaging in Babies Study Attention deficit hyperactivity disorder, Autism, Central nervous system development disorder, Coronavirus disease 19 infection MRI alone, traditional behavioural assessments alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) King's College London Business Ltd UK 2013-04-05 2023-12-31 BIBS, IRAS: 108997, REC 12/LO/2017, NCT04443179 Phase Not Applicable Recruiting 1 128 Months 790 Dr Grainne McAlonan, Gráinne McAlonan, PhD 2020-06-25
Sequelae of Sars-CoV-2 Infections Coronavirus disease 19 infection, Viral pneumonia computer tomography alone, echocardiography alone, electrocardiography alone, pneumologic test alone, spiroergometry alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Giessen Germany 2020-05-20 2023-12-31 NCT04442789, SECOV Phase Not Applicable Recruiting 1 43 Months 30 Khodr Tello, MD, Ulrich Matt, MD, PhD 2020-06-26
Loneliness During Strict and Lifted Social Distancing Protocols Against the COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Modum Bad University of Oslo Norway 2020-06-22 2020-07-13 802810-1, NCT04444115 Phase Not Applicable Not yet recruiting 2 10084 Asle Hoffart, Asle Hoffart, PhD, Omid Ebrahimi, Cand Psychol, Sverre Urnes Johnson, PhD 2020-06-26
The effects of self-care cellphone application on stress, anxiety and depression among admitted patients with COVID-19 Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression mobile-based application alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mashhad University of Medical Sciences Iran 2020-04-26 IR.MUMS.REC.1399.118, IRCT20170922036314N4 Phase 3 Clinical Recruiting 1 112 Dr. Mahnaz Amini, Shokoufeh Aalaei, aalaei shokoufeh 2020-06-25
Status and Predictors of Mental Health Symptoms Among Migrants and Refugees During the COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oslo Modum Bad Norway 2020-06-22 2020-07-13 NCT04443764, REK125510 (8) Phase Not Applicable Not yet recruiting 2 287 Asle Hoffart, PhD, KariAnne Vrabel, PhD, Omid Ebrahimi, Mr, Sverre Urnes Johnson, Sverre Urnes Johnson, PhD 2020-06-25
COST-HD: Effect Of Covid-19 On Mental Health In Syrian And Turkish Maintenance Hemodialysis Patients Coronavirus disease 19 infection, Depression Beck Depression Inventory (BDI) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sisli Etfal Hospital Turkey 2020-04-17 2020-05-01 200620, COST-HD, NCT04444557 Phase Not Applicable Completed 1 97 Mustafa Sevinc, MD, Nuri Baris Hasbal 2020-06-26
Screening for Patients Admitted to Ain-Shams University Hospitals for SARS-COV-2 (COVID19) Coronavirus disease 19 infection RT-PCR test alone Ain Shams University Egypt 2020-05-29 2021-12-01 FMASU P29 /2020, NCT04443712 Phase Not Applicable Recruiting 1 18 Months 1900 Fatma Soliman E Ebeid, Samia Girgis 2020-06-26
Do Network Centrality Predict Overall Depression Symptom Reduction With Lifting of Social Distancing Protocols? Coronavirus disease 19 infection, Depression social distancing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Modum Bad University of Oslo Norway 2020-06-22 2020-07-13 802810-2, NCT04444713 Phase Not Applicable Not yet recruiting 2 10084 Asle Hoffart, PhD, Omid Ebrahimi, CandPsychol, Sverre Urnes Johnson, PhD 2020-06-26
Conjunctival Swab versus Nasopharyngeal Swab in Patients With COVID-19 Coronavirus disease 19 infection conjunctival swab test alone, nasopharyngeal swab test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medizinische Universität Innsbruck Austria 2020-06-17 2021-03-31 1104/2020, NCT04444596 Phase Not Applicable Recruiting 1 9 Months 100 Claus Zehetner, Dr, Claus Zehetner, Dr., Teresa Rauchegger, Dr, Teresa Rauchegger, Dr. 2020-06-26
INTENSIVE: Registry on NEN Patients and COVID-19 Coronavirus disease 19 infection, Neuroendocrine tumor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) European Institute of Oncology Italy 2020-06-15 2020-12-15 IEO-1291, INTENSIVE, NCT04444401 Phase Not Applicable Recruiting 1 6 Months 50 Cristina Mazzon, Ph.D., Darina Tamayo, PharmSC., Darina Tamayo, PharmSc, Francesca Spada, MD, PhD, Lorenzo Gervaso, MD, Nicola Fazio, M.D., Ph.D., Nicola Fazio, MD, PhD 2020-06-25
RAPID-BRAZIL: A Pragmatic, Randomized, Controlled Trial of Therapeutic Anticoagulation Versus Standard Care as a Rapid Response to COVID-19 Pandemic Coronavirus disease 19 infection, Thromboembolism enoxaparin sodium alone Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo St Michaels Hospital, University of Vermont Medical Center Brazil 2020-06-25 2020-12-31 CAAE: 33109220.7.0000.0068, NCT04444700, RAPID-BRAZIL Phase 3 Clinical Recruiting 1 6 Months 462 Elnara M Negri, MD, PhD, Hassan Rahhal, MD, Heraldo P de Souza, MD, PhD, Peter Juni, MD, FESC 2020-06-25
LapCoVIDSurg: COVID 19: Is SARS-CoV-2 Contaminating Surgical Aerosols From Laparoscopy and Open Abdominal Surgery? Coronavirus disease 19 infection GeneXpert (Roche) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Basel Switzerland 2020-08-31 2021-02-28 052020, LapCoVIDSurg, NCT04444687 Phase Not Applicable Not yet recruiting 1 6 Months 20 Fabian Haak, Marco von Strauss und Torney 2020-06-26
Chloroquine Phosphate Prophylactic Use in Health Personnel Exposed to COVID-19 Patients Coronavirus disease 19 infection Plasmodin (chloroquine phosphate) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) ISSSTE Centro Medico Nacional 20 de Noviembre Mexico 2020-06-22 2020-11-30 01, NCT04443270 Phase 1 Clinical Not yet recruiting 1 5 Months 200 Alberto H De la Vega-Bravo, MD, Alejandro Alanis-Vega, MD, Carlos A Delgado-Quintana, MD, Eduardo Soei-Sarmiento, BsC, Fedra Irazoque-Palazuelos, MD, Fidel Cerda-Tellez, MD, Joel Vargas-Hernández, MD, Juan A Pineda-Juárez, PhD, Juan A Suárez-Cuenca, MD, PhD, Luis Montiel-López, MD, MSc, Maribel Santosbeña-Lagunes, MD, Maricela Escarela-Serrano, MD, María C Méndez-Vidrio, MD, Mireya Rodríguez-Martínez, MD, Paul Mondragón-Terán, PhD, Ricardo P Vázquez-Alvarado, MD, Sandra Muñoz-López, MD, MSc, Sofía L Alcaraz-Estrada, PhD 2020-06-25
Nitric Oxide Releasing Solution to Treat and Prevent Exacerbation of Mild COVID-19 Infection Coronavirus disease 19 infection nitric oxide-based antiviral formulation (nasal spray/nasopharyngeal flush, COVID-19), Sanotize Research and Development alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) SaNOtize Research and Development Corp Canada 2020-09-30 2021-07-31 COVID-IND-01, NCT04443868 Phase 2 Clinical Not yet recruiting 1 10 Months 300 Chris Miller, Ph.D., Jeremy Road, MD 2020-06-26
IMPReSSION: Improving Cardiovascular Risk Stratification Using T1 Mapping in General population Cardiovascular disease, Coronavirus disease 19 infection T1 mapping alone, T2 mapping alone, cardiovascular magnetic resonance alone, gadobutrol plus gadolinium Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johann Wolfgang Goethe-Universitat Frankfurt am Main Johannes Gutenberg Universitat Mainz, Kerckhoff-Klinik GmbH, University Hospital Ulm Germany 2016-11-15 2026-11-15 IMPRESSION STUDY, IMPReSSION, NCT04444128 Phase Not Applicable Recruiting 3 120 Months 3000 Andreas Rolf, MD, Franziska Weis, Philip Wenzel, MD, Valentina O Puentmann, MD, PhD, Valentina Puentmann 2020-06-26
Insomnia After the COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection, Depression, Insomnia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oslo Modum Bad Norway 2020-06-22 2020-07-13 NCT04443361, REK125510 (7) Phase Not Applicable Not yet recruiting 2 5000 Asle Hoffart, PhD, Omid Ebrahimi, Mr, Sverre Urnes Johnson, PhD 2020-06-26
Phase I/II study of COVID-19 DNA vaccine (AG0301-COVID19) in healthy adults Coronavirus disease 19 infection AG-0301-COVID19 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) AnGes MG Inc Japan Medical Association Japan 2020-06-25 2021-07-31 JapicCTI-205328 Phase 1/Phase 2 Clinical Not yet recruiting 1 13 Months 30 Anges Co., Ltd. 2020-06-29
SeroCoV-HUS: Seroprevalence of SARS-CoV-2 in Strasbourg University Hospital, Strasbourg, France (COVID-19) Coronavirus disease 19 infection COVID-19 BSS reference SW40005 diagnostic kit (Biosynex) alone, EDI Novel Coronavirus COVID-19 ELISA IgG kit (Epitope Diagnostics Inc) alone, ELISA alone, lateral flow assay-immuno-chromatographic test (LFA-ICT) alone, serological test alone, seroneutralization test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg France 2020-04-17 2021-08-31 7782, NCT04441684, SeroCoV-HUS Phase Not Applicable Recruiting 1 16 Months 1800 Aleksandra NADAJ-PAKLEZA, MD, Catherine MUTTER, MD, David REY, MD PhD, Jean-Baptiste CHANSON, MD, Jérôme DE SEZE, MD PhD, Laurent KREMER, MD, Livia LANOTTE, MD, Maria GONZALEZ, MD PhD, Maria PARTISANI, MD, Marie MIELCAREK, MD, Marie-Aude SPITZ, MD, Marie-Céline FLEURY, MD, Nathalie PHILIPPI, MD, Nicolas COLLONGUES, MD, Nicolas LEFEBVRE, MD, Samira FAFI-KREMER, MD PhD, Yves HANSMANN, MD PhD 2020-06-25
Therapeutic Plasma Exchange for COVID-19-associated Hyperviscosity Coronavirus disease 19 infection, Vascular disease frozen plasma alone, therapeutic plasma exchange alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Emory University US 2020-07-31 2020-10-31 NCT04441996, STUDY00000949 Phase 4 Clinical Not yet recruiting 3 3 Months 20 Cheryl Maier, MD, PhD 2020-06-25
Convalescent Plasma Therapy on Critically-ill Novel Coronavirus (COVID-19) Patients Coronavirus disease 19 infection, Dyspnea, Viral pneumonia convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Alkarkh Health Directorate-Baghdad Iraq 2020-04-03 2020-06-01 CPT-COVID-19, NCT04441424 Phase 2 Clinical Completed 1 1 Month 49 Ahmed S Abdulamir, PhD 2020-06-27
Convalescent Plasma as a Possible Treatment for COVID-19 Coronavirus disease 19 infection convalescent plasma alone, convalescent plasma plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Illinois US 2020-05-05 2021-05-05 2020-0441, NCT04442191 Phase 2 Clinical Recruiting 1 12 Months 50 Jesica A Herrick, MD, Jesica A Herrick, MD, MS, Jesica Herrick, Mahesh Patel, MD, Richard Novak, MD, Sally Campbell-Lee, MD 2020-06-26
A short-term follow-up study to assess the effect of SARS-CoV-2 total antibody assay in dialysis patients with Covid-19 Coronavirus disease 19 infection SARS-CoV-2 total antibody assay (Siemens Healthineers) alone Ascend Clinical, Stanford University School of Medicine US 2020-07-31 Phase Not Applicable Planned 1 30000 Shuchi Anand, MD 2020-06-25
Factors Associated With Adherence to Hygiene-related Behaviors and Viral Mitigation Protocols During the COVID-19 Pandemic Coronavirus disease 19 infection hygiene-related behavior alone, viral mitigation protocol alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oslo Modum Bad Norway 2020-06-22 2020-07-13 NCT04442217, REK125510-11 Phase Not Applicable Not yet recruiting 2 4000 Asle Hoffart, PhD, Omid V. Ebrahimi, Double PhD Candidate, Sverre Urnes Johnson, PhD 2020-06-24
Assessment of Lung Inflammation With FDG PET/CT in COVID-19 Coronavirus disease 19 infection, Lung inflammation FDG alone, computerized tomography alone, positron emission tomography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Princesse Grace Monaco 2020-03-27 2020-05-27 NCT04441489, PET-COVID Phase Not Applicable Completed 1 2 Months 13 2020-06-23
Spatial-temporal modelling, covid-19 Coronavirus disease 19 infection spatial-temporal modelling alone Universiti Kebangsaan Malaysia Malaysia 2020-07-01 2020-12-31 54919, NMRR-20-1178-54919 Phase Not Applicable Status not specified 1 6 Months Prof. Mohd Talib Latif 2020-06-25
COVID-19 Serosurvey Coronavirus disease 19 infection National Institutes of Health Malaysia Malaysia 2020-08-01 2020-10-30 55133, NMRR-20-1166-55133 Phase Not Applicable Not yet recruiting 1 2 Months Dr Chong Zhuo Lin, Mr. Mohd Hatta Bin Abdul Mutalip 2020-06-25
Impact survey Coronavirus disease 19 infection Sultanah Nur Zahirah Hospital Malaysia 2020-07-01 NMRR-20-1160-55260, NR 2020 55260 Phase Not Applicable Status not specified 1 DR nandinii a/p ramasenderan 2020-06-24
Tolerability, Safety, Pharmacokinetic Profile and Immunogenicity of a Recombinant Humanized Anti-SARS-CoV-2 Monoclonal Antibody (JS-016) for Injection in Chinese Health Subjects Coronavirus disease 19 infection JS-016 alone COVID19 Spike glycoprotein inhibitor Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Asian Ancestry Eli Lilly & Co, Shanghai Junshi Biosciences Co Ltd China, US 2020-06-05 2020-12-11 JS016-001-I, NCT04441918 Phase 1 Clinical Recruiting 2 6 Months 40 Jing Zhang, Wenhong Zhang 2020-06-23
A phase I clinical study of CDX-005 for the potential prevention of COVID-19 infection Coronavirus disease 19 infection CDX-005 alone Codagenix Inc Phase 1 Clinical Planned 0 2020-06-24
ALLOPRIME: Universal Anti-Viral Vaccine for Healthy Elderly Adults Coronavirus disease 19 infection AlloStim vaccine (Allo-priming, COVID-19), Immunovative Therapies alone Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) Immunovative Therapies Ltd Mirror biologics, Inc US 2020-07-06 2021-12-31 ALLOPRIME, MBI-001-ALLOPRIME, NCT04441047 Phase 1/Phase 2 Clinical Not yet recruiting 1 17 Months 40 Azriel Hirschfield, MD, Kim Demonte, Thu Bui, MHA 2020-06-29
AfriCoVER: Characterising Transmission of SARS-CoV-2 in a Peri-urban Population in Mozambique Coronavirus disease 19 infection Healthy volunteers accepted Institute of Tropical Medicine, Belgium European and Developing Countries Clinical Trials Partnership, Institut de Recherche pour le Developpement (IRD), National Institute of Health, Mozambique, Universitair Medisch Centrum Utrecht Mozambique, Belgium 2020-07-15 2021-07-14 AFRICOVER, AfriCoVER, NCT04442165 Phase Not Applicable Not yet recruiting 2 12 Months 15393 Marc-Alain Widdowson, Dr, Natacha Herssens, MSc, Yven Van Herrewege 2020-06-25
The Impact of Information Sources on Mental Health During the COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oslo Modum Bad Norway 2020-06-22 2020-07-13 NCT04442360, REK125510-13 Phase Not Applicable Not yet recruiting 3 4000 Asle Hoffart, PhD, Ole Myklebust Amundsen, Cand.Psychol Student, Omid V. Ebrahimi, Double PhD Candidate, Omid V. Ebrahimi, PhD, Sverre Urnes Johnson, PhD 2020-06-24
A phase IIa, proof-of-concept study of FSD-201 for the treatment of COVID-19 infection Coronavirus disease 19 infection palmidrol + morphine (ultramicronized, severe chronic pain), FSD Pharma alone Cannabinoid CB2 receptor modulator, Opioid receptor mu agonist FSD Pharma Inc Phase 2a Clinical Planned 0 2020-06-23
Efficacy and Safety of Nitazoxanide 600 mg to Treat Mild Ambulatory COVID-19 Patients Coronavirus disease 19 infection, Viral respiratory tract infection Standard care alone, nitazoxanide (Viranitta) alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azidus Brasil Farmoquimica SA Brazil 2020-07-31 2020-09-30 NCT04441398, NITFQM0720OR Phase 2/Phase 3 Clinical Not yet recruiting 1 2 Months 300 Edimilson Migowski, MD, Luciana Ferrara, Thiago Wendel, MD 2020-06-24
FOUND: Ancillary Study to Smile Protocol NCT03654105 Coronavirus disease 19 infection, Viral pneumonia Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Fondazione IRCCS Istituto Nazionale Tumori Universita degli Studi di Milano, Universita' Degli Studi Di Parma, University of Milano-Bicocca Italy 2019-07-23 2021-07-31 FOUND, INT 49/20, NCT04441814 Phase Not Applicable Recruiting 3 24 Months 960 Ugo Pastorino, MD 2020-06-24
Parental Stress After the Covid-19 Pandemic Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oslo Modum Bad Norway 2020-06-22 2020-07-13 NCT04442308, REK125510 (6) Phase Not Applicable Not yet recruiting 4 1440 Asle Hoffart, PhD, Miriam S Johnson, PhD, Nora Paulsen Skjerdingstad, Omid Ebrahimi, Sverre Urnes Johnson, Sverre Urnes Johnson, PhD 2020-06-25
ILIAD-7-US-I: InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic Patients With COVID-19 Infection Coronavirus disease 19 infection, Hypoxia, Lymphocytopenia, Respiratory failure CYT-107 alone IL-7 receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Revimmune Inc Amarex Clinical Research, Washington University in St Louis US 2020-06-30 2020-12-31 ILIAD-7 COVID US INFECTIOUS, ILIAD-7-US-I, NCT04442178 Phase 2 Clinical Not yet recruiting 1 6 Months 48 Frederique Berbille, MHSc, Michel Morre, DVM, Richard Hotchkiss, MD PhD 2020-06-24
PRIORITY: Prognostication of Oxygen Requirement in Non-severe SARS-CoV-2 (COVID-19) Respiratory Infection Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medecins Sans Frontieres International Centre For Diarrhoeal Disease Research, Bangladesh, The Mahidol Oxford Tropical Medicine Research Unit Bangladesh 2020-08-01 2021-03-01 0000, MSF0001, NCT04441372, PRIORITY Phase Not Applicable Not yet recruiting 1 7 Months 850 Arjun Chandna, MD, Mikhael Yosia, MD, Mohammad Shomik, MD, Sakib Burza, PhD 2020-06-26
FamilyPEDCOVID: Study of Seroprevalence of Anti-SARS-CoV2 Among Children of Hospital Workers in AP-HP Coronavirus disease 19 infection serology test alone Healthy volunteers accepted Assistance Publique Hopitaux de Paris France 2020-06-30 2020-09-30 2020-A01480-39, APHP200627, FamilyPEDCOVID, NCT04442087 Phase Not Applicable Not yet recruiting 1 3 Months 400 Flore ROZENBERG, MD, PhD, Jean-Marc TRELUYER, MD, PhD, Jean-Marc Treluyer, MD, PhD, Michaela SEMERARO, MD, Solen KERNEIS, MD, Valérie JOLAINE, Master 2020-06-25
Predictors and Mechanisms of Depression and Anxiety During the COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oslo Modum Bad Norway 2020-06-22 2020-07-13 NCT04442204, REK125510-10 Phase Not Applicable Not yet recruiting 2 4000 Asle Hoffart, PhD, Omid Ebrahimi, Double PhD Candidate, Omid V. Ebrahimi, Double PhD Candidate, Sverre Urnes Johnson, PhD 2020-06-25
PsyCOVID: Ethical and Psychological Support for Health Care Professions in Intensive Care Units in the COVID-19 Pandemic Context: Adequacy With Needs and Psychological Impact Crisis and Post-crisis Coronavirus disease 19 infection, Psychiatric disorder Limesurvey platform alone, psychological interview alone, sociological interview alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire Dijon France 2020-04-21 2020-11-30 NCT04441476, PsyCOVID, QUENOT SERI 2020 Phase Not Applicable No longer recruiting 1 7 Months 3000 2020-06-25
PTSD Symptoms Among Health Workers and Public Service Providers After the COVID-19 Outbreak: A 3 Month, Follow-up Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oslo Modum Bad Norway 2020-06-22 2020-07-13 NCT04442243, REK125510 (4) Phase Not Applicable Not yet recruiting 2 889 Asle Hoffart, PhD, Omid Ebrahimi, Omid Ebrahimi, Mr, Sverre Urnes Johnson, Sverre Urnes Johnson, PhD 2020-06-25
MARACOVID: Study to Evaluate the Efficacy and Safety of Maraviroc in SARS-CoV-2 Infection (COVID-19) Coronavirus disease 19 infection, Respiratory distress syndrome Standard care therapy alone, maraviroc alone CCR5 chemokine antagonist, CD4 agonist, HIV-1 gp120 protein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Universitario Infanta Leonor GlaxoSmithKline plc, Hospital Clinic of Barcelona Spain 2020-06-26 2020-12-20 2020-002011-21, MARACOVID, MARACOVID, NCT04441385 Phase 2 Clinical Not yet recruiting 2 5 Months 200 Berta Torres, PhD, MD, Felipe García, PhD, MD, Guillermo Cuevas, MD, Jesus Troya, MD, Montserrat Laguno, PhD, MD, Pablo Ryan, MD, Rosa María Muñoz, Victor Domínguez, MD, Víctor Domínguez, MD, Álex Soriano, PhD, MD 2020-06-29
COVID_OMICS: Identification of Predictors for the Evolution of COVID-19 Related Pneumonia by Transcriptomic and Seroproteomic Cardiovascular injury, Coronavirus disease 19 infection, Interstitial lung disease, Viral pneumonia blood sampling alone, chest x-ray alone, computed tomography alone, echocardiography alone, genome analysis alone, seroproteomic analysis alone, transcriptional analysis alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) IRCCS Policlinico San Donato Italy 2020-03-30 2020-12-31 COVID19_OMICS, COVID_OMICS, NCT04441502 Phase Not Applicable Recruiting 1 9 Months 240 Ekaterina Baryshnikova, PhD, Fabio Martelli, PhD, Marco Ranucci, MD, Marco Ranucci, MD FESC, Massimiliano M Corsi Romanelli, MD PhD, Rosanna Cardani, PhD 2020-06-25
NasoVAX in Patients With Early Coronavirus Infectious Disease 2019 (COVID-19) Coronavirus disease 19 infection NasoVAX alone Hemagglutinin modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Altimmune Inc 2020-06-30 2020-12-31 ALT-601-201, NCT04442230 Phase 2 Clinical Not yet recruiting 0 6 Months 96 Christine Orlando, Staci Steele 2020-06-25
Evaluation of a COVID-19 antibody test: What is the performance of the Panbio COVID-19 IgG/IgM rapid test device in fingerstick blood, venous whole blood, serum and plasma in adult participants? Coronavirus disease 19 infection Panbio alone Abbott Laboratories Ltd UK 2020-04-06 2020-07-03 CLDG-0503, IRAS 283040, ISRCTN60400862 Phase Not Applicable No longer recruiting 2 2 Months Prof T.Kennedy 2020-06-29
Parental Burnout During the COVID-19 Pandemic: Risk Factors and Predictors Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oslo Modum Bad Norway 2020-06-22 2020-07-13 NCT04442386, REK125510-15 Phase Not Applicable Not yet recruiting 2 1500 Asle Hoffart, PhD, Miriam Sinkerud Johnson, PhD, Nora Paulsen Skjerdingstad, Cand.psychol. stud, Omid V. Ebrahimi, Double PhD Candidate, Sverre Urnes Johnson, PhD 2020-06-24
DIAMONDS: DIAMONDS-SEARCH study: Designing new tests that can diagnose the causes of fever, including COVID-19 Coronavirus disease 19 infection Personalised Molecular Signature Diagnosis alone Imperial College London Netherlands, Germany, Greece, Switzerland, Latvia, France, Austria, Gambia, Taiwan, UK, Spain, Nepal, Slovenia, Italy 2020-01-01 2025-05-30 20SM5903, IRAS 278651, CPMS 45537, DIAMONDS, ISRCTN12394803 Phase Not Applicable Recruiting 36 64 Months 5000 Dr Federico Martinón-Torres, Prof Levin 2020-06-24
COV-IMMUNO: Immunization With IMM-101 Versus Observation for Prevention of Respiratory and Severe COVID-19 Related Infections in Cancer Patients at Increased Risk of Exposure Cancer, Coronavirus disease 19 infection, Lymphoma, Multiple myeloma, Respiratory tract infection, Solid tumor IMM-101 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Canadian Cancer Trials Group ATGen Canada Inc, BioCanRx, Canadian Cancer Society, Canadian Centre for Applied Research in Cancer Control, Immodulon Therapeutics Ltd 2020-07-01 2021-03-31 COV-IMMUNO, IC8, NCT04442048 Phase 3 Clinical Not yet recruiting 0 9 Months 1500 Auer, Chris O'Callaghan, Rebecca A Auer 2020-06-24
Difficulties in Emotion-regulation and Interpersonal Problems During and After the COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection, Depression Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oslo Modum Bad Norway 2020-06-22 2020-07-13 NCT04442282, REK125510 (5) Phase Not Applicable Not yet recruiting 2 5041 Asle Hoffart, PhD, Jon Monsen, PhD, Ole Andrè Solbakken, PhD, Omid Ebrahimi, Mr, Sverre Urnes Johnson, PhD 2020-06-24
A trial to evaluate ciclesonide for the treatment of patients with covid-19 Coronavirus disease 19 infection ciclesonide (nasal/aerosol formulation), Covis/AstraZeneca alone University at Buffalo US 2020-06-18 Phase 3 Clinical Recruiting 1 400 2020-06-23
CoVid3S: Caregiver Serological Monitoring Extended Secondarily to Patients With the SARS-CoV-2 Coronavirus Coronavirus disease 19 infection Healthy volunteers accepted Hospices Civils De Lyon France 2020-07-31 2022-01-31 69HCL20_0395, CoVid3S, NCT04441710 Phase Not Applicable Not yet recruiting 4 18 Months 2500 Antonin BAL, MD, Bruno POZZETTO, MD, François GUEYFFIER, MD, Julien LUPO, MD, Marine ALEXANDRE, Pascal FASCIA, MD 2020-06-24
NOXCOVID-1: A Phase I dose-escalation and dose-expansion study to evaluate the safety and proof-of- principle endpoints (biomarker and clinical responses)in SARS-CoV-2 infected patients Coronavirus disease 19 infection, Respiratory insufficiency, Septic shock idronoxil (suppository, late-stage prostate cancer/soft tissue sarcoma/cancers/COVID-19-associated diseases), Noxopharm alone CASP8-FADD-like regulator inhibitor, Ecto NOX disulfide thiol exchanger 2 inhibitor, Sphingosine kinase inhibitor, Sphingosine-1-phosphate receptor-1 antagonist, Stimulator of interferon genes protein stimulator, Topoisomerase inhibitor, X-linked inhibitor of apoptosis protein inhibitor Noxopharm Ltd Moldova, Republic of, Ukraine NOXCOVID-1 Phase 1 Clinical Planned 2 40 2020-06-29
HCW: Cross-sectional Study on Prevalence of COVID-19 Positive Cases Among The Healthcare Workers Via COVID-19 Screening Program In Sabah Women And Children Hospital Coronavirus disease 19 infection COVID-19 Screening Program alone Healthy volunteers accepted Sabah Women and Children's Hospital Malaysia 2020-07-01 2020-10-31 55335, HCW, NMRR-20-1199-55335 Phase Not Applicable Status not specified 1 4 Months Dr Audrey Chong Shuk Lan, Dr WONG WEI KONG 2020-06-25
Drug Utilization Review: Treatment of COVID-19 Coronavirus disease 19 infection atazanavir sulfate + ritonavir (HIV infection), Mylan Laboratories alone, chloroquine alone, favipiravir alone, hydroxychloroquine alone, interferon beta 1b alone, lopinavir + ritonavir alone, ribavirin alone, tocilizumab alone HIV protease inhibitor, RNA polymerase inhibitor Hospital Sungai Buloh Malaysia 2020-06-22 2020-08-31 55117, NMRR-20-1192-55117 Phase Not Applicable Status not specified 1 2 Months Ms Hannah binti Md Mahir 2020-06-25
COVID-19 in kidney transplant recipient Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Seth GS Medical College India 2020-06-26 CTRI/2020/06/026000 Phase Not Applicable Not yet recruiting 1 75 Dr Divya Bajpai, Dr Tukaram Jamale 2020-06-24
Clinical trial of ShatPlus as an immunomodulator in adult Covid 19 positive patients Coronavirus disease 19 infection ShatPlus alone, Standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) BVG Life Sciences Ltd India 2020-06-27 CTRI/2020/06/025999, MHC/CT/20-21/003 Phase 2 Clinical Not yet recruiting 1 60 Dr Pawan Kumar Singh, Dr Tushar V Patil 2020-06-24
Efficacy of An Ayurvedic Preparation Raj Nirwan Bati (RNB) on symptomatic COVID-19 Patients Coronavirus disease 19 infection Raj Nirwan Bati alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Uttar Pradesh University of Medical Sciences India 2020-06-30 CTRI/2020/06/025998 Phase 3 Clinical Not yet recruiting 1 60 Dr Naresh Pal Singh, Dr Raj Kumar 2020-06-24
A Clinical Evaluation of the combination Giloy Gomutra Capsules, Asthi Churna and Kamdhenu Asava in the Management of the Pandemic- Covid-19 Coronavirus disease 19 infection Variable regimens including Asthi Churna , Giloy gaumutra , Kamdhenu Asava Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) GMERS Medical College and Hospital India CTRI/2020/06/025996 Phase Not Applicable Not yet recruiting 1 200 Dr Dineshchandra Pandya, Urvi Pandya 2020-06-24
Miscarriage COVID Coronavirus disease 19 infection Sarawak General Hospital Malaysia 2020-06-14 2020-06-30 55402, NMRR-20-1153-55402 Phase Not Applicable Completed 1 Dr. Wong Tze Cheng 2020-06-24
A phase I/II trial of plasma-derived anti-SARS-CoV-2 IgG (COVID-19), Kedrion Biopharma/Kamada for the treatment of Coronavirus disease 19 infection Coronavirus disease 19 infection plasma-derived anti-SARS-CoV-2 IgG (COVID-19), Kedrion Biopharma/Kamada alone Kamada Ltd Israel 2020-09-30 Phase 1/Phase 2 Clinical Planned 1 2020-06-23
Brain Health in the Time of COVID-19 Cognitive disorder, Coronavirus disease 19 infection cognitive screening tool alone, tablet-based games alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Miro Health Johns Hopkins University, University of Pittsburgh US 2020-06-16 2020-12-31 MIRO_001_2020, NCT04438967 Phase Not Applicable Recruiting 1 6 Months 10000 Natasha Belfor, PhD, Shenly Glenn, BS 2020-06-26
Evaluation of the effect of nano micelles containing curcumin (Sina Ccurcumin) as a therapeutic supplement in patients with COVID-19 Coronavirus disease 19 infection SinaCurcumin alone, routine treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bandare-abbas University of Medical Sciences Iran 2020-07-05 IR.HUMS.REC.1399.174, IRCT20200611047735N1 Phase Not Applicable Not yet recruiting 1 40 Amin Reza Nikpoo, Amin Reza Nikpoor, Teymour agha mollaie 2020-06-24
Study of Use of Ayurveda Intervention (Ayush-64) in COVID 19 Coronavirus disease 19 infection AYUSH 64 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) National Institute of Ayurveda Jaipur Rajasthan India 2020-07-01 CTRI/2020/06/026002 Phase 2 Clinical Not yet recruiting 1 60 Dr Jaykaran Charan, Dr Pankaj Bhardwaj, Prof Pawan kumar Godatwar 2020-06-22
RIVET-COV: Ivermectin in COVID Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-06-25 CTRI/2020/06/026001, RIVET-COV Phase 2/Phase 3 Clinical Not yet recruiting 1 60 Anant Mohan 2020-06-22
CANCOV SURVEY: CANCER care in COVID-19 ERA – A survey proposed to study the treatment preference and perspectives of patients with blood cancer in a highly specialized cancer care hospital in India during COVID-19 ERA Acute leukemia, Chronic leukemia, Coronavirus disease 19 infection, Hematological neoplasm, Lymphoma, Multiple myeloma cancer-directed chemo/immune or targeted therapy alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Hospital India 2020-06-15 CANCOV SURVEY, CTRI/2020/06/026039 Phase Not Applicable Not yet recruiting 1 213 Dr Avinash Bonda 2020-06-22
Pooled testing for COVID Coronavirus disease 19 infection SARS CoV-2 RT-PCR testing alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Centre for Biological Sciences India 2020-06-22 CTRI/2020/06/026005 Phase Not Applicable Not yet recruiting 3 321 Dasaradhi Palakodeti, Manoj Gopalkrishnan, Omshree Shetty, Priya Ranganathan, R Parthiban, Uma Ramakrishnan 2020-06-24
A follow-up study of novel coronavirus pneumonia (COVID-19) patients in Wanzhou District, Chongqing Coronavirus disease 19 infection, Viral pneumonia Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The second Clinical Hospital of Chongqing Medical University China 2020-06-01 2020-11-01 ChiCTR2000033980 Phase Not Applicable Not yet recruiting 1 5 Months 67 Depeng Jiang, Lingfang Xu 2020-06-24
A larger phase II clinical trial of SARS-CoV-2 mRNA vaccine (COVID-19), CureVac in the prevention of coronavirus infection Coronavirus disease 19 infection SARS-CoV-2 mRNA vaccine (COVID-19), CureVac alone COVID19 Spike glycoprotein modulator CureVac AG 2020-10-31 Phase 2 Clinical Planned 0 2020-06-23
The Impact of a Societal Lockdown on Those With Spinal Cord and Brain Injuries Brain injury, Coronavirus disease 19 infection, Spinal cord injury, Stroke Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lawson Health Research Institute Canada 2020-06-30 2020-12-31 115999, NCT04426071 Phase Not Applicable Not yet recruiting 1 6 Months 142 Eldon Loh, MD, Swati Mehta, PhD 2020-06-22
Efficacy of Blood Purification Techniques on COVID-19 Pneumonia Coronavirus disease 19 infection, Respiratory distress syndrome Continuous Renal Replacement Therapy alone, Hemoperfusion alone, anti-complement filter with crrt system alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shahid Beheshti University Iran 2020-03-20 2020-05-21 IR.SBMU.NRITLD.REC.1399.011, IRCT20150107020592N29 Phase 3 Clinical Completed 1 2 Months 12 Seyed Mohammad Reza Hashemian, Seyed Mohammad reza Hashemian, Seyyed Mohammadreza Hashemian 2020-06-29
A clinical study of TNX-1800 for the potential prevention of COVID-19 infection Coronavirus disease 19 infection TNX-1800 alone COVID19 Spike glycoprotein modulator Southern Research Institute, Tonix Pharmaceuticals Holding Corp Phase Not Applicable Planned 0 2020-06-22
A new feasibility, phase I study to test Hemopurifier in patients with SARS-CoV-2/COVID-19 Acute lung injury, Coronavirus disease 19 infection Hemopurifier alone Aethlon Medical Inc US Phase 1 Clinical Not yet recruiting 1 40 2020-06-22
COVER: Covidivermectin: Ivermectin for Treatment of Covid-19 Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ospedale Sacro Cuore don Calabria Istituto di Ricerche Farmacologiche Mario Negri Italy, Spain 2020-06-30 2020-10-31 COVER, COVER_1, NCT04438850 Phase 2 Clinical Not yet recruiting 7 4 Months 102 Dora Buonfrate, Giovanni Pedrotti, Guido Celleri, José Muñoz, Luciano Attard, Spinello Antinori, Zeno Bisoffi, Zeno Bisoffi, PhD 2020-06-23
A study on the prevalence of infection in dental institutions by measuring the antibody titer to COVID-19 of the staff members of Kanagawa Dental College Medical Center Coronavirus disease 19 infection COVID-19 PCR test alone, ELISA alone, immunochromatography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kanagawa Dental University Japan 2020-06-22 UMIN000040733 Phase Not Applicable Not yet recruiting 1 300 Keiichi Tsukinoki, Keisuke Handa 2020-06-23
A clinical trial to evaluate the safety and efficacy of ARDS-003 in the prevention of Acute Respiratory Distress Syndrome (ARDS) development in hospitalized patients with COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome PPP-003 (intravenous), Tetra Bio-Pharma alone Cannabinoid CB2 receptor agonist Tetra Bio-Pharma Inc Canada Phase Not Applicable Planned 1 2020-06-25
A clinical trial to evaluate the safety and efficacy of ARDS-003 in the prevention of Acute Respiratory Distress Syndrome (ARDS) development in hospitalized patients with COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome PPP-003 (intravenous), Tetra Bio-Pharma alone Cannabinoid CB2 receptor agonist Tetra Bio-Pharma Inc US Phase Not Applicable Planned 1 2020-06-25
COBRA: Efficacy and Safety of VPM-1002 in Reducing SARS-CoV-2 (COVID-19) Infection Rate and Severity Coronavirus disease 19 infection VPM-1002 alone Listeriolysin stimulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University Health Network Max Planck Institute for Infection Biology, Serum Institute of India Ltd, Verity Pharmaceuticals Inc Canada 2020-06-14 2021-06-01 20-5413, COBRA, NCT04439045 Phase 3 Clinical Not yet recruiting 1 11 Months 3626 Alexandre R Zlotta, MD PhD, Cynthia Kuk, MSc, Miran Kenk, PhD 2020-06-23
FITE19: A Study to Evaluate Efficacy and Safety of PTC-299 in Hospitalized Participants With Coronavirus (COVID-19) Coronavirus disease 19 infection PTC-299 alone, Standard of care alone Dihydroorotate dehydrogenase inhibitor, IL-6 receptor antagonist, VEGF receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) PTC Therapeutics Inc Australia, Brazil, Europe, US, Spain 2020-06-30 2021-01-30 2020-001872-13, FITE19, NCT04439071, PTC299-VIR-015-COV19 Phase 2/Phase 3 Clinical Not yet recruiting 7 7 Months 380 Patient Advocacy, Quintus Ngumah, OD, PhD 2020-06-24
A clinical trial to evaluate the safety of ARDS-003 in healthy subjects Coronavirus disease 19 infection, Inflammatory disease, Respiratory distress syndrome PPP-003 (intravenous), Tetra Bio-Pharma alone Cannabinoid CB2 receptor agonist Healthy volunteers accepted Tetra Bio-Pharma Inc Phase Not Applicable Planned 0 2020-06-25
Isolated During COVID-19: Effects of COVID-19's Social Restrictions on Loneliness and Psychosocial Symptomatology Alcoholism, Anxiety disorder, Coronavirus disease 19 infection, Depression, Drug dependence socially restriction alone Healthy volunteers accepted, Young Adults (18-44 yrs) University of Miami US 2020-04-22 2020-05-11 20200446, NCT04440098 Phase Not Applicable Completed 1 1008 Viviana E Horigian, MD 2020-06-23
COLD: COVID-19 in Patients With Chronic Liver Diseases Alcoholic liver disease, Autoimmune hepatitis, Coronavirus disease 19 infection, Hepatitis B virus infection, Hepatitis C virus infection, Hepatocellular carcinoma, Liver cirrhosis, Non alcoholic fatty liver disease, Primary biliary cholangitis, Primary sclerosing cholangitis Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stanford University US 2020-03-06 2021-06-30 55819, COLD, NCT04439084 Phase Not Applicable Recruiting 21 15 Months 1000 Renumathy Dhanasekaran, MD 2020-06-23
A multicenter clinical study: transmission of COVID-19 and impact on health and developmental outcomes among newborns of mothers with confirmed/suspected COVID-19 Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Hubei Maternal and Child Health Hospital The Hong Kong Committee for UNICEF China 2020-02-10 2020-12-31 ChiCTR2000033960 Phase 0 Clinical Recruiting 10 10 Months 90 Shiwen Xia 2020-06-23
Investigation of Fatigue, Physical Activity, Sleep Quality and Anxiety Levels Anxiety disorder, Coronavirus disease 19 infection, Fatigue, Multiple sclerosis Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ankara Yıldırım Beyazıt University Turkey 2020-05-05 2020-06-18 2020, NCT04438954 Phase Not Applicable Completed 1 1 Month 30 2020-06-23
Psychological Preparedness towards Novel Coronavirus Precautionary Measures – an online survey Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chinese University of Hong Kong China 2020-06-16 2021-06-15 ChiCTR2000033936 Phase Not Applicable Recruiting 1 12 Months 1000 Allen Ting Chun LEE, Linda Chiu Wa LAM 2020-06-23
Virtual Assistant for COVID-19 PPE Coronavirus disease 19 infection Amazon Alexa alone, Human Coach alone, Virtual Assistant alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University Health Network 2020-06-30 2021-05-01 20-5399, NCT04435275 Phase Not Applicable Not yet recruiting 0 10 Months 50 Rongyu ( Cindy) Jin 2020-06-24
A medical records based study for the influence of novel coronavirus pneumonia (COVID-19) on the symptoms of patients with achalasia Achalasia, Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) General Hospital of Tianjin Medical University National Natural Science Foundation of China China 2020-06-16 2020-06-23 ChiCTR2000033919 Phase Not Applicable Recruiting 1 286 LingYun Zhang, Wei Zhao 2020-06-30
CP IN COVID19: Use of Convalescent Plasma for Treatment of Patients With COVID-19 Infection Coronavirus disease 19 infection, Respiratory failure convalescent plasma alone, standard of care alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Cairo University Egypt 2020-06-01 2021-12-31 CP IN COVID19, N39-2020, NCT04438694 Phase 1/Phase 2 Clinical Recruiting 1 19 Months 60 Akram AbdelBarry, MD PhD, Ashraf ElFiky, MD PhD, Azza AboulEnin, MD PhD, Heba Sharaf, Md PhD, Mostafa ElShazly, MD PhD, Nermeen El Desouky, Nermeen ElDesouky, MD PhD, Omar Fahmy, MD PhD, Yasser Nassar, MD PhD 2020-06-23
OBVIONCO: Prospective, Cohort Study to Describe the Clinical Characteristics of COVID-19, the Acquired Immune Response and the Biological and Clinical Parameters of Patients Followed in Oncology by the Saint-Joseph Hospital Group for a Period of 6 Months During the COVID-19 Pandemic Coronavirus disease 19 infection Obvio-19 mobile app alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Groupe Hospitalier Paris Saint-Joseph ObvioHealth France 2020-06-30 2021-12-31 NCT04437719, OBVIONCO, OBVIONCO Phase Not Applicable Not yet recruiting 1 18 Months 100 Eric Raymond, MD, Helene Beaussier, PharmD, pHD 2020-06-23
IMMUNOVID: Evaluation of Immune Response in COVID-19 Patients Coronavirus disease 19 infection antibiotic prophylaxis alone, anticoagulant treatment alone, hydroxychloroquine alone, lopinavir + ritonavir alone, off-label therapy alone, hydroxychloroquine plus lopinavir + ritonavir HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Ospedaliera Universitaria Integrata Di Verona Italy 2020-03-26 2020-11-26 IMMUNOVID, IMMUNOVID 2590CESC, NCT04438629 Phase Not Applicable Recruiting 2 8 Months 80 STEFANO UGEL, VINCENZO BRONTE, MD 2020-06-23
Hydroxychloroquine Post-Exposure Prophylaxis for Coronavirus Disease (COVID-19) Among Health-Care Workers Coronavirus disease 19 infection hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rambam Health Care Campus Israel 2020-06-30 2022-06-30 0193-20-RMB CTIL, NCT04438837 Phase 2 Clinical Not yet recruiting 1 24 Months 582 Mical Paul, MD, Nesrin Ghanem-Zoubi, Nesrin Ghanem-Zoubi MD, Nesrin Ghanem-Zoubi, MD 2020-06-25
COVID-PRONE: Contribution of a Prone Team in Intensive Care During the Covid-19 Epidemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg France 2020-03-25 2020-06-20 7911, COVID-PRONE, NCT04438941 Phase Not Applicable Recruiting 1 2 Months 100 Anne-Florence ROUBY, MD, Bob HEGER, MD, Nabil CHAKFE, MD, PhD, Olivier COLLANGE, MD, PhD, Paul-Michel MERTES, MD, PhD, Saïd CHAYER, PhD, HDR 2020-06-24
Daily Home Spirometry for Early Detection of Pulmonary Complications in Patients With COVID19 Coronavirus disease 19 infection, Respiratory disease Portable hand-held spirometer alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sheba Medical Center Israel 2020-09-01 2021-09-01 NCT04438863, SHEBA-20-7022-SMC-LL-CTIL Phase Not Applicable Not yet recruiting 1 12 Months 90 Dr. Liran Levy, Transplant pulmonologist 2020-06-23
COVICARE: The COVID-19 Disease and Cardiac Events Study Coronavirus disease 19 infection, Heart injury echocardiography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NHS Lanarkshire UK 2020-05-29 2020-11-30 COVI-RW-2020, COVICARE, NCT04438993 Phase Not Applicable Recruiting 1 6 Months 100 Robin A Weir, MD, Robin AP Weir, MD 2020-06-23
To study effect of Ivermectin drug in patients infected with SARS-CoV-2 virus Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Symbiosis International University India 2020-06-18 CTRI/2020/06/025960 Phase 2 Clinical Not yet recruiting 1 100 Dr Meenakshi Bhakare, Dr Rajkumar Nikalje, Dr Vijay Natarajan 2020-06-23
A clinical trial of BD-368-2 for SARS-CoV-2 infection Coronavirus disease 19 infection BD-368-2 alone COVID19 Spike glycoprotein modulator Peking University Beijing Advanced Medical Technologies Inc Phase Not Applicable Planned 0 2020-06-23
Clinical Study to Study Safety and Efficacy of herbal formulation - Aayudh Advance Coronavirus disease 19 infection Aayudh Advance alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shukla Ashar Impex Pvt. Ltd., Rajkot India 2020-06-22 ARL/CSP/2020/003-00, CTRI/2020/06/025977 Phase 2 Clinical Recruiting 1 120 Dr Bhavdeep Ganatra, Dr Manish Rachchh, Dr Parul Bhatt 2020-06-23
Ibrutinib for the Treatment of COVID-19 in Patients Requiring Hospitalization Aplastic anemia, Coronavirus disease 19 infection, Hematological neoplasm, Lymphocytosis, Myelodysplastic syndrome, Paraproteinemia, Solid tumor ibrutinib alone Btk tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ohio State University Comprehensive Cancer Center National Cancer Institute US 2020-06-15 2022-12-31 NCI-2020-03341, NCT04439006, OSU-20135, P30CA016058 Phase 2 Clinical Not yet recruiting 1 30 Months 72 Jennifer A Woyach, MD, Jennifer A. Woyach, MD, Kaitlyn Dvorak, Ohio State Comprehensive Cancer Center 2020-06-23
A Clinical study of CWP-291 in treatment of COVID-19 Coronavirus disease 19 infection CWP-291 alone Beta-catenin inhibitor JW Pharmaceutical Corp US, South Korea Phase Not Applicable Completed 2 2020-06-22
Study of the Efficacy and Safety of STI-5656 (Abivertinib Maleate) With SOC Versus SOC in Subjects With COVID-19 (SOC) Coronavirus disease 19 infection, Viral pneumonia abivertinib alone, standard of care alone Btk tyrosine kinase inhibitor, EGFR gene inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sorrento Therapeutics Inc 2020-08-31 2021-03-31 NCT04440007, STI-5656-2001 Phase 2 Clinical Not yet recruiting 0 7 Months 80 Andreas G Niethammer, MD PhD, Ying Yan, MD MS 2020-06-26
An international, randomized, controlled trial to evaluate non-licensed COVID-19 treatments in addition to standard of care among hospitalized patients Coronavirus disease 19 infection hydroxychloroquine alone, lopinavir + ritonavir alone, remdesivir alone, standard care alone, interferon beta-1a plus lopinavir + ritonavir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, HIV protease inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Peruana Cayetano Heredia Ministry Of Health, Lima Peru Switzerland, Peru, Argentina, Iran, India, Norway, Bahrain, Thailand, South Africa, Spain 2020-04-03 PER-010-20 Phase 4 Clinical Recruiting 20 50000 ALEJANDRO PEÑA VILLALOBOS, ALONSO RICARDO SOTO TARAZONA, Alejandro DALY TURCKE, Anabel Viton Espino, Andres Martín Alcantara Díaz, Anna Larson Williams, CLAUDIA LIZETTE BANDA FLORES, Carla Cornejo Valdivia, Carlos Velapatiño Flores, EDISON DANTE MEREGILDO RODRIGUEZ, EPIFANIO SANCHEZ GARAVITO, FRANCO LEON JIMENEZ, Fernando Mejia Cordero, GERMAN JAVIER MALAGA RODRÌGUEZ, GONZALO GIANELLA MALCA, Guillermo Carlos Contreras Nogales, HUGO ARBAÑIL HUAMAN, Hernán Sandoval Manrique, JESUS CHACALTANA HUARCAYA, JORGE MANUEL DE LOS RÍOS SENMACHE, JORGE WATANBE NOJI, Jenny Perez Cervantes, Jesus Canales Vargas, Jesus Juarez Eyzaguirre, Jesus Valverde Huaman, Jose Eduardo Gotuzzo Herencia, Juan Pablo Majluf Brahim, Julio Antonio Silva Ramos, Julio Bolaños Vargas, Kory Marcela Argumedo Estay, Kory Rojas Murrugarra, LUIS ENRIQUE HERCILLA VASQUEZ, LUIS RICARDO ILLESCAS MUCHA, Luis Castillo sin, MARIA ANGELICA PAREDES MORENO, MARIO PATRICIO CORNEJO GIRALDO, MARTIN MONTES DELGADO, MARTIN OYANGUREN MIRANDA, MIGUEL HUEDA ZAVALETA, Manuel Eduardo Giron Silva, Martin Montes Delgado, Miguel Villegas Chiroque q, Oscar Martín Torres Ruiz, Patricia García Funegra, Paula Ponce de León Lovatón, Pedro Alberto Sullon Zavaleta, Raul Junior Gonzalez Navarro, Ricardo Manuel Sanchez Sevillano, Rocío Jiménez Rodriguez, Rosa Lopez Martinez, Walter Hidalgo Caceres 2020-06-23
An Open Study of the Safety, Tolerability and Immunogenicity of 'Gam-COVID-Vac Lyo' Vaccine Against COVID-19 Coronavirus disease 19 infection Gam-COVID-Vac alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Gamalei Institute of Epidemiology and Microbiology Accellena Research and Development Russian Federation 2020-06-17 2020-08-15 03-GAM-COVID-VAC LYO-2020, NCT04437875 Phase 1/Phase 2 Clinical Recruiting 1 1 Month 38 Inna Dolzhikova, PhD, Lola Morozova, Md 2020-06-25
A randomised, double-blind, placebo-controlled trial of SFX-01 for the treatment of COVID-19 infection Coronavirus disease 19 infection alpha-cyclodextrin-stabilized sulforaphane (cancer/multiple sclerosis/subarachnoid hemorrhage/autism/glioblastoma/Non alcoholic steatohepatitis/Non alcoholic fatty liver disease), Evgen Pharma alone Kelch like ECH associated protein 1 modulator, Nuclear erythroid 2-related factor 2 stimulator Evgen Pharma plc, University of Dundee LifeArc UK Phase Not Applicable Planned 1 2020-06-22
HCQ-COVID19: Post-Exposure Prophylaxis in Healthcare Workers Exposed to COVID-19 Patients Coronavirus disease 19 infection hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hamad Medical Corp Qatar 2020-07-01 2021-12-31 HCQ-COVID19, MRC-02-20-442, NCT04437693 Phase 3 Clinical Not yet recruiting 1 18 Months 500 Nasser Al Ansari, FRCPath, Rajvir Singh, Ph.D. 2020-06-25
A clinical trial of anti-SARS-CoV2 antibodies (COVID-19 infection), Yumab for the potential treatment of COVID-19 infection Coronavirus disease 19 infection anti-SARS-CoV2 antibodies (COVID-19 infection), Corat Therapeutics alone Corat Therapeutics GmbH, Yumab 2020-12-31 Phase Not Applicable Planned 0 2020-06-19
SEARCH: A large-scale study to better understand the spread and prevalence of the coronavirus in the local community, with an initial focus on evaluating healthcare workers and first responders Coronavirus disease 19 infection Rady Children's Hospital, San Diego, Scripps Research Institute, University of California San Diego US SEARCH Phase Not Applicable Status not specified 1 10000 Gene Yeo, Kristian Andersen, Lauge Farnaes, Louise Laurent, Rob Knight 2020-06-22
The Health Crisis at the Healthcare Professionals, Careers and Non-careers, a Month After the Containment Period Anxiety disorder, Coronavirus disease 19 infection, Depression Clinique Medipole Garonne 2020-06-15 2020-06-28 DECOVID, NCT04436861 Phase Not Applicable Not yet recruiting 0 200 Laurence Culine, Myaro Nodjialem 2020-06-22
A clinical trial of REGN-CoV2 for the treatment of COVID-19 patients (both those who are hospitalized and those who are not) Coronavirus disease 19 infection REGN-CoV2 alone Regeneron Pharmaceuticals Inc, University of Maryland Medical Center Phase Not Applicable Recruiting 0 2020-06-19
REACT: Rehabilitation Needs After COVID-19 Hospital Treatment Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Unita Sanitaria Locale di Reggio Emilia Italy 2020-06-30 2020-12-31 428/2020/OSS/AUSLRE, NCT04438239, REACT Phase Not Applicable Not yet recruiting 1 6 Months 100 Stefania Costi, PhD, Stefania Fugazzaro, MD 2020-06-23
Open-label, placebo-controlled, multicenter, clinical trial to assess the effect and safety of Favipiravir compared to standard care in the management of adult patients with moderate Covid-19 at risk of serious complications Coronavirus disease 19 infection favipiravir alone RNA polymerase inhibitor Hospital Regional de Alta Especialidad de Ixtapaluca Mexico C32-20 Phase 3 Clinical Status not specified 1 200 2020-06-22
Efficacy of Intravenous Infusions of Stem Cells in the Treatment of COVID-19 Patients Coronavirus disease 19 infection, Lung inflammation standard of care alone, Variable regimens including allogeneic human umbilical cord mesenchymal stem cells (iv, COVID-19), Jinnah Hospital/Johns Hopkins University Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Jinnah Hospital Johns Hopkins University Pakistan 2020-06-01 2021-06-30 JB and RSC-01, NCT04437823 Phase 2 Clinical Recruiting 1 13 Months 20 Azra Mehmood, PhD, Moazzam N Tarar, MBBS, FCPS, Mohsin Shahzad, PhD, Prof. Sheikh Riazuddin, Sheikh Riazuddin, PhD 2020-06-26
Niclosamide In Moderate COVID-19 Coronavirus disease 19 infection, Gastrointestinal disease, Viral pneumonia Standard of care therapy alone, niclosamide alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) First Wave Bio, Inc 2020-08-31 2021-02-28 FW-COV-002, NCT04436458 Phase 2 Clinical Not yet recruiting 0 6 Months 100 Tony Opipari, M.D. 2020-06-22
IBOC: Immune Biomarkers of Outcome From COVID-19 Coronavirus disease 19 infection, Immune disorder Peripheral blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Plymouth NHS Trust UK 2020-04-29 2020-10-28 20/HEP/381, IBOC, NCT04436484 Phase Not Applicable Recruiting 2 6 Months 200 Ashwin D Dhanda, MRCP PhD, Christopher Rollinson 2020-06-23
Adalimumab effect on COVID-19 Coronavirus disease 19 infection adalimumab alone TNF alpha ligand inhibitor, TNF binding agent Bagheiat-allah University of Medical Sciences Iran 2020-04-29 IR.BMSU.REC.1399.062, IRCT20171105037262N4 Phase 3 Clinical Recruiting 1 100 Hassan Nikoueinejad, Hassan Nikoueinejas, Mohammad Hossein Pourhanifeh 2020-06-22
Treatment of COVID-19 with the inhalation drug pulmozyme Coronavirus disease 19 infection, Respiratory disease dornase alfa alone Deoxyribonuclease I stimulator, Deoxyribonuclease stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Region Skane Sweden 2020-05-18 2020-001849-39, NETs-C19 Phase 2 Clinical Recruiting 1 Adam Linder 2020-06-22
Evaluating the Efficacy of Convalescent Plasma in Symptomatic Outpatients Infected With COVID-19 Coronavirus disease 19 infection convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Metro Infectious Disease Consultants US 2020-07-06 2021-07-06 MIDC-CCP, NCT04438057 Phase 2 Clinical Not yet recruiting 1 12 Months 150 Nathan Skorodin, PharmD, Nicholas Van Hise, PharmD 2020-06-23
Study evaluating the impact of BCG vaccination on the incidence and course of SARS-CoV-2 infection among health care workers in Poland during the COVID-19 pandemic Coronavirus disease 19 infection BCG vaccine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Rzeszów Medical Research Agency (Agencja Badań Medycznych) Poland 2020-06-26 2020-002111-22, BCG/COVID-19/UR/04/2020 Phase 3 Clinical Recruiting 1 National Study Coordinator 2020-06-23
A study to assess human monoclonal antibodies (Covid-19) in the treatment of patients infected with SARS-CoV-2 Coronavirus disease 19 infection human monoclonal antibodies (Covid-19), Garvan Institute/The Kirby Institute alone COVID19 Spike glycoprotein modulator The Kirby Institute (Affiliated With The University Of New South Wales) Australia Phase Not Applicable Planned 1 Professor Daniel Christ 2020-06-19
Edaravone in COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia edaravone, Zist Daru Co alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tabriz University of Medical Sciences Iran 2020-06-21 IR.TBZMED.REC.1399.128, IRCT20200317046797N6 Phase 3 Clinical Recruiting 1 30 Dr Mohammad Samiei, Mohammadreza Ardalan, Mojtaba Varshochi, Sepideh Zununi Vahed 2020-06-22
Evaluation of Vaginal Fluid for Covid-19 Positivity in Women With Positive nasopharyngeal Covid-19 Test Coronavirus disease 19 infection vginal fluid Covid-19 PCR test alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Acibadem University Turkey 2020-06-15 2020-07-30 ACIBADEM MASLAK OB&GYN, NCT04437940 Phase Not Applicable Recruiting 1 1 Month 35 Burak Celik, Eren Kaya, MD, Ozguc Takmaz, Ozguc Takmaz, Assist. Prof., Ozguc Takmaz, MD,Assist.Prof 2020-06-22
Snowball: Network-Targeted Strategies for Efficient Community SARS-CoV-2 (COVID-19) Sampling Coronavirus disease 19 infection COVID-19 testing alone, network targeted sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University US 2020-07-01 2021-06-30 NCT04437706, PRO00105430, Snowball Phase Not Applicable Not yet recruiting 1 12 Months 200 Erich Huang, MD, PhD, Margaret K Pendzich, MSPH, Margaret Pendzich, Pedro Gomez, MS 2020-06-23
COVID Screening Strategies in Homeless Shelters Coronavirus disease 19 infection daily active screening alone, self-collected nasal swabbing alone, self-collected nasopharyngeal swabbing alone, self-collected oral swabbing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Josephs Healthcare Hamilton Canada 2020-04-10 2020-06-30 2020-10864-T, NCT04438070 Phase Not Applicable Recruiting 1 2 Months 400 Marek Smieja, Marek Smieja, MD, PhD, Timothy O'Shea, MD 2020-06-23
A phase I study of PDS-0204 for the prevention of COVID-19 infection Coronavirus disease 19 infection PDS-0204 alone Farmacore Biotecnologia Limitada, PDS Biotechnology Corp Ministry of Science and Technology, Brazil Brazil Phase 1 Clinical Planned 1 2020-06-19
A Clinical study of prophylactic vaccine (Memopi, COVID-19), OSE Immunotherapeutics in COVID-19 Coronavirus disease 19 infection prophylactic vaccine (Memopi, COVID-19), OSE Immunotherapeutics alone OSE Immunotherapeutics 2020-12-31 Phase Not Applicable Planned 0 2020-06-19
A Study of Ad26-COVS1 in Adults (COVID-19) Coronavirus disease 19 infection JNJ-78436735 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Janssen Vaccines & Prevention BV US, Belgium 2020-07-13 2023-07-08 2020-001483-28, CR108828, NCT04436276, VAC31518COV1001 Phase 1/Phase 2 Clinical Not yet recruiting 12 35 Months 1045 Janssen Vaccines & Prevention B.V. Clinical Trial, Study Contact 2020-06-26
Double-blind, placebo-controlled clinical trial of the use of colchicine for the management of patients with mild and severe SARS-Cov2 infection Coronavirus disease 19 infection colchicine alone Instituto Nacional de Ciencias Medicas y Nutricion Mexico 3374 Phase 2 Clinical Status not specified 1 2020-06-19
NICCAM: A study to investigate the safety and efficacy of two approved drugs, niclosamide and camostat, administered alone and in combination and compared to placebo in COVID-19 patients Coronavirus disease 19 infection Niclosamide plus camostat mesylate Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Charite Research Organisation Bayer AG Germany 2020-06-17 2020-002233-15, NICCAM, NICCAM-001 Phase 2 Clinical Recruiting 1 72 Kristin Herzog 2020-06-22
Effect of Interferential Therapy on SARS-CoV-2. COVID-19 Coronavirus disease 19 infection SABA alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lagos State University Teaching Hospital Nigeria 2020-10-01 PACTR202006717277937 Phase 2 Clinical Not yet recruiting 1 48 Bashir Kaka, Eniola Awolola, Sonill Maharaj 2020-06-22
An Open Study of the Safety, Tolerability and Immunogenicity of the Drug 'Gam-COVID-Vac' Vaccine Against COVID-19 Coronavirus disease 19 infection Gam-COVID-Vac alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Gamalei Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation Collaborator Accellena Research and Development Russian Federation 2020-06-17 2020-08-15 02-GAM-COVID-VAC-2020, NCT04436471 Phase 1/Phase 2 Clinical Recruiting 1 1 Month 38 Inna Dolzhikova, PhD, Irina Gagarina, MD 2020-06-26
Study of vascular complications in critically ill patients with coronavirus Coronavirus disease 19 infection, Vascular disease analgesics alone, antibiotics alone, heparin alone Universidade Federal de Sao Paulo - UNIFESP Brazil 2020-04-17 3.976.579, 30667020.5.0000.5505, RBR-4qjzh7, U1111-1252-1318 Phase Not Applicable No longer recruiting 1 Luis CU Nakano, Ronald LG Flumignan 2020-06-22
COVIDAR: Arrhythmias in COVID-19 Coronavirus disease 19 infection, Heart arrhythmia SARS-CoV2 infection treatment alone, routine clinical care alone Hospital Clinic of Barcelona Academic Medical Center, University of Amsterdam, Antwerp University Hospital, European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart, European Society of Cardiology, Istituto Auxologico Italiano, St George's University Hospitals NHS Foundation Trust Italy, Spain, Belgium, UK, Netherlands 2020-06-30 2021-12-31 COVIDAR, HCB/2020/0333, NCT04437901 Phase Not Applicable Not yet recruiting 5 18 Months 10000 Alex Soriano, MD, PhD, Arthur A Wilde, MD, PhD, Elena Arbelo, MD, PhD, Elena Arbelo, MD, PhD, MSc, Elijah Behr, MD, PhD, Hein Heidbuchel, MD, PhD, Lia Crotti, MD, PhD, Marta Hernandez-Meneses, MD, Nynke Hoffman, MD, PhD 2020-06-22
Treatment of severe cases of Covid-19 with eculizumab Coronavirus disease 19 infection eculizumab alone Complement C5 factor inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital das Clinicas de Ribeirao Preto/USP Brazil 2020-05-27 30522020.0.0000.5440, 4.003.844, A10741034670, RBR-876qb5 Phase 1/Phase 2 Clinical Recruiting 1 10 Bruno Garcia Pires, Rodrigo Tocantins Calado 2020-06-22
A medical records based study for the preliminary efficacy of Tocilizumab in the treatment of the patients with novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia tocilizumab alone Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wuhan Huoshenshan Hospital, Xijing Hospital Shaanxi Provincial Science and Technology Department China 2020-02-27 2020-03-14 ChiCTR2000033705 Phase 4 Clinical No longer recruiting 1 61 Xijing Zhang 2020-06-22
COV-EAT: Dietary and Lifestyle Habits During the Pandemic of COVID-19 in Greece Coronavirus disease 19 infection Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) University of Thessaly Greece 2020-04-30 2020-05-24 COV-EAT, COV-EAT, NCT04437121 Phase Not Applicable Completed 1 397 Odysseas Androutsos, M.Med.Sci., Ph.D. 2020-06-22
A phase I study to assess the effect of human FGF-1 (long-term subcutaneous formulation, Parkinson's disease), Zhittya Genesis Medicine in patients with lung damage from COVID-19 Coronavirus disease 19 infection, Lung injury human fibroblast growth factor-1 (long-term subcutaneous formulation, Parkinson's disease/amyotrophic lateral sclerosis), Zhittya Genesis Medicine alone FGF-1 ligand Zhittya Genesis Medicine Inc Phase 1 Clinical Planned 0 2020-06-19
A case study on COVID-19 infection and treatment with hydroxychloroquine cause severe hemolysis crisis in a patient with glucose 6 phosphate dehydrogenase deficiency Coronavirus disease 19 infection, Enzyme deficiency hydroxychloroquine alone Geneva University Hospitals Phase Not Applicable Status not specified 0 1 2020-06-19
A phase I study to assess the effect of human FGF-1 (long-term subcutaneous formulation, Parkinson's disease), Zhittya Genesis Medicine in patients with COVID-19 lung damage Coronavirus disease 19 infection, Lung injury human fibroblast growth factor-1 (long-term subcutaneous formulation, Parkinson's disease/amyotrophic lateral sclerosis), Zhittya Genesis Medicine alone FGF-1 ligand Zhittya Genesis Medicine Inc Mexico Phase 1 Clinical Planned 1 2020-06-19
Postpartum Depression in the Covid-19 Pandemic and the Impact of Anesthesia Anxiety disorder, Coronavirus disease 19 infection, Postnatal depression 38 questions questionnaire alone, EPDS (Edinburgh Postnatal Depression Scale) alone, GAD-7 (General Anxiety Disorder) scale alone, PHQ-9 (Patient Health Questionnaire) Depression Scale alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) General and Maternity Hospital of Athens Elena Venizelou Alexandra Hospital, Larissa University Hospital, National and Kapodistrian University of Athens, University of Ioannina Greece 2020-06-30 2020-09-30 COVID-19 POSTPARTUM DEPRESSION, NCT04437342 Phase Not Applicable Not yet recruiting 6 3 Months 300 Chrysoula Staikou, Associate Professor, Dimitrios Valsamidis, Head of Department, Eleni Arnaoutoglou, Eleni Arnaoutoglou, Professor, Georgia Micha, PhD, Konstantinos Kotsis, Konstantinos Kotsis, Assistant Professor, Petros Tzimas, Petros Tzimas, Associate Professor 2020-06-22
The mechanism of PECAM-1 in mediating pulmonary vascular endothelial permeability through Wnt/beta-catenin signaling pathway in SARS-CoV-2-related ARDS Adult respiratory distress syndrome, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The First Affiliated Hospital of Guangzhou Medical College China 2020-07-01 2020-08-31 ChiCTR2000033699 Phase Not Applicable Not yet recruiting 1 2 Months 20 Xiaoqing Liu, Zhihui Zhang 2020-06-22
An investigator-initiated, Phase IIa, randomized, double-blind, placebo-controlled trial to assess safety and efficacy of ATI-450 in hospitalized patients with COVID-19 Coronavirus disease 19 infection ATI-450 alone Adapter molecule crk inhibitor, MAPKAPK2 inhibitor University of Kansas Medical Center Aclaris Therapeutics Inc US Phase 2a Clinical Not yet recruiting 1 36 Deepika Polineni, M.D., M.P.H, Gregory Gan, M.D., Ph.D 2020-06-19
A open-label study to target the inflammatory cascade with anakinra in moderate to severe COVID-19 pneumonia- case-series Coronavirus disease 19 infection, Pneumonia anakinra alone Type I IL-1 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Caen University Hospital Phase 2 Clinical Status not specified 0 9 2020-06-19
A clinical validation study to evaluate VaxArray Coronavirus SeroAssay for the diagnosis of COVID-19 Coronavirus disease 19 infection VaxArray coronavirus seroassay alone InDevR LLC Children's Hospital Colorado Phase Not Applicable Status not specified 0 100 2020-06-19
Effectiveness of borage based solutions in cytokine's levels in covid-19 ARDS patients Adult respiratory distress syndrome, Coronavirus disease 19 infection, Respiratory failure Borage suspension therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shahid Beheshti University of Medical Sciences, Laser Application in Medical Sciences Research Center Iran 2020-03-20 IR.SBMU.NRITLD.REC.1399.059, IRCT20150107020592N28 Phase 3 Clinical No longer recruiting 1 50 Afshin Zarghi, Seyed Mohammad Reza Hashemian, Seyyed Mohammadreza Hashemian 2020-06-24
To describe the case of a critically-ill patient with myocarditis and severe ARDS related to COVID-19 infection: A case-study Coronavirus disease 19 infection, Myocarditis, Respiratory distress syndrome AT-001 alone, fraction of inspired oxygen alone, milrinone alone, neuromuscular blockade alone, positive end-expiratory pressure alone, tocilizumab alone, Variable regimens including colchicine , methylprednisolone , prednisone PDE 3 inhibitor Male Advocate Illinois Masonic Medical Center Phase Not Applicable Status not specified 0 1 2020-06-22
USCovid: Reliability of a Pocket Sized Ultrasound Scanner in the Evaluation Covid-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia LUS (lung ultrasound scan) alone, pocket-sized ultrasound scanner (Butterfly Network Inc., Butterfly iQ) alone, ultrasound scanner (GE Healthcare, Venue GO) alone University of Siena Italy 2020-03-15 2020-06-10 NCT04433000, USCOVID, USCovid Phase Not Applicable Recruiting 1 2 Months 34 David Bennett, MD, Piersante Sestini, MD, Sestini Piersante, MD 2020-06-22
A case-series study to follow the clinical course of COVID-19 in patients with systemic lupus erythematosus (SLE) who received long-term treatment with hydroxychloroquine: a case-series Coronavirus disease 19 infection hydroxychloroquine alone, invasive mechanical ventilation alone, oxygen therapy alone, prednisone alone Sorbonne Universites Phase Not Applicable Status not specified 0 17 2020-06-19
POCUS COVID-19: Evaluation with ultrasound on the bedside in serious patients with COVID-19 Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade Federal de Sao Paulo - UNIFESP Brazil 2020-04-21 2020-07-21 3.982.657, 30815320.5.0000.5505, POCUS COVID-19, RBR-43hbks, U1111-1252-1143 Phase Not Applicable Recruiting 1 3 Months 50 Luis CU Nakano, Ronald LG Flumignan 2020-06-22
Effect of convalescent plasma in patients with severe COVI-19 Coronavirus disease 19 infection convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Estadual de Hematologia Arthur de Siqueira Cavalcanti, Instituto do Cerebro de Brasilia Brazil 2020-04-19 2020-05-31 3,980,508, 30487220.8.1001.5267 - CAAE, RBR-4vm3yy, U1111-1251-9286 Phase 2 Clinical Recruiting 1 1 Month 20 Pedro Kurtz 2020-06-22
A First-in-Human Study in Adult Subjects Hospitalized with COVID-19 to Investigate a new product called ARGX-117 Coronavirus disease 19 infection ARGX-117 alone Complement factor C2 modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) argenx BV, Belgium Belgium 2020-04-21 2020-001546-19, ARGX-117-2001 Phase 1/Phase 2 Clinical Recruiting 1 Regulatory 2020-06-22
The role of early dialysis in the evolution of patients with COVID-19 Coronavirus disease 19 infection, Renal injury hemodialysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Unidade de Pesquisa Clínica - Hospital das Clínicas da Faculdade de Medicina de Botucatu Fundacao de Amparo a Pesquisa do Estado Sao Paulo Brazil 2020-05-01 30614920.5.0000.5411, 4.004.277, RBR-3rdhgm, U1111-1251-0203 Phase Not Applicable Recruiting 1 118 Welder Zamoner 2020-06-22
Treatment of 2019-nCoV pneumonia with N-acetylcysteine Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia N-acetylcysteine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Sao Paulo Fundacao de Amparo a Pesquisa do Estado Sao Paulo Brazil 2020-04-14 3,947,348, 30420720.4.0000.0068, RBR-8969zg, U1111-1250-3564 Phase 2 Clinical Not yet recruiting 1 140 Julio Cesar Garcia de Alencar 2020-06-22
SequelaeCov: Lung Damage Caused by SARS-CoV-2 Pneumonia (COVID-19) Coronavirus disease 19 infection, Lung injury, Respiratory failure, Viral pneumonia continuous positive airway pressure therapy alone, invasive mechanical ventilation alone, non-invasive ventilation alone, oxygen support therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Milano-Bicocca Italy 2020-08-17 2021-04-30 NCT04435327, SEQUELAECOV, SequelaeCov Phase Not Applicable Recruiting 1 8 Months 300 Paola Faverio, MD 2020-06-22
VANGARD: PB-1046, a Long-acting, Sustained Release Human VIP Analog, Intended to Provide Clinical Improvement to Hospitalized COVID-19 Patients at High Risk for Rapid Clinical Deterioration and Acute Respiratory Distress Syndrome (ARDS) Coronavirus disease 19 infection, Respiratory distress syndrome PB-1046 alone VIP 2 receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) PhaseBio Pharmaceuticals Inc US 2020-06-26 2020-12-18 NCT04433546, PB1046-PT-CL-0007, VANGARD Phase 2 Clinical Not yet recruiting 1 5 Months 210 Clinical Trials 2020-06-23
A Comparative Study on Ivermectin and Hydroxychloroquine on the COVID19 Patients in Bangladesh Coronavirus disease 19 infection Variable regimens including azithromycin , doxycycline hyclate , hydroxychloroquine , ivermectin Chloride channel modulator Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ministry of Health and Family Welfare, Bangladesh Xi'an Jiaotong University Bangladesh 2020-05-02 2020-06-05 10000918, NCT04434144 Phase Not Applicable Completed 1 1 Month 116 Abu Taiub Mohammed Mohiuddin Chowdhury, MBBS, MD, Mohammad Shahbaz, MBBS, MCPS 2020-06-22
Efficacy of Hydroxychloroquine Prophylaxis for Health Care Workers at High Risk for COVID-19 Coronavirus disease 19 infection hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of New Mexico US 2020-04-14 2025-04-14 20-206, NCT04435808 Phase 1/Phase 2 Clinical Recruiting 1 60 Months 350 Hadya Khawaja, MS, Walter Dehority, Walter Dehority, MD 2020-06-22
Effectiveness of herbal capsule in COVID-19 Coronavirus disease 19 infection herbal powder capsule (Punica granatum, Rheum palmatum, Glycyrrhiza glabra and Nigella sativa) alone, standard COVID-19 treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Kerman University of Medical Sciences Iran 2020-04-20 IR.KMU.REC.1399.055, IRCT20200330046899N1 Phase 3 Clinical Recruiting 1 50 Abbas Pardakhti, Dr. Hamid Aboosaeidi, Dr. Mohammad Setayesh, Mohammad Seatyesh, Mohammad Setayesh 2020-06-22
Study of the Efficacy and Safety of Intravenous Pamrevlumab, in Hospitalized Patients With Acute COVID-19 Disease Coronavirus disease 19 infection, Viral pneumonia pamrevlumab alone, standard-of-care alone Connective tissue growth factor ligand inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) FibroGen Inc US 2020-06-20 2021-01-31 FGCL-3019-098, NCT04432298 Phase 2 Clinical Recruiting 2 7 Months 130 Gustavo Lorente 2020-06-25
A Randomized Controlled Trial Assessing the Efficacy of Lianhua Qingwen as an Adjuvant Treatment in Patients With Mild Symptoms of COVID-19 Coronavirus disease 19 infection lianhua qingwen (oral/capsule, influenza), Yiling Pharmaceutical alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nanyang Technological University Ministry of Health, Singapore Singapore 2020-07-31 2021-02-28 IRB-2020-05-029, NCT04433013 Phase 3 Clinical Not yet recruiting 1 7 Months 300 Hui Zi Chua, Yan Zhao 2020-06-22
CRITICAL: Crizanlizumab for Treating COVID-19 Vasculopathy Coronavirus disease 19 infection, Inflammatory disease, Respiratory tract infection, Thrombosis, Vascular disease crizanlizumab alone P selectin antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johns Hopkins University Brigham & Women's Hospital, Novartis AG, SOCAR Research SA US 2020-06-30 2020-10-31 CRITICAL, IRB00249874, NCT04435184 Phase 2 Clinical Not yet recruiting 1 4 Months 40 Charles J Lowenstein, MD, Charles Lowenstein, MD, Shannon Kelley, BS, Thorsten Leucker, MD PhD 2020-06-18
A study of 254 nm UVC ray therapy in pharynx for asymptomatic to mild cases of coronavirus disease Coronavirus disease 19 infection standard of care alone, ultraviolet C therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Akshardeep Eye Hospital India 2020-06-11 CTRI/2020/06/025766 Phase Not Applicable Not yet recruiting 1 300 Dr Jagdeep Kakadia 2020-06-19
Clinical observation of the relieving effect of Kegan Liyan oral liquid on the throat symptoms of novel coronavirus pneumonia (COVID-19) in convalescence, suspected patients and other susceptible people Coronavirus disease 19 infection Kegan Liyan alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Dongguan People's Hospital China 2020-06-10 2020-12-31 ChiCTR2000033720 Phase 4 Clinical Not yet recruiting 1 6 Months 240 Chen Yiyun, Guan Ling, Hu Guanying 2020-06-22
SIDCOVID: A randomized, controlled clinical trial to determine the efficacy of siddha drugs in COVID-19 patients Coronavirus disease 19 infection Variable regimens including Amukkara choornam , Kabasura kudineer , Thalisathi choornam , adathodai manappagu Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Siddha India 2020-06-15 CTRI/2020/06/025763, SIDCOVID Phase 2 Clinical Not yet recruiting 1 150 G J Christian, Meenakumari R 2020-06-19
Effectiveness of lying face down in improving the outcome of COVID-19 patients Coronavirus disease 19 infection Awake self proning strategy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AIIMS Jodhpur India 2020-06-20 CTRI/2020/06/025804 Phase Not Applicable Not yet recruiting 1 120 Dr Maya Gopalakrishnan 2020-06-22
LUSCOVIDPREG: Descriptive and Evaluation Study of the Use of Pulmonary Ultrasound in the Initial Management of Pregnant Women in the Context of COVID-19 Coronavirus disease 19 infection lung ultrasound alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux De Marseille France 2020-06-15 2021-06-15 2020-30, 2020-A01303-36, LUSCOVIDPREG, NCT04432805 Phase Not Applicable Recruiting 1 12 Months 160 Jean-Olivier ARNAUD, Director, Julie BLANC, PH 2020-06-22
COPE: COPE - COVID-19 in Pregnancy and Early Childhood Coronavirus disease 19 infection biological samples, questionnaires and interviews alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sahlgrenska University Hospital Sweden 2020-06-02 2041-06-02 2020-02848 0604, COPE, NCT04433364 Phase Not Applicable Recruiting 26 252 Months 1200 Anna Sandström, MD PhD, Anna-Carin Wihlbäck, MD PhD, Anna-Karin Wikström, MD PhD, Daniel Axelsson, MD, Elisabeth Salekärr, research nurse, Emelie Ottosson, MD, Hanna Östling, MD PhD, Helena Fadl, MD PhD, Hugo Hessel, MD, Inger Sundström, MD PhD, Johanna Molin, MD, Karin Pettersson, MD PhD, Linda Hjertberg, MD, Magnus Domellöf, MD PhD, Maria Jonsson, MD PhD, Maria Svenvik, MD, Marie Blomberg, MD PhD, Marie Vikström Bohlin, MD PhD, Marie-Charlotte A Nilsson, Midwife, Matilda Friman-Mathiasson, MD, Mehreen Zaigham, MD PhD, Merit Kullinger, MD PhD, Ola Andersson, MD PhD, Ove Axelsson, MD PhD, Pihla Kuusela, MD PhD, Sandra Holmström, MD, Sebastian Brusell Gidlöf, MD PhD, Sofie Graner, MD PhD, Sophia Brismar Wendel, MD PhD, Susanne Hesselman, MD PhD, Verena Sengpiel, MD, PhD, Ylva Carlsson, MD PhD, Ylva Carlsson, MD, PhD, Åsa Leijonhufvud, MD PhD, Åsa Ponten, MD PhD 2020-06-22
COVIDOLIP: Lipid Metabolism in COVID-19 Severe Pneumonia Compared With Severe Pneumonia Caused by Other Pathogen Coronavirus disease 19 infection, Obesity, Sepsis, Viral pneumonia biological assays alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire Dijon France 2020-04-07 2020-05-07 COVIDOLIP, NCT04435223, NGUYEN AOIC 2020 Phase Not Applicable Completed 1 1 Month 62 2020-06-24
Effect of convalescent plasma in COVID-19 patients Coronavirus disease 19 infection Convalescent Plasma alone, Standard of Care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institute of Liver and Biliary Sciences, India India 2020-06-18 CTRI/2020/06/025803 Phase 3 Clinical Recruiting 3 400 Dr Meenu Bajpai, Dr Suresh kumar, Dr Vikas Dogra 2020-06-22
CoVPN 5001: A Study of Immune Responses to the Virus That Causes COVID-19 Coronavirus disease 19 infection sample collection alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Allergy and Infectious Diseases US, Peru, Zambia, Zimbabwe, Argentina, Brazil, South Africa, Tanzania, Botswana, Mexico, Kenya, Malawi, Mozambique 2020-06-11 2021-01-31 5UM1AI068614-14, COVPN 5001, CoVPN 5001, NCT04431414 Phase Not Applicable Recruiting 62 7 Months 800 CRS Coodinator, CRS Coordinator, CRS Coorindator, CRS Leader, Clinical Trials Manager, Protocol Team Leader, Will Hahn 2020-06-18
A case report to evaluate the efficacy of recombinant tissue plasminogen activator (rt-PA) and tocilizumab in patients with COVID-19 Coronavirus disease 19 infection, Respiratory failure, Thrombosis recombinant tissue plasminogen activator (rt-PA) alone, tocilizumab alone Male, Aged Adults (65-79 yrs), Elderly Adults (80 and over) University General Hospital of Larissa Phase Not Applicable Status not specified 0 1 2020-06-18
COVIT-EHPAD: COVID-19 and Vitamin D in Nursing-home Coronavirus disease 19 infection vitamin D3 alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Angers France 2020-03-15 2020-05-15 2020/67, COVIT-EHPAD, NCT04435119 Phase Not Applicable Completed 1 2 Months 96 Cédric ANNWEILER, MD, PhD 2020-06-22
A retrospective study to evaluate the viral kinetics and factors associated with viral clearance during lopinavir/ritonavir-based combination treatment in non-severe COVID-19 patients Coronavirus disease 19 infection lopinavir + ritonavir alone HIV protease inhibitor Shanghai Jiao Tong University Phase Not Applicable Status not specified 0 64 2020-06-21
The Utility of Camostat Mesylate in Patients With COVID-19 Associated Coagulopathy (CAC) and Cardiovascular Complications Blood clotting disorder, Coronavirus disease 19 infection, Deep vein thrombosis, Heart injury, Hypoxia, Lung embolism camostat mesylate alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yale University Ono Pharmaceutical Co Ltd US 2020-08-01 2021-07-30 2000028279, NCT04435015 Phase 1/Phase 2 Clinical Not yet recruiting 1 11 Months 200 Arpita Neogi, MS, Arya Mani, MD 2020-06-18
Local application of Povidone Iodine solution in nose and oral gargle for house hold contacts of COVID19 cases Coronavirus disease 19 infection gargle alone, povidone iodine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences, Mangalagiri India 2020-06-30 CTRI/2020/06/025928 Phase Not Applicable Recruiting 2 204 Dr Limalemla Jamir, Dr Sumita Shankar, Dr Vivekanand Kattimani 2020-06-19
Maraviroc in SARS-CoV-2 Coronavirus disease 19 infection, Viral pneumonia maraviroc alone CCR5 chemokine antagonist, CD4 agonist, HIV-1 gp120 protein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rhode Island Hospital US 2020-09-30 2020-12-31 1611471-1, NCT04435522 Phase 0 Clinical Not yet recruiting 1 3 Months 16 Anshul Parulkhar, MD, Neel S Belani, MD, Philip A Chan, MD 2020-06-19
Remote-by-Default Care in the COVID-19 Pandemic Coronavirus disease 19 infection interview alone, remote telephone conversation alone, remote video conversation alone, virtual ethnography alone University of Oxford Nuffield Trust, University of Plymouth UK 2020-06-01 2021-11-30 283196, NCT04435041 Phase Not Applicable No longer recruiting 1 18 Months 1 2020-06-22
A medical records based retrospective study of novel coronavirus pneumonia (COVID-19) patients Coronavirus disease 19 infection, Viral pneumonia Renmin Hospital of Wuhan University, West China Hospital Ministry of Science and Technology of the People´s Republic of China China 2020-06-18 2021-06-18 ChiCTR2000033782 Phase Not Applicable Not yet recruiting 1 12 Months 1400 Jirong Yue 2020-06-29
Compassionate Use of Opaganib in Patients With Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection high-flow nasal cannula alone, opaganib alone, standard of care alone, supplemental oxygen therapy alone Dihydroceramide delta 4 desaturase inhibitor, Sphingosine kinase 2 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) RedHill Biopharma Ltd, Shaare Zedek Medical Center Israel 2020-04-03 2020-05-15 0123-20- SZMC, NCT04435106 Phase Not Applicable Completed 1 1 Month 23 2020-06-30
Efficacy and Safety of Nitazoxanide for Post Exposure Prophylaxis of COVID-19 Coronavirus disease 19 infection nitazoxanide (Viranitta) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azidus Brasil Farmoquimica SA Brazil 2020-06-30 2020-08-31 NCT04435314, NITFQM0620OR Phase 2 Clinical Not yet recruiting 1 2 Months 200 Luciana Ferrara, Marcelo Fonseca, MD, Reginaldo Raimundo Fujita 2020-06-29
A case-study to evaluate the effects of using high dose oral and/or iv glutathione in the treatment of two patients with dyspnea secondary to COVID-19 pneumonia Coronavirus disease 19 infection, Dyspnea, Pneumonia glutathione alone Hudson Valley Healing Arts Center US Phase Not Applicable Status not specified 1 2 2020-06-19
Role of Herbal Immunomodulators in mild COVID-19 confirmed cases Coronavirus disease 19 infection Bresol plus Septilin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Himalaya Drug Co India 2020-06-19 CTRI/2020/06/025801, HDC/CP/PP/037/2020 Phase 2/Phase 3 Clinical Recruiting 1 40 Dr C R Jayanthi, Dr Palaniyamma D, Dr Soorya Narayan H 2020-06-22
Study on predictors of novel coronavirus pneumonia (COVID-19) elderly patients Coronavirus disease 19 infection, Sarcopenia, Viral pneumonia Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) West China Hospital Ministry of Science and Technology of the People´s Republic of China China 2020-06-18 2020-09-01 ChiCTR2000033781 Phase Not Applicable Not yet recruiting 1 2 Months 114 Jirong Yue, Yao Ma 2020-06-19
A Phase I/II study to evaluate its tolerability and activity in COVID-19 patients with hypoxemic respiratory failure receiving either non-invasive positive pressure ventilation (NIPPV) or mechanical ventilation (MV) Coronavirus disease 19 infection, Lung inflammation, Respiratory failure Rejuveinix alone, mechanical ventilation alone, non-invasive positive pressure ventilation alone, standard of care alone Reven Pharmaceuticals Inc Phase 1/Phase 2 Clinical Planned 0 2020-06-18
Inhaled Ciclesonide for Outpatients With COVID19 Coronavirus disease 19 infection ciclesonide alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) McGill University Health Center, Research Institute of the McGill University Health Centre Canada 2020-06-25 2021-03-25 2021-6696, NCT04435795 Phase 2/Phase 3 Clinical Not yet recruiting 1 9 Months 454 Nicole Ezer, Rola Hamed 2020-06-19
STORM: Repurposing Old Drugs TO Suppress a Modern Threat: COVID-19 STORM Coronavirus disease 19 infection doxycycline hyclate alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Temple University US 2020-06-22 2021-07-31 NCT04433078, STORM, THE STORM TRIAL Phase 2 Clinical Recruiting 2 13 Months 20 Arthur M Feldman, MD, PhD, Jamie L Garfield, MD 2020-06-25
A Phase I Study to Assess BAT-2020 in Hospitalized Patients Infected With SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection BAT-2020 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bio-Thera Solutions Ltd 2020-07-20 2021-01-18 BAT2020-001-CR, NCT04432766 Phase 1 Clinical Not yet recruiting 0 5 Months 174 2020-06-24
A medical records based study for analysis of Tongue Features of novel coronavirus pneumonia (COVID-19) Patients Coronavirus disease 19 infection, Viral pneumonia Dahuashan Cabin Hospital, Jiangxia District, Evidence-Based medicine center, Tianjin University of Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine China 2020-06-11 2020-06-19 ChiCTR2000033780, ChiMCTR2000003393 Phase Not Applicable No longer recruiting 1 500 Junhua Zhang, Wentai Pang 2020-06-19
Association of the Neutrophil/Lymphocyte Ratio With Clinical Complications and Mortality in COVID-19 Patients Coronavirus disease 19 infection oxygen therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Regional de Alta Especialidad de Ixtapaluca Hospital General de Mexico Mexico 2020-03-28 2020-05-05 NCT04434157, NR-09-2020 Phase Not Applicable Completed 1 1 Month 221 Christian Ramos Peñafiel,, Omar Ramos-Peñafiel 2020-06-22
Age and viral load in COVID-19 patients Coronavirus disease 19 infection, SARS coronavirus infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) St Marianna University School of Medicine Japan 2020-06-18 UMIN000040816 Phase Not Applicable Not yet recruiting 1 30 Tomohiro Katsuta 2020-06-19
An observational, retrospective study to explore the epidemiological information, clinical characteristics, therapeutic outcomes and temporal progression of laboratory findings in 2019-coronavirus disease (COVID-19) patients exposed to lopinavir Coronavirus disease 19 infection lopinavir alone The 6th People's Hospital of Hangzhou China Phase Not Applicable Status not specified 1 10 2020-06-18
Role of Ayurveda in Covid 19 management Coronavirus disease 19 infection Variable regimens including Agnikumara Rasa , Rasona kalka , Samshamani Vati , Shunthi churna , Vyaghryadi kashaya Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) National Health Mission India 2020-06-22 CTRI/2020/06/025800 Phase 2 Clinical Not yet recruiting 2 120 Adil Rais 2020-06-22
Physical Rehabilitation in ICU in ARDS Patients With COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome Rehabilitation program alone, Standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Koc University Turkey 2020-03-15 2020-06-11 2020.169.IRB1.037, NCT04435080 Phase Not Applicable Completed 1 2 Months 35 Ozden Ozyemisci Taskiran, Prof 2020-06-19
IDRA-COVID19: Ivermectin versus Combined Hydroxychloroquine and Antiretroviral Drugs (ART) Among Asymptomatic COVID-19 infection Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mahidol University Thailand 2020-07-31 2021-11-30 323/2563 (IRB3), IDRA-COVID19, NCT04435587 Phase 4 Clinical Not yet recruiting 1 16 Months 80 Rujipas Sirijatuphat, MD, Yupin Suputtamongkol, Yupin Suputtamongkol, MD 2020-06-24
A retrospective study on arbidol monotherapy was superior to lopinavir/ritonavir in treating COVID-19 Coronavirus disease 19 infection arbidol alone, lopinavir + ritonavir alone HIV protease inhibitor The Third People’s Hospital of Changzhou Phase Not Applicable Status not specified 0 50 2020-06-18
RESCUE1-19: Best Supportive Care With or Without Low Dose Whole Lung Radiation Therapy for the Treatment of COVID-19 Coronavirus disease 19 infection Low Dose Radiation Therapy (LDRT) alone, best supportive care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Emory University US 2020-06-12 2022-05-30 NCI-2020-04061, NCT04433949, P30CA138292, RAD5049-20, RESCUE1-19, STUDY00000781 Phase 3 Clinical Recruiting 1 23 Months 52 Allyson Anderson, Autumn Lunceford, Clayton B Hess, MD, MPH, Clayton B. Hess, MD,MPH, Mohammad K Khan, MD, PhD, Mohammad K. Khan, MD, PhD 2020-06-19
Ketotifen: as a Cardioprotective Agent in Breast Cancer Patients Receiving Anthracycline-containing Chemotherapy Breast tumor, Cardiotoxicity drug-induced, Coronavirus disease 19 infection anthracycline-containing chemotherapy alone, ketotifen alone Histamine H1 receptor antagonist Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Horus University (EG) Egypt 2019-01-14 2019-08-13 1890-1-2019, NCT04435028 Phase Not Applicable Completed 1 7 Months 111 Hosny ahmed elewa 2020-06-22
The effect of vitamin C and E in the treatment and clinical course of patients with SARS-COV2 (COVID-19) Coronavirus disease 19 infection hydroxychloroquine diet alone, Variable regimens including hydroxychloroquine sulfate , lopinavir + ritonavir , vitamin C , vitamin E HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Isfahan University of medical Sciences Iran 2020-04-20 IR.MUI.MED.REC.1399.047, IRCT20180425039414N3 Phase 2/Phase 3 Clinical No longer recruiting 1 80 Atousa Hakamifard, Shghayegh Haghjoo Javanmard 2020-06-19
A multinational registry analysis of the use of hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19 Coronavirus disease 19 infection chloroquine alone, hydroxychloroquine alone, macrolide alone, chloroquine plus hydroxychloroquine Harvard Medical School Phase Not Applicable Status not specified 0 96032 2020-06-18
Evaluating the Efficacy and Safety of Bromhexine Hydrochloride Tablets in Treating Pediatric novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Standard treatment alone, bromhexine hydrochloride alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Children's Hospital of Zhejiang University School of medicine Zhejiang Wanbang Pharmaceutical Co Ltd China 2020-02-12 2020-12-31 ChiCTR2000033774 Phase 4 Clinical Not yet recruiting 1 10 Months 30 Qingqing Wang, Zhimin Chen 2020-06-19
Treatment With Investigational Convalescent Plasma and Measure Antibody Levels in Patients Hospitalized With COVID-19 Coronavirus disease 19 infection Anti-SARS-CoV-2 convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of New Mexico US 2020-04-28 2025-04-28 20-227, NCT04434131 Phase 2 Clinical Recruiting 1 60 Months 30 Greg Mertz, MD, Michelle Harkins, MD 2020-06-19
A retrospective, single center study on treatment response of tocilizumab in COVID-19 Coronavirus disease 19 infection tocilizumab alone Huazhong University of Science and Technology Phase Not Applicable Status not specified 0 15 2020-06-18
Clinical study on the effect of Keganliyan oral liquid on the relief of pharyngeal symptoms of novel coronavirus pneumonia (COVID-19) in convalescence, suspected patients and other susceptible populations Coronavirus disease 19 infection Keganliyan liquid alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Maoming Affiliated Hospital of Southern Medical University China 2020-06-15 2020-12-31 ChiCTR2000033745 Phase 4 Clinical Not yet recruiting 1 6 Months 240 Guanying Hu, Yaocai Li 2020-06-19
A Real-life, case-series study to report preliminary data obtained with anti-complement C5 therapy with eculizumab in COVID-19 patients admitted to intensive care unit (ICU) of ASL Napoli 2 Nord Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia eculizumab alone, enoxaparin sodium alone, non-invasive ventilation alone, vitamin C alone, Variable regimens including ceftriaxone , hydroxychloroquine , lopinavir + ritonavir Complement C5 factor inhibitor, HIV protease inhibitor, Low molecular weight heparin Santa Maria delle Grazie, Pozzuoli Phase 4 Clinical Status not specified 0 4 2020-06-25
A study for long-term prognosis in hospitalized novel coronavirus pneumonia (COVID-19) patients Coronavirus disease 19 infection China-Japan Friendship Hospital, Wuhan Jinyintan Hospital China Academy of Chinese Medical Sciences China 2020-05-01 2021-05-01 ChiCTR2000033723 Phase Not Applicable Not yet recruiting 1 12 Months 2500 LIU YING, Zhang DY, Huang CL, Cao B 2020-06-19
Seroconversion Among Staff at a Large Acute Care Hospital in Denmark During the COVID-19 Pandemic Coronavirus disease 19 infection biological sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nordsjaellands Hospital Nykøbing Falster County Hospital, University of Oxford Denmark 2020-03-27 2025-08-01 JOURNAL-NR.: H-20022312, NCT04431310 Phase Not Applicable Recruiting 2 64 Months 300 Fischer, Gry St-Martin, md, Thea K Fischer, Thea K Fischer, professor 2020-06-19
CARAVAN: Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of Remdesivir (GS-5734) in Participants From Birth to < 18 Years of Age With Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Gilead Sciences Inc Europe, US 2020-06-30 2020-12-31 2020-001803-17, CARAVAN, GS-US-540-5823, NCT04431453 Phase 2/Phase 3 Clinical Not yet recruiting 1 6 Months 52 Gilead Clinical Study Information Center, Gilead Study Director 2020-06-30
An observational study to evaluate the pharmacokinetics of favipiravir in patients with severe COVID-19 who were admitted to the intensive care unit and placed on mechanical ventilation Coronavirus disease 19 infection favipiravir alone RNA polymerase inhibitor Kobe City Medical Center General Hospital, Kobe Gakuin University Phase Not Applicable Status not specified 0 7 2020-06-18
Assessment of the Effectiveness of Vibroacoustic Therapy for Respiratory Failure Caused by COVID 19 Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure, Viral pneumonia VibroLUNG alone, vibroacoustic therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Astana Medical University Kazakhstan 2020-03-22 2021-02-01 ASTANAMU, NCT04435353 Phase Not Applicable Recruiting 2 10 Months 200 Irina Mukatova, MD, Irina Mukatova, PhD, Ivan Vahrushev, Dr, Mukatova Irina 2020-06-19
Impact of Cancellation of Non-urgent Surgical Cases on Patients During the COVID-19 Pandemic Coronavirus disease 19 infection Mansoura University Egypt 2020-07-01 2020-12-01 NCT04433312, SURG RES COL 2 Phase Not Applicable Not yet recruiting 1 5 Months 10000 Ahmed M Elsheikh, MD,MBA,CMQOE, Hosam Hamed, MD, MSc, PhD, Mostafa M Shalaby, MD, MSc, PhD, Mostafa Shalaby, MD, MSc, PhD 2020-06-25
Study to Assess VPM-1002 in Reducing Hospital Admissions and/or Severe Respiratory Infectious Diseases in Elderly in COVID-19 Pandemic Coronavirus disease 19 infection, Respiratory tract infection VPM-1002 alone Listeriolysin stimulator Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Max-Planck Gesellschaft zur Förderung Der Wissenschaften eV, Vakzine Projekt Management GmbH FGK Clinical Research GmbH Germany 2020-06-30 2021-05-31 2020-001675-33, NCT04435379, VPM1002-DE-3.07COV Phase 3 Clinical Recruiting 4 11 Months 2038 Clinical Trial Information, Leander Grode, Dr. rer. nat. 2020-06-26
PEDONCOVID: COVID-19 in Pediatric Oncology and Hematology Centers in France Cancer, Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Caen University Hospital France 2020-04-27 2023-04-27 20-065, NCT04433871, PEDONCOVID Phase Not Applicable Recruiting 1 36 Months 300 Jérémie M Rouger-Gaudichon, MD, PhD, Jérémie Rouger-Gaudichon, MD, PhD 2020-06-19
PrimaryCovCare: Ambulatory healthcare models and processes during the ongoing SARS-CoV-2 pandemic (COVID-19) Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Heidelberg Germany 2020-06-17 DRKS00022224, PrimaryCovCare, S-418/2020 Phase Not Applicable Recruiting 1 1000 Amanda Breckner, Catharina Roth, Michel Wensing, Sandra Stengel 2020-06-19
To evaluate the efficacy of diammonium glycyrrhizinate in combination with vitamin C in patient with COVID-19 Coronavirus disease 19 infection diammonium glycyrrhizinate plus vitamin C Female National Institute of Allergy and Infectious Diseases, National Institute of General Medical Sciences, National Institutes of Health, US Department of Health and Human Services Phase Not Applicable Status not specified 0 1 2020-06-18
A clinical trial of VLP vaccine (COVID-19), Saiba for the potential prevention of SARS-CoV-2 infection (COVID-19) Coronavirus disease 19 infection VLP vaccine (COVID-19), Saiba alone COVID19 Spike glycoprotein modulator Saiba GmbH 2020-12-31 Phase Not Applicable Planned 0 2020-06-18
IFORS: A Study to Compare the Efficacy and Safety of Different Doses of Ivermectin for COVID-19 Coronavirus disease 19 infection, Respiratory disease, Respiratory tract infection ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundação Universidade Federal De São Carlos Brazil 2020-07-01 2021-07-01 IFORS, IFORS, NCT04431466 Phase 2 Clinical Not yet recruiting 1 12 Months 64 Henrique Pott Junior, Henrique Pott Junior, MD PhD 2020-06-19
Cardiovascular Implications of COVID-19 Coronavirus disease 19 infection, Heart injury [1-13C] pyruvate alone, multiparametric cardiac magnetic resonance imaging (CMR) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Texas Southwestern Medical Center 2020-06-30 2020-10-31 NCT04435457, STU-2020-0359 Phase Not Applicable Not yet recruiting 0 4 Months 70 Carolyn Kelly, RN, MPH, CCRC, Justin L Grodin, MD, MPH 2020-06-19
To observe the effect of Siddha formulation Kabasura kudineer in COVID 19 patients Coronavirus disease 19 infection Kabasura kudineer alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Government Theni Medical College and Hospital, Ministry of Ayush India 2020-06-24 CTRI/2020/06/025874 Phase 2 Clinical Not yet recruiting 1 60 Dr C Anbarasi, Dr P Sankararaj 2020-06-19
A phase II/III study of COVAX-19 in prevention of COVID-19 Coronavirus disease 19 infection Covax-19 alone Coronavirus spike glycoprotein inhibitor Vaxine Pty Ltd 2020-12-31 Phase 2/Phase 3 Clinical Planned 0 2020-06-19
Study of AYUSH KWATH in quarantine persons Coronavirus disease 19 infection Ayush Kwath alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Dr. Sarvepalli Radhakrishnan Rajasthan Ayurveda University India 2020-06-17 CTRI/2020/06/025779 Phase Not Applicable Not yet recruiting 1 50 Prof Dr Abhimanyu Kumar 2020-06-19
A case series, retrospective study on 18F-FDG PET/CT findings of COVID-19 infection Coronavirus disease 19 infection, Respiratory disease 18F-FDG alone, positron emission tomography/computed tomography alone Chang Gung Memorial Hospital, Huazhong University of Science and Technology, Hubei Province Pharmaceutical Industry Research Institute China Phase Not Applicable Status not specified 1 4 2020-06-18
A retrospective, multicenter, cohort study to describe the association between use of hydroxychloroquine, with or without azithromycin, and clinical outcomes among hospital inpatients diagnosed with coronavirus disease 2019 (COVID-19) Coronavirus disease 19 infection azithromycin alone, hydroxychloroquine alone, azithromycin plus hydroxychloroquine UAlbany School of Public Health US Phase Not Applicable Status not specified 1 1438 2020-06-18
A prophylactic interventional study to determine the possible protective effect of Siddha Polyherbal formulation Kabasura Kudineer / Nilavembu kudineer against the COVID-19 on intermittent, month-long consumption by Highrisk population and frontline workers in Tamil Nadu, India Coronavirus disease 19 infection Standard of Care alone, Kabasura Kudineer plus Nilavembu kudineer National Institute of Siddha India 2020-06-15 CTRI/2020/06/025769 Phase 2/Phase 3 Clinical Not yet recruiting 1 500 Dr G J Christian, Dr R Meenakumari 2020-06-19
TOCCIP: COVID-19 Critically Ill Patients Evolution After Medical Transport by Train From Paris Intensive Care Units to West of France Intensive Care Units Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rennes University Hospital France 2020-06-30 2020-09-30 35RC20-3091-TOCCIP, NCT04433325, TOCCIP Phase Not Applicable Not yet recruiting 2 3 Months 150 Anne Ganivet, Arnaud THILLES, Benoît Painvin, Nicolas Mevel, Stéphane ERHMANN 2020-06-19
Impact of COVID-19 on Laboratory Professionals-Early Evidences from a Survey at a Clinical Chemistry Laboratory in a Developing Country Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Aga khan University Pakistan 2020-06-04 2020-06-14 ChiCTR2000033899 Phase Not Applicable No longer recruiting 1 64 Sibtain Ahmed 2020-06-19
An open-label, Randomized Controlled Clinical trial to Evaluate the Safety and Efficacy of selected Siddha formulations in patients diagnosed with COVID-19 Coronavirus disease 19 infection siddha formulation alone, Variable regimens including Kabasura kudineer , Nellikai Ilagam , amukkara churnam Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chengalpattu Medical College, National Institute of Siddha India 2020-06-20 CTRI/2020/06/025768 Phase 2 Clinical Not yet recruiting 1 200 Dr G J CHRISTIAN, Dr MEENAKUMARI R 2020-06-19
Natural Language Processing (NLP) Analysis of Free Text Notes to Investigate Coronavirus (COVID-19) Coronavirus disease 19 infection, Renal injury, Thromboembolism electronic health record (EHR) alone, natural language processing techniques alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cambridge University Hospitals NHS Foundation Trust University of Cambridge UK 2020-07-31 2021-07-31 A095625, NCT04432961 Phase Not Applicable Not yet recruiting 1 12 Months 200 Dr Sapna Trivedi 2020-06-19
An interim Doherty Report on SARS-CoV-2 antibodies based on Wondfo test (serology-based COVID-19 POC test) Coronavirus disease 19 infection Wondfo test (serology-based COVID-19 POC test) alone Cellmid Ltd Australia Phase Not Applicable Status not specified 1 137 2020-06-18
The Use of Lung Ultrasonography in COVID-19 Patients Coronavirus disease 19 infection, Respiratory failure mechanical ventilator settings and position alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gaziosmanpasa Taksim Research and Education Hospital Turkey 2020-05-26 2020-06-26 GAZIOSMANPASA, NCT04432051 Phase Not Applicable Recruiting 1 1 Month 100 SİBEL BEKTAŞ 2020-06-19
Community Health Workers Against COVID19 Anxiety disorder, Coronavirus disease 19 infection community health worker support alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitaet Gent Belgium 2020-05-21 2020-10-30 BC-07744., NCT04426305 Phase Not Applicable Recruiting 1 5 Months 140 2020-06-19
A Study of Favipiravir in Patients with Mild to Moderate Coronavirus Disease (COVID-19) Coronavirus disease 19 infection favipiravir alone, supportive care  alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Cipla Ltd India 2020-06-17 CP/04/20, Version No. 1.0, CTRI/2020/06/025799 Phase 3 Clinical Not yet recruiting 8 156 Dr Ameet Dravid, Dr Anand Kumar, Dr Atul Patel, Dr Jaideep Gogtay, Dr Meenakshi Bhattacharya, Dr Raja Dhar, Dr Rohidas Borse, Dr Sandesh Sawant, Dr Shreepad Bhat, Dr Vasant Nagvekar, Mr Abhijit Vaidya 2020-06-19
ICON STUDY: A Clinical trial to establish the appropriate line of management of non-muscle invasive bladder cancers who have had their intravesical BCG therapy interrupted Bladder cancer, Coronavirus disease 19 infection BCG alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences, All India Institute of Medical Sciences Bhubaneswar, Christian Medical College, Vellore, India, Jawaharlal Institute of Postgraduate Medical Education Research, Postgraduate Institute of Medical Education and Research, king george's medical university India 2020-06-18 CTRI/2020/06/025798, ICON STUDY Phase 4 Clinical Not yet recruiting 10 70 Amlesh Seth, Aneesh Srivastava, Dr Tushar Aditya Narain, Gautam Ram Choudhary, Manikandan Ramanidhatharan, Prasant Nayak, Sameer Trivedi, Santosh Kumar, Satya Narayan Sankhwar, Shrawan Kumar Singh, Tushar Aditya Narain 2020-06-19
Quality of Life During COVID-19 Lockdown Coronavirus disease 19 infection, Pain Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Cancer Institute, Jhajjar, AIIMS India 2020-06-13 CTRI/2020/06/025797 Phase Not Applicable Not yet recruiting 1 Anuja Pandit 2020-06-19
Effect of aragwadhadi kwath (kadha in Hindi) in treatment of mild coronavirus disease Coronavirus disease 19 infection aragwadhadi kwath alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Sanjivani Aryuvedic Centre India 2020-06-15 CTRI/2020/06/025796 Phase Not Applicable Not yet recruiting 1 90 Dr Sunil Panjwani, Vaidhya Tushar Trivedi 2020-06-19
Effects of Lockdown during Corona Pandemic on Children with Neurodevelopmental Disorders-A Questionnaire Based Survey Attention deficit hyperactivity disorder, Autism, Coronavirus disease 19 infection question based survey alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs) Army Hospital Research and Referral India 2020-06-15 CTRI/2020/06/025795 Phase Not Applicable Not yet recruiting 1 150 J N Goswami, Shuvendu Roy 2020-06-19
Effect of anakinra in treatment of COVID-19 Coronavirus disease 19 infection anakinra, Persisgen alone, recommended COVID-19 treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Persisgen Par Co Iran 2020-06-21 IR.SBMU.PHARMACY.REC.1399.051, IRCT20120703010178N20 Phase 3 Clinical Recruiting 1 30 Amir Behnam Kharazmi, Amir Hossein Karagah, Mohammad Sistanizad, Omid Moradi 2020-06-23
A Study to Assess the Effect of Beckman Coulter SARS-CoV-2 Antibody Test in Patients with COVID-19 Coronavirus disease 19 infection Beckman Coulter SARS-CoV-2 antibody test alone Henry Ford Health System Phase Not Applicable Status not specified 0 2020-06-18
PRO-SERO-COV: Serological Response to SARS-Cov-2 Virus in Personnel of the Institut Bergonie in the Context of the COVID-19 Pandemic Coronavirus disease 19 infection blood sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institut Bergonie France 2020-06-30 2021-12-31 2020-A01355-34, IB 2020-01, NCT04426006, PRO-SERO-COV Phase Not Applicable Not yet recruiting 1 18 Months 1000 Brice RICHEZ, MD, Simone MATHOULIN-PELISSIER, MD, PhD 2020-06-21
TA/SARS-Cov2: Is Adipose Tissue a Reservoir for SARS-Cov2 Spread in Covid-19 Patients? Coronavirus disease 19 infection biopsies of subcutaneous adipose tissue alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire De Nice France 2020-07-01 2021-07-09 20-PP-15, NCT04427878, TA/SARS-Cov2 Phase Not Applicable Not yet recruiting 1 12 Months 5 Berengère Chignon-Sicard, PH, Vanina OLIVERI, PM 2020-06-21
CIO: Impact of COVID-19 Lockdown on Obesity and Eating Behaviors Acute stress disorder, Anxiety disorder, Binge eating disorder, Coronavirus disease 19 infection, Depression, Obesity Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospices Civils De Lyon France 2020-06-16 2020-09-16 2020-A01616-33, 69HCL20-0516, CIO, NCT04431284 Phase Not Applicable Recruiting 1 3 Months 46 Emmanuel DISSE, MD, Martine LAVILLE, MD 2020-06-30
ABACCuS: Antibody-Level Based Analysis of COVID Convalescent Serum Coronavirus disease 19 infection COVID-19 convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) William Beaumont Hospitals US 2020-06-30 2021-08-31 2020-198, ABACCuS, NCT04432272 Phase 2 Clinical Not yet recruiting 1 14 Months 500 Matthew Sims, MD, Matthew Sims, MD PhD, Maureen Cooney, RN, BSN 2020-06-19
Favipiravir effectiveness in patients undergoing COVID19 Acute respiratory distress syndrome (ARDS) Coronavirus disease 19 infection, Respiratory distress syndrome favipiravir alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Masih Daneshvari Hospital Iran 2020-03-20 2020-05-21 IR.SBMU.NRITLD.REC.1399.041, IRCT20150107020592N26 Phase 3 Clinical Completed 1 2 Months 20 DR Reza Masoodi, Seyed Mohammad Reza Hashemian, Seyyed Mohammadreza Hashemian 2020-06-19
ANIF1 effect on COVID-19 Coronavirus disease 19 infection ANIF1 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mazandaran University of Medical Sciences Iran 2020-06-09 IR.MAZUMS.REC.1399.067, IRCT20190727044343N3 Phase 2/Phase 3 Clinical No longer recruiting 1 60 Lotfollah Davoodi 2020-06-23
Prone Positioning on Admission for Hospitalized COVID-19 Pneumonia Protocol Coronavirus disease 19 infection, Viral pneumonia Prone Positioning alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Poudre Valley Health System US 2020-06-30 2020-12-31 20-6034, NCT04424797 Phase Not Applicable Recruiting 3 6 Months 100 Adam Jaskowiak, Lucie Uncapher, Lucie Uncapher, MD, Research Manager, Sara Twombly, MACI CCRC 2020-06-21
Treatment of COVID-19 whit vitamin A Coronavirus disease 19 infection vitamin A, Ovigel Company alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ghoum University of Medical Sciences Iran 2020-05-04 2020-06-13 IR.MUQ.REC.1399.045, IRCT20200314046774N1 Phase 3 Clinical Completed 1 1 Month 94 Majid Farhadifard 2020-06-22
Combined effects of Extracts on Covid-19 Coronavirus disease 19 infection herbal teas alone Shiraz University of Medical Sciences Iran 2020-06-21 IR.SUMS.REC.1399.179, IRCT20200508047345N1 Phase Not Applicable No longer recruiting 1 100 Mohammad Jamal Saharkhiz 2020-06-24
I-GLOBAL: Validation of an Immunochromatographic Assay for IgG/IgM Antibodies to 2019- nCoV Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia IgG/IgM rapid test cassette alone, immunochromatographic assay alone, polymerase chain reaction alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) European Institute of Oncology ASST Papa Giovanni XXIII, Azienda Ospedale Niguarda Cà Granda, Company Socio - Cremona Territorial Health, Fondazione IRCCS Istituto Neurologico Carlo Besta Italy 2020-04-15 2020-12-31 I-GLOBAL, I-GLOBAL, NCT04434417 Phase Not Applicable Recruiting 5 8 Months 1000 Alberto Zambelli, MD, Antonio Marra, MD, Atanasio Nonis, PhD, Daniele Generali, MD, Francesco Di Meco, MD, Giuseppe Curigliano, MD, Giuseppe Curigliano, MD, PhD, Salvatore Siena, MD 2020-06-18
Prone position effectiveness in Non invasive ventilation of covid-19 patients undergoing respiratory failure Coronavirus disease 19 infection, Respiratory failure non-invasive ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shahid Beheshti University of Medical Sciences Iran 2020-03-20 IR.SBMU.NRITLD.REC.1399.009, IRCT20150107020592N25 Phase 3 Clinical No longer recruiting 1 30 Seyed Mohammad Reza Hashemian, Seyed Mohammad reza hashemian, Seyyed Mohammadreza Hashemian 2020-06-23
Treatment of Covid-19 patients with convalescent plasma Coronavirus disease 19 infection convalescent covid-19 plasma therapy alone Iranian blood transfusion organization Iran 2020-05-25 IR.TMI.REC.1399.003, IRCT20200525047562N1 Phase 3 Clinical Recruiting 2 100 Hamid Reza Kouhpayeh, Mandana Pouladzadeh, Peyman Eshghi, Saeed Mohammadi, Shamsi Okati 2020-06-22
A Gamified Network for Surgical Education During COVID-19: A Randomized Controlled Trial Coronavirus disease 19 infection Peer-learning alone, Peer-learning with expert feedback alone, Self-learning alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universite De Montreal 2020-06-30 2020-06-30 CERSES 20-068-D, NCT04425499 Phase Not Applicable Not yet recruiting 0 60 Érica Patocskai, Assistant professor 2020-06-22
Recruit Blood Donors Via SMS During Epidemic of COVID-19 #Second Repeat Trial# Coronavirus disease 19 infection blood donation SMS alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Guangzhou Blood Center China 2020-06-13 2020-06-30 NCT04431180, RECRUIT BLOOD DONORS VIA SMS 3 Phase Not Applicable Recruiting 1 403535 2020-06-23
Covid-No-Thank you: Data evaluation of an online symptom and risk detection application for COVID-19 research Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Orthopädische Universitätsklinik Friedrichsheim gGmbH University Hospital Magdeburg Germany 2020-04-29 65/20, Covid-No-Thank you, DRKS00022185, U1111-1252-6946 Phase Not Applicable Recruiting 1 10000 Dietmar Urbach, Gutingi-Medical GmbH 2020-06-22
The effect of pentaglobin in the treatment of critically ill patients with COVID-19 Coronavirus disease 19 infection, Respiratory failure pentaglobin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-03-20 IR.SBMU.NRITLD.REC.1399.014, IRCT20150107020592N27 Phase 3 Clinical No longer recruiting 1 60 Dr Seyyed Mohamadreza Hashemian, Seyyed Mohammadreza Hashemian 2020-06-24
Proper Nutrition And Its Relation To Oral Diseases In Covid -19 Era Coronavirus disease 19 infection, Mouth disease Proper diet alone, Vitamins alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) October University for Modern Sciences and Arts Egypt 2020-06-08 2020-06-28 12345678, NCT04434014 Phase Not Applicable Recruiting 1 300 Lecturer Mona abdelmoteleb, Samah Kamel, A .Prof, Samah Mohamed Kamel, A.Prof, Samah Mohamed Kamel, associate professr, lecturer Mona Abdelmoteleb 2020-06-18
ASTANA: Oncological Surgery in Times of COVID-19: Effectiveness of Preoperative Screening for Sars-Cov-2 Cancer, Coronavirus disease 19 infection SARS-CoV-2 PT-PCR test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Brasileiro de Controle do Cancer Brazil 2020-05-11 2020-12-31 33467320.0.0000.0072, ASTANA, NCT04434261 Phase Not Applicable Recruiting 1 7 Months 1500 Alayne Yamada, PhD, Andre Lopes, MD 2020-06-18
Evaluation of the effectiveness of traditional medicine combination based on the Ferula assa-foetida gum - Tragacanth in Participants with Moderate to Severe Coronavirus Disease (COVID-19) Coronavirus disease 19 infection Ferula assa-foetida gum plus tragacanth Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mashhad University of Medical Sciences Iran 2020-06-19 IR.MUMS.REC.1399.285, IRCT20200607047675N1 Phase 3 Clinical Recruiting 1 100 Dr. Amin Bojdy, Dr. HamidReza Bahrami Taghanaki, Dr. Majid Jafarinejad, Nayereh Esmaeilzadeh, ِDr. Mohsen Tafaghdi 2020-06-19
Treatment of Severe and Critical COVID-19 Pneumonia With Convalescent Plasma Coronavirus disease 19 infection, Viral pneumonia anti sars-cov 2 convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) American British Cowdray Medical Center Mexico 2020-06-19 2020-09-30 ABC-20-14, NCT04432103 Phase 2 Clinical Recruiting 1 3 Months 36 Benjamín Valente, MD MSc DTMH, Francisco Moreno, MD, Irma Hoyo, MD PHD, Paulina Trápaga, MBE 2020-06-19
An interventional study to evaluate the safety and immune response of a vaccine against Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2, the virus that causes COVID-19 infection) when given to healthy adult participants Coronavirus disease 19 infection protein subunit vaccine (molecular clamp, COVID-19), University of Queensland alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University of Queensland Coalition for Epidemic Preparedness Innovations Australia 2020-07-14 ACTRN12620000674932p, UQ-1-SARS-CoV-2-Sclamp Phase 1 Clinical Recruiting 1 120 Dr Paul Griffin 2020-06-26
CoPE-HCP: COVID19 and Physical and Emotional Wellbeing of HCP Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychotic disorder Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Queen Mary University of London UK 2020-06-30 2021-06-30 284686, CoPE-HCP, NCT04433260 Phase Not Applicable Not yet recruiting 1 12 Months 1050 Ajay Gupta, MD, PhD, Ajay Gupta, MD,PhD 2020-06-18
ACCOLADE: Amnion cells for COVID-19 related respiratory failure Coronavirus disease 19 infection, Respiratory failure amniotic epithelial cells (hAECs) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Monash Health Australia 2020-06-29 ACCOLADE, ACTRN12620000676910p Phase 1/Phase 2 Clinical Not yet recruiting 1 40 A/Prof Rebecca Lim, Prof Yahya Shehabi 2020-06-19
Efficacy of Pentoxifylline as Add-on Therapy in COVID-19 Patients Coronavirus disease 19 infection pentoxifylline SR alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University of Sadat City Egypt 2020-06-13 2020-08-30 NCT04433988, RC-6-2020 Phase 1/Phase 2 Clinical Not yet recruiting 1 2 Months 200 Mahmoud S Abdallah, PhD 2020-06-18
Perceptions, Representations and Experiences of Septic Isolation of Hospitalized Patients for COVID-19 Infection Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Intercommunal Creteil France 2020-07-01 2020-07-15 ISOCOV, NCT04432922 Phase Not Applicable Not yet recruiting 1 15 Alice RAFFETIN, MD 2020-06-23
In-utero Vascular Accidents in Neonates From COVID-19 Infected Mothers Coronavirus disease 19 infection, Fetal growth restriction, Limb development disorder, Premature labor, Spontaneous abortion SARS-CoV-2 antibody testing alone Healthy volunteers accepted University of Colorado, Denver, US US 2020-07-31 2022-07-31 20-1399, NCT04431869 Phase Not Applicable Not yet recruiting 1 24 Months 200 Jose L Diaz-Miron, MD 2020-06-25
Validation of a Rapid Quantitative Test for Loss of Smell in COVID-19 Subjects Coronavirus disease 19 infection, Dysomia olfactory device alone, rapid quantitative olfactory smell test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yale University US 2020-06-15 2020-10-01 2000028259, NCT04431908 Phase Not Applicable Not yet recruiting 1 3 Months 250 R Peter Manes, MD, FACS 2020-06-18
An Open-Label Randomized Controlled, Proof-of-Concept (PoC) Study to Evaluate the Safety and Efficacy of selected Siddha formulations in patients diagnosed with COVID-19 Coronavirus disease 19 infection Variable regimens including Amukkara choornam , KS kudineer , Nellikkai ilagam Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Siddha India 2020-06-15 CTRI/2020/06/025762 Phase 3 Clinical Not yet recruiting 1 200 Dr G J Christian, Dr R Meenakumari 2020-06-18
Population based cross-sectional study for COVID 19 prophylaxis with Polyherbal Siddha formulation Kabasura Kudineer / Nilavembu kudineer in containment zones and non containment zones during 2020 pandemic in Tamil Nadu, South India Coronavirus disease 19 infection Kabasura Kudineer / Nilavembu kudineer alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) National Institute of Siddha India 2020-06-15 CTRI/2020/06/025761 Phase Not Applicable Not yet recruiting 1 10000 Dr G J Christian, Dr R Meenakumari 2020-06-18
A clinical trial to study the effect of drug named Sofosbuvir in hospitalized patients with COVID 19 Coronavirus disease 19 infection hydroxychloroquine plus sofosbuvir Hepatitis C virus NS5B polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Vijaya Medical and Educational Trust India 2020-06-17 CTRI/2020/06/025760 Phase 3 Clinical Not yet recruiting 1 50 Babu N 2020-06-19
PoWerS: COVID-19 Psychological Wellbeing for Healthcare Students Coronavirus disease 19 infection Psychological wellbeing for healthcare workers alone Healthy volunteers accepted University of Nottingham 2020-06-13 2020-12-30 NCT04429828, POWERS_JUNE2020, PoWerS Phase Not Applicable Not yet recruiting 0 6 Months 45 Holly Blake, PhD 2020-06-19
Hydroxychloroquine May Reduce Risk of COVID-19 Infection in Rheumatoid Arthritis Patients Coronavirus disease 19 infection, Rheumatoid arthritis glucocorticoid therapy alone, Variable regimens including hydroxychloroquine , leflunomide , methotrexate , sulfasalazine Dihydroorotate dehydrogenase inhibitor, Protein tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University of Sadat City Egypt 2020-03-20 2020-06-20 IRB: RC-5-2020, NCT04434118 Phase Not Applicable Recruiting 1 3 Months 600 2020-06-18
CAHMP-ED: COVID-19 and the Healthy Minds Program for Educators Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy Minds Program Foundations Training alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Wisconsin-Madison Center for Healthy Minds, Chan Zuckerberg Initiative, Healthy Minds Innovations 2020-06-10 2022-06-30 2020-0533, A171600, CAHMP-ED, EDUC/COUNSELING PSYCH, NCT04426318, PROTOCOL APPROVAL 6/4/2020 Phase Not Applicable Not yet recruiting 0 24 Months 400 Corrina Frye, Simon B Goldberg, PhD 2020-06-17
A clinical study of nelfinavir in combination with amodiaquine for the treatment of COVID-19 Coronavirus disease 19 infection amodiaquine plus nelfinavir HIV protease inhibitor, HIV-1 protease inhibitor Norwegian University of Science and Technology (NTNU) Phase Not Applicable Planned 0 2020-06-17
Effect of Auriculotherapy in treatment of COVID-19 Coronavirus disease 19 infection orchicotherapy alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shahid Sadoughi University of Medical Sciences and Health Services Iran 2020-04-28 IR.SSU..REC.1399.030, IRCT20180608040007N2 Phase Not Applicable No longer recruiting 1 70 Dr. Masoud Mirzaei, Maryam Mohammadi, Mohammad Bagher Khani 2020-06-30
Dornase Alpha for the Treatment of COVID-19 Coronavirus disease 19 infection dornase alfa alone Deoxyribonuclease I stimulator, Deoxyribonuclease stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Acibadem University The Scientific and Technological Research Council of Turkey Turkey 2020-05-25 2020-09-25 8820, NCT04432987 Phase 2 Clinical Recruiting 1 4 Months 60 Ercument Ovalı, MD, Ercument Ovalı, Prof. 2020-06-18
Effect of the combination of BCc1 and Hep-S on hospitalized COVID-19 patients Coronavirus disease 19 infection BCc1 alone, Hep-s alone, BCc1 plus Hep-s Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shahid Beheshti University of Medical Sciences, Sodour Ahrar Shargh Knowledge-based Company Iran 2020-05-21 IR.SBMU.CRC.REC.1399.001, IRCT20170731035423N2 Phase 3 Clinical Recruiting 1 120 Alireza Fatemi, Maryam Hafizi, محمد اسماعیل اکبری 2020-06-30
Effect of Atazanavir/Ritonavirin treatment of COViD-19 Coronavirus disease 19 infection atazanavir sulfate + ritonavir (HIV infection), Mylan Laboratories alone HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Alborz University of Medical Science Iran 2020-06-14 IR.ABZUMS.REC.1399.065, IRCT20200504047298N1 Phase 3 Clinical Recruiting 1 100 Zeinab Siami 2020-06-18
ELIKYA COVID: Impact of COVID-19 Infection During Pregnancy on Newborns and Young Children Coronavirus disease 19 infection, Pregnancy disorder nasal swab test alone, serology test alone Centre Hospitalier Universitaire Saint Pierre Institute for Medical Immunology (IMI), Laboratoire Hospitalier Universitaire de Bruxelles Belgium 2020-06-25 2024-06-30 ELIKYA COVID, ELIKYA COVID, NCT04432779 Phase Not Applicable Not yet recruiting 2 48 Months 3000 Julie Belhomme, MD, Tessa Goetghebuer, MD, Tessa Goetghebuer, MD PhD, Tessa Goetghebuer, MD, PhD 2020-06-23
HIBISCUS: A phase II/III pivotal, randomized, placebo-controlled Traumakine study in severely ill COVID-19 patients Adult respiratory distress syndrome, Coronavirus disease 19 infection, Influenza virus infection FP-1201 alone CD73 agonist, Interferon beta ligand Faron Pharmaceuticals Ltd US HIBISCUS Phase 2/Phase 3 Clinical Planned 1 350 Prof. Daniel Talmor 2020-06-17
CovImmune 2: Study of the Incidence of SARS-CoV-2 Infection Coronavirus disease 19 infection blood sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire De Nice France 2020-07-15 2025-12-31 20-PP-14, CovImmune 2, NCT04429594 Phase Not Applicable Not yet recruiting 1 65 Months 1000 Barbara SEITZ, MCUPH, Barbara SEITZ- POLSKI, Christian PRADIER, barbara SEITZ POLSKI, sonia BOYER SUAVET 2020-06-18
COVID-19 Versus H1N1: Radiological Challenge During Next Influenza Season Rising Coronavirus disease 19 infection, Influenza virus infection, Viral pneumonia GE LightSpeed Plus 4 slice CT scanner (USA) alone, Philips Brilliant-16 (USA) alone, Siemens SOMATOM Sensation 64 (Germany) alone, Siemens SOMATOM Emotion 16 alone, Toshiba Aquilion 64 alone, Toshiba Aquilion CXL/CX 128 (USA) alone, high-resolution computed tomography alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Alexandria Egypt 2020-05-22 2020-06-14 IRB (00012098), SN (0304669), NCT04433039 Phase Not Applicable Completed 1 130 Ahmed Samir, MD 2020-06-18
SURG-SAT-19: COVID-19 - Implications on Surgeons' Burnout and Career Satisfaction Acute stress disorder, Coronavirus disease 19 infection cloud-based software (SurveyMonkey) alone, online survey alone Healthy volunteers accepted Mansoura University Egypt 2020-06-15 2020-08-31 NCT04433286, SURG RES COL 1, SURG-SAT-19 Phase Not Applicable Not yet recruiting 1 2 Months 1000 Ahmed M Elsheikh, MD,MBA,CMQOE, Hosam Hamed, MD, MSc, PhD, Mostafa Shalaby, MD, MSc, PhD 2020-06-29
The Development of Pancreatic Injury in the Course of Severe Acute Respiratory Syndrome Coronavirus-2 Infection Coronavirus disease 19 infection, Pancreas injury, Viral pneumonia biochemical analysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Usak University, Turkey Turkey 2020-03-01 2020-06-12 NCT04433754, USAKU-CEVDET2 Phase Not Applicable Completed 1 3 Months 500 Cevdet Duran 2020-06-18
Clinical study to evaluate the efficiency of specific antibody against SARS-CoV-2 Coronavirus disease 19 infection antibody tests alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yokohama City University Japan Agency for Medical Research and Development Japan 2020-06-22 UMIN000040744 Phase Not Applicable Recruiting 1 5000 Mie Tsuchiya, tomoyuki miyazaki 2020-06-18
Maternal Psychological Implications of Covid-19 Pandemic and Possible Effect on Anesthetic Management Coronavirus disease 19 infection 38-questions questionnaire alone, GAD-7 general anxiety disorder scale alone, PHQ-9 depression scale alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) General and Maternity Hospital of Athens Elena Venizelou Greece 2020-05-15 2020-12-31 MATERNAL COVID 19, NCT04432948 Phase Not Applicable Recruiting 1 7 Months 200 Georgia Micha, Dr 2020-06-18
BNP, Serum Troponin and D-dimer as Risk Factors in Patients With COVID-19 Coronavirus disease 19 infection serum sampling alone Assiut University Egypt 2020-07-01 2021-09-01 CARDIAC MARKERS IN COVID-19, NCT04433026 Phase Not Applicable Not yet recruiting 1 14 Months 90 Areej Osama Ali Mohammed Saleh, Areej Saleh 2020-06-19
A clinical study to assess Tempol for the treatment of subjects with COVID-19 Coronavirus disease 19 infection Tempol (oral, radiotherapy-induced toxicities), Matrix Biomed alone Superoxide dismutase modulator Adamis Pharmaceuticals Corp Phase Not Applicable Planned 0 2020-06-17
Assessment of Mortality Rates in SARS-CoV-2 Infected Populations Treated With Repurposed Medications Coronavirus disease 19 infection Variable regimens including azithromycin , chloroquine , hydroxychloroquine Tabula Rasa HealthCare Inc US 2020-06-15 2021-05-31 COVID-19_TRHCPRESCRIBEWELLNESS, NCT04432350 Phase Not Applicable Not yet recruiting 1 11 Months 50000 Pamela Dow, MS, Veronique Michaud, Veronique Michaud, PhD 2020-06-18
A Phase III trial of COVID-19 vaccine for COVID-19 patients Coronavirus disease 19 infection COVID-19 vaccine (inactivated, Vero cells/intramuscular), Wuhan Institute of Biological Products/Wuhan Institute of Virology, CAS alone Wuhan Institute of Biological Products Co Ltd Phase 3 Clinical Planned 0 2020-06-24
Effect of Opuntia Cactus extract in patients with Covid-19 Coronavirus disease 19 infection, Headache, Myalgia Cactus Opuntia alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Alborz University of Medical Science Iran 2020-07-10 IR.ABZUMS.REC.1399.024, IRCT20200504047298N2 Phase 3 Clinical Not yet recruiting 1 48 Zeinab Siami 2020-06-19
Patients Preferences About Rescheduling Colonoscopies Delayed Due to COVID-19: Cross-Sectional Study Colon tumor, Coronavirus disease 19 infection Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Massachusetts General Hospital US 2020-06-09 2021-04-30 2020P001579-1, NCT04432870 Phase Not Applicable Recruiting 1 10 Months 200 Karen Sepucha, PhD 2020-06-18
COVINOSE: Prospective diagnosis of Covid-19 infection using exhaled breath analysis by electronic nose Coronavirus disease 19 infection eNose alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Leiden University Medical Center Netherlands 2020-04-17 2020-12-31 COVINOSE, NL8694 Phase Not Applicable Recruiting 1 8 Months 200 Geert Groeneveld 2020-06-18
Phase II trial of Rejuveinix for Covid-19 patients Coronavirus disease 19 infection Rejuveinix alone Reven LLC Phase 2 Clinical Planned 0 2020-06-18
Extracorporeal membrane oxygenation in patients with coronavirus disease 2019 Coronavirus disease 19 infection Extracorporeal membrane oxygenation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Amsterdam UMC Netherlands 2020-03-01 2020-12-31 NL8706 Phase Not Applicable Recruiting 1 10 Months 200 Alexander Vlaar 2020-06-18
Quality of life in patients with suspected COVID-19 Coronavirus disease 19 infection Centre of expertise for chronic organ failure Netherlands 2020-06-04 2020-12-01 NL8705 Phase Not Applicable Recruiting 1 5 Months 10000 Martijn Spruit 2020-06-18
A clinical study to assess PolyPEPI-SCoV-2 for the potential treatment of COVID-19 Coronavirus disease 19 infection PolyPEPI-SCoV-2 alone Treos Bio Ltd 2020-10-31 Phase Not Applicable Planned 0 2020-06-23
A clinical trial of mRNA vaccine (COVID-19), University of Tokyo/Daiichi-Sankyo for the potential treatment of COVID-19 infection Coronavirus disease 19 infection mRNA vaccine (COVID-19), University of Tokyo/Daiichi-Sankyo alone Daiichi Sankyo Co Ltd 2021-03-31 Phase Not Applicable Planned 0 2020-06-17
A study to assess the effect of PIKfyve inhibitors for the treatment of COVID-19 infection Coronavirus disease 19 infection PIKfyve inhibitors, Verge Genomics Inc alone Verge Genomics Inc Phase Not Applicable Planned 0 2020-06-17
PPE, COVID-19, HCW Coronavirus disease 19 infection personal protective equipment alone Universiti Malaysia Sarawak Malaysia 2020-05-06 2020-09-30 54908, NMRR-20-878-54908 Phase Not Applicable Not yet recruiting 35 4 Months Haniza Binti Sahdi, Nurul Fatiha binti Zuraidi 2020-06-17
Effects of patients' vision and emotions on covid-19 Coronavirus disease 19 infection, Depression, Vision disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universiti Kebangsaan Malaysia Malaysia 2020-06-15 54953, NMRR-20-1123-54953 Phase Not Applicable Status not specified 2 DR Bannu A/P Jayallan, Dr. Nor Fariza Ngah 2020-06-17
Personality traits, depression, work stress, frontliners, Covid-19 Acute stress disorder, Coronavirus disease 19 infection, Depression Tuanku Jaafar Hospital Malaysia 2020-06-15 2020-12-31 54720, NMRR-20-875-54720 Phase Not Applicable Status not specified 1 6 Months Hj. Binaw Samad 2020-06-17
Incidence of ADR Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Sungai Buloh Malaysia 2020-06-09 55048, NMRR-20-1120-55048 Phase Not Applicable Status not specified 1 2020-06-21
ICRAD: ICRAD Coronavirus disease 19 infection, Rheumatoid arthritis Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sarawak General Hospital Malaysia 2020-07-01 2021-01-01 55262, ICRAD, NMRR-20-1116-55262 Phase Not Applicable Not yet recruiting 1 6 Months 15 Dr Sharifah Aishah bt Wan Mohamad Akba 2020-06-21
Efficacy of a new COVID-19 treatment Coronavirus disease 19 infection artesunate alone, artesunate plus vitamin C Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Malagasy government An Oasis of Healing in Mesa, The LifeCo, University of Mauritius Madagascar 2020-04-29 2020-09-29 PACTR202006899597082 Phase 2 Clinical Not yet recruiting 1 5 Months 60 MIORAMALALA Sedera, RAKOTO Rafanomezantsoa, RAKOTOARIVELO Rivonirina Andry, RAKOTOSAONA Riana, RAKOTOVAO Andriamiadana Luc, RAMANITRAHASIMBOLA David, RAPELANORO RABENJA Fahafahantsoa, RATSIMBASOA Claude Arsene 2020-06-19
Children with disability during the COVID-19 outbreak Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University of Hong Kong Hong Kong 2020-03-23 HKUCTR-2872, UW 20-178, protocol v1-20200306 Phase Not Applicable Not yet recruiting 1 1356 Dr. Wan-yee Winnie Tso, HKUCTR Administrator 2020-06-17
RoKiCo: Prospective study to evaluate immunity to SARS-CoV2 in mothers with children in child-care facilities Coronavirus disease 19 infection biological sampling alone, polymerase chain reaction alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universitätsmedizin Rostock Germany 2020-04-23 A 2020-0090, DRKS00021614, RoKiCo Phase Not Applicable Recruiting 1 400 Dagmar Michel-Lubs, Emil C. Reisinger 2020-06-17
Effects of COVID-19 on lung function and gas exchange Coronavirus disease 19 infection, Interstitial lung disease, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gesellschaft für Tauch- und Überdruckmedizin e.V, University Hospital, Bonn Klinik f. Lungenheilkunde und Beatmungsmedizin, Rhein-Maas Klinikum GmbH Germany 2020-06-16 179/20, DRKS00022082 Phase Not Applicable Not yet recruiting 1 124 Ivanna Rühl, Lars Eichhorn 2020-06-17
PROFLO: Could prone positioning increase lung function for patients with severe COVID-19 infection? Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Viral pneumonia high flow nasal cannula alone, noninvasive ventilation alone, prone positioning alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Uppsala County Council University Hospital of Uppsala Sweden 2020-04-20 2021-06-25 1, ISRCTN54917435, PROFLO Phase Not Applicable Not yet recruiting 2 14 Months 240 Dr Rosen 2020-06-17
Influence of the Covid-19 pandemic on the patient mix in German emergency departments Coronavirus disease 19 infection BundeswehrKrankenhaus Ulm Klinikum WolfsburgZentrale Notfallaufnahme, Otto-von-Guericke-Universität Magdeburg, Universitätsklinik für Unfallchirurgie,AKTIN-Notaufnahmeregister, University Hospital Magdeburg, University Hospital, Aachen Germany 2020-07-01 160/15, DRKS00022188 Phase Not Applicable Not yet recruiting 1 500000 Martin Kulla, Wiebke Schirrmeister 2020-06-17
Exploratory Study Of the Therapeutic Effect and Safety Of Rectal Ozone therapyin Patients Positive To SARS-CoV 2 With Mild To Moderate Symptoms (COVID-19) Coronavirus disease 19 infection conventional therapy alone, rectal ozone therapy alone, Variable regimens including Chloroquine , Heberferon , lopinavir + ritonavir , oseltamivir Exo-alpha sialidase inhibitor, HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Center for Scientific Research, Cuba Cuba 2020-06-08 2020-08-23 OZO-001, RPCEC00000320 Phase Not Applicable Not yet recruiting 1 2 Months Suarez Iznaga, Zamora Rodriguez 2020-06-19
Efficacy and Safety of Sofosbuvir/Daclatasvir treatment in COVID-19: A randomized, controlled study Coronavirus disease 19 infection, Viral pneumonia Standard of care therapy alone, Daktavera plus Gratisovir Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) PHARCO CORPORATE Egypt 2020-06-20 DRKS00022203, IRB0000687, U1111-1253-0458 Phase 2/Phase 3 Clinical Not yet recruiting 1 90 Mostafa Yakoot 2020-06-17
The role of children in transmission of COVID19 pandemic: Two case series in Malaysia Coronavirus disease 19 infection Hospital Sungai Buloh Malaysia 2020-06-01 2020-08-06 NMRR-20-1087-55233 Phase Not Applicable Status not specified 1 2 Months Dr LIM SOK BEE 2020-06-16
Approachs and issues on Corona Disaster for EAP Coronavirus disease 19 infection Psychological education alone Healthy volunteers accepted ADVANTAGE Risk Management Co., Ltd. Japan 2020-06-15 UMIN000040762 Phase Not Applicable Not yet recruiting 1 100 Suzuki Junya 2020-06-16
Covid19HCW: Prevalence of seroconversion of COVID-19 among healthcare worker Coronavirus disease 19 infection RT-PCR test  alone, seroconversion test kits alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HOSPITAL QUEEN ELIZABETH II Malaysia 2020-05-11 2020-07-31 Covid19HCW, NMRR-20-885-54906 Phase Not Applicable Not yet recruiting 1 2 Months Dr Yen Chia How 2020-06-18
Children During the COVID-19 Outbreak Coronavirus disease 19 infection Preschool Children (2-5 yrs), Children (6-12 yrs) The University of Hong Kong Community Child Health Unit Hong Kong 2020-03-23 HKUCTR-2871, UW 20-177, v1-20200305 Phase Not Applicable Not yet recruiting 1 1356 Dr. Winnie Tso, HKUCTR Administrator 2020-06-16
Scientific guidance for risk-control and prevention of COVID-19 in professional soccer-players in Austria Coronavirus disease 19 infection RT-PCR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Paracelsus Medical University Austria 2020-05-18 415-EP/73/820-2020, DRKS00022166 Phase Not Applicable Recruiting 1 250 Dagmar Schaffler 2020-06-17
A real-time national survey OF COVID-19 in hemoglobinopathy and rare inherited anemia patients Anemia, Coronavirus disease 19 infection, Sickle cell anemia, Thalassemia Queen Mary University of London UK Phase Not Applicable Status not specified 1 2020-06-16
GI IN COVID-19 Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Queen Elizabeth Malaysia 2020-05-18 2020-12-31 54764, NMRR-20-869-54764 Phase Not Applicable Recruiting 1 7 Months 200 Dr Ho Yoke Fun 2020-06-17
Psychosocial experiences among quarantined healthcare workers Coronavirus disease 19 infection Universiti Malaysia Sarawak Malaysia 2020-07-01 2020-09-30 54833, NMRR-20-1144-54833 Phase Not Applicable Not yet recruiting 2 3 Months Prof. Chew Keng Sheng 2020-06-17
Studying tobacco use and quitting behavior due to the coronavirus lockdown in India Coronavirus disease 19 infection interviewer-administered telephone-based survey alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HRIDAY, Public Health Foundation of India University of Edinburgh India 2020-06-20 CTRI/2020/06/025850, HMSC proposal ref id: 2020-9500 Phase Not Applicable Not yet recruiting 1 800 Dr Monika Arora, Prof K Srinath Reddy 2020-06-18
RNB in UPUMS, Saifai Coronavirus disease 19 infection RNB (Raj Nirvan Bati) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Uttar Pradesh University of Medical Sciences India 2020-06-14 CTRI/2020/06/025852 Phase 1/Phase 2 Clinical Not yet recruiting 1 Dr Raj Kumar 2020-06-17
Mental Health of children during COVID-19 Pandemic Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs) ESI Post Graduate Institute of Medical Science and Research (PGIMSR) India 2020-06-17 CTRI/2020/06/025853 Phase Not Applicable Not yet recruiting 1 100 Jyoti Bagla, Mahima Rajan 2020-06-17
BCG for COVID-19: BCG Vaccination against COVID-19 Coronavirus disease 19 infection, Respiratory disease BCG vaccine alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Indian Council of Medical Research India 2020-06-25 BCG for COVID-19, CTRI/2020/06/025854, Version 3.2 Phase 4 Clinical Not yet recruiting 6 1450 C Padmapriyadarsini, Dr Anant Mohan, Dr Asha Keetharam, Dr C Padmapriyadarsini, Dr R R Tiwari, Dr Rujuta Hadaye, Dr Toteja, Srikanth Tripathy 2020-06-17
DEFEAT-COVID: A clinical trial of leflunomide for the treatment of COVID-19 infection Coronavirus disease 19 infection leflunomide alone Dihydroorotate dehydrogenase inhibitor, Protein tyrosine kinase inhibitor Ashford and St. Peter's Hospitals NHS Trust LifeArc UK, China DEFEAT-COVID Phase Not Applicable Status not specified 2 2020-06-20
FLARE: A randomised, double-blind, 2×2 factorial placebo-controlled trial on the saftey and efficacy Favipiravir, lopinavir/ritonavir combination therapy in early antiviral therapy in COVID-19 infection Coronavirus disease 19 infection favipiravir plus lopinavir + ritonavir HIV protease inhibitor, RNA polymerase inhibitor University of London LifeArc UK FLARE Phase Not Applicable Status not specified 1 2020-06-16
Short-term Outcome of COVID-19 Surgical Patients: Case-series of a High-risk Area Community Hospital Coronavirus disease 19 infection surgical procedure alone Azienda Socio Sanitaria Territoriale di Lodi Italy 2020-05-01 2020-05-30 COVID19NR1, NCT04430062 Phase Not Applicable Completed 1 14 Michele Ballabio 2020-06-18
Clinical Analysis of Patients Hospitalized Due To COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) TNMC and BYL Nair Hospital India 2020-06-21 CTRI/2020/06/025848 Phase Not Applicable Not yet recruiting 1 1500 Minal Harde, Rakesh Bhadade 2020-06-17
Study to Evaluate the Safety and Efficacy of a Combination of Nitazoxanide and Hydroxychloroquine Versus Hydroxychloroquine Alone in COVID-19 Patients Coronavirus disease 19 infection hydroxychloroquine plus nitazoxanide Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Dr Reddy's Laboratories Ltd India 2020-06-15 CTRI/2020/06/025849, CVD-19-CD-001 Phase 2 Clinical Not yet recruiting 1 158 D Mallikarjuna Rao, Dr Apurva Agarwal 2020-06-17
Safety, Tolerability and Efficacy of Nangibotide in Mechanically Ventilated Patients With COVID-19 and Features of Systemic Inflammation Coronavirus disease 19 infection, Inflammatory disease, Respiratory failure nangibotide alone, standard of care alone TREM receptor 1 antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Inotrem SA France 2020-06-30 2021-03-31 MOT-C-204, NCT04429334 Phase 2 Clinical Not yet recruiting 1 9 Months 60 Jean-Jacques Garaud, MD, Sébastien Gibot, MD 2020-06-22
Pre-Identified Homoeopathic Medicines In Asymptomatic Covid -19 Individuals Receiving Standard Treatment Protocol Coronavirus disease 19 infection Standard treatment alone, Variable regimens including Arsenicum album 30 , Bryonia 30 , Camphora 1M Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Homoeopathy India 2020-06-22 CTRI/2020/06/025844 Phase 2/Phase 3 Clinical Not yet recruiting 1 Dr Anil Khurana, Dr Varanasi Roja 2020-06-19
Registry for a Cardiovascular Patient Who COVID-19 Infection in Qatar and Gulf Acute coronary syndrome, Cardiac arrest, Coronavirus disease 19 infection, Heart arrhythmia, Myocarditis transthoracic echocardiography alone, ultrasound alone Hamad Medical Corp Qatar 2020-06-02 2020-12-31 MRC-05-113, NCT04430374 Phase Not Applicable Recruiting 1 6 Months 100 DR.Jassim Alsuwaidi Senior Consultant, Dr.Jassim Alsuwaidi Senior Consultant, MRC 2020-06-29
COVIpreg-UK: Studying the immune response and long-term morbidity of COVID-19 infection in pregnancy Coronavirus disease 19 infection Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Queen Mary University of London February Foundation UK 2020-05-07 2022-06-06 COVIpreg-UK, IRAS 283699, ISRCTN93266696 Phase Not Applicable Recruiting 1 25 Months 200 Dr Dodds, Dr Stamatina Iliodromiti 2020-06-16
A phase III trial of Inactivated vaccine (COVID-19), Sinovac Biotech for COVID-19 Coronavirus disease 19 infection CoronaVac alone Instituto Butantan, Sinovac Biotech Ltd Brazil Phase 3 Clinical Planned 1 2020-06-18
COVID-AIIMS: Low Dose Radiation Therapy for COVID-19 Coronavirus disease 19 infection, Viral pneumonia low dose radiation therapy (70 cGy) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-06-13 COVID-AIIMS, CTRI/2020/06/025862, LDRT-Covid-19 Phase 1 Clinical Recruiting 1 10 Daya Nand Sharma 2020-06-22
Scientific evaluation of Immuno-modulatory effects of Ayush interventions on normal healthy and high-risk individuals in context with COVID-19 pandemic: An open-level study Coronavirus disease 19 infection Anu Taila put alone, Variable regimens including Amritadi Guggul , Ashwagandha Churna , Ashwagandha Vati , Ayush Raksha Kwath , Madhyashti Churna , Pippali Churna , Pippalimool Churna , Sanshmani Vaati , Shunthi Churna , kwath churna Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Department of Ayush Uttarakhand India 2020-06-20 CTRI/2020/06/025861 Phase 3 Clinical Not yet recruiting 9 500 Dr Alok Kumar Shukla, Dr Ashok Kumar Tiwari, Dr Avnish Kumar Upadhyay, Dr Deshraj Singh, Dr Jaideep Singh Bisht, Dr Krishna Kant Pandey, Dr Pankaj Kumar, Dr Rakesh Kumar Agarwal, Dr Sandeep Kumar, Dr Saroj Kumar Mishra, Dr Sunil Kumar Raturi, Dr Swastik Suresh 2020-06-22
EPIC 19: Observational study on suspected COVID 19 patients admitted to ICU Coronavirus disease 19 infection, Respiratory disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Johns Medical College India 2020-06-22 CTRI/2020/06/025858, EPIC 19 Phase Not Applicable Not yet recruiting 1 500 Dr Amarja Ashok Havaldar 2020-06-22
CELMA: Safety and Efficacy of Mesenchymal Stem Cells in the Management of Severe COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia Usual treatment alone, allogeneic human umbilical cord-derived mesenchymal stem cells (COVID-19), Trustem alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Trustem Fundación Universitaria de Ciencias de la Salud, Hospital Infantil Universitario de San Jose, Hospital de San Jose 2020-07-31 2020-11-30 202001, CELMA, NCT04429763 Phase 2 Clinical Not yet recruiting 0 4 Months 30 Carlos Escobar-Soto, MD, PhD, Carolina Araque, MD, Esp, Guillermo Sánchez-Vanegas, MD, PhD, Jhon Jaime Sprockel Díaz, MD, Esp 2020-06-26
Safety of TY-027, a Treatment for COVID-19, in Humans Coronavirus disease 19 infection TY-027, Tychan alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Tychan Pte Ltd Singapore 2020-06-09 2021-01-31 NCT04429529, SCT-001 Phase 1 Clinical Recruiting 1 7 Months 25 Anjali Baglody, MSc, Bo Hong Tay, Jenny Low, MBBS, Justin Ng, PhD, Shayne Lin 2020-06-17
LCECS: Development and Application of a Low-Cost Ear-Contactless Stethoscope Powered by Raspberry Pi and Python Coronavirus disease 19 infection Low-Cost Ear-Contactless Stethoscope alone Healthy volunteers accepted Shengjing Hospital of China Medical University China 2020-06-12 2021-06-12 ChiCTR2000033830, LCECS Phase Not Applicable Not yet recruiting 1 12 Months 12 Chuan Yang 2020-06-17
A phase III clinical study of SARS-CoV-2 vaccine, Ad26.COV2-S for the treatment of COVID-19 Coronavirus disease 19 infection SARS-CoV-2 recombinant adenoviral vector vaccine (AdVac/PER.C6, COVID-19), Johnson & Johnson/Biomedical Advanced Research and Development Authority/Beth Israel Deaconess Medical Center alone Johnson & Johnson Phase 3 Clinical Planned 0 2020-06-15
COMETE-19: Covid-19 at the Regional Medical Center Metz-Thionville: a Descriptive Study Coronavirus disease 19 infection Centre Hospitalier Régional Metz-Thionville France 2020-03-01 2021-06-30 2020-02OBS-CHRMT, COMETE-19, NCT04430322 Phase Not Applicable Recruiting 1 16 Months 330 Nadia OUAMARA, Rostane GACI, MD, Vincent DINOT 2020-06-19
Hydroxychloroquine Use in Hospitalized Patients With COVID-19: Impact on Progression to Severe or Critical Disease Coronavirus disease 19 infection hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) WellStar Health System US 2020-05-07 2020-12-07 1604885, NCT04429867 Phase 4 Clinical No longer recruiting 1 7 Months 700 2020-06-18
OpMiCoV: Explorative Study of the Association of Oropharyngeal Microbiota Profiles with SARS-CoV-2 Infection and COVID-19 disease Coronavirus disease 19 infection, Upper respiratory tract infection, Viral pneumonia Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Deutsches Krebsforschungszentrum Germany 2020-04-02 DRKS00021424, OpMiCoV, S-194/2020, U1111-1253-4873 Phase Not Applicable No longer recruiting 1 360 Christoph Stein-Thoeringer 2020-06-17
Epidemiological and Demographic Data From 150 Patients Diagnosed With Coronavirus Disease 2019 Pneumonia Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sisli Etfal Hospital Turkey 2020-05-15 2020-06-05 DM3334, NCT04430023 Phase Not Applicable Completed 1 150 AYŞE SÜRHAN ÇINAR, ayse cinar 2020-06-18
Health Professional Exposure Assessment to Covid-19 (SERODRON) Coronavirus disease 19 infection RT-PCR test alone, blood sampling alone, serological test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier de Tourcoing France 2020-06-30 2020-12-31 NCT04429724, RIPH_2020_8 Phase Not Applicable Not yet recruiting 3 6 Months 6000 Pierre PATOZ, PharmD, SIVERY, Solange TREHOUX, PhD, VACHEE 2020-06-17
MAGIC: Impact of Smoking and Nicotine on the Risk of Being Infected With COVID-19 Coronavirus disease 19 infection, Nicotine dependence nicotine substitute therapy alone, serological test alone, smoking cessation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Nancy, France France 2020-07-01 2021-04-01 2020-A01681-38, MAGIC, NCT04429815 Phase Not Applicable Not yet recruiting 1 9 Months 489 Christian Rabaud 2020-06-16
A study to predict the disease progression in COVID-19 patients by analyzing blood samples of these patients from using high-throughput mass spectrometry platform Coronavirus disease 19 infection high-throughput mass spectrometry alone Charite Universitaetsmedizin Berlin The Francis Crick Institute UK Phase Not Applicable Status not specified 1 31 Prof. Dr. Markus Ralser 2020-06-15